Nausheen Akhter

ORCID: 0000-0001-9423-8578
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About
Contact & Profiles
Research Areas
  • Chemotherapy-induced cardiotoxicity and mitigation
  • Cardiac Imaging and Diagnostics
  • Cardiac Structural Anomalies and Repair
  • Chronic Lymphocytic Leukemia Research
  • Cardiovascular Function and Risk Factors
  • Cancer Treatment and Pharmacology
  • Heart Failure Treatment and Management
  • Cardiac tumors and thrombi
  • CAR-T cell therapy research
  • Takotsubo Cardiomyopathy and Associated Phenomena
  • Lymphoma Diagnosis and Treatment
  • Cancer Immunotherapy and Biomarkers
  • Pericarditis and Cardiac Tamponade
  • Cardiac Valve Diseases and Treatments
  • COVID-19 and healthcare impacts
  • HER2/EGFR in Cancer Research
  • Melanoma and MAPK Pathways
  • Healthcare cost, quality, practices
  • Cancer-related cognitive impairment studies
  • Advancements in Semiconductor Devices and Circuit Design
  • Acute Myocardial Infarction Research
  • Viral Infections and Immunology Research
  • Cardiovascular Effects of Exercise
  • Cardiovascular Health and Risk Factors
  • Vitamin D Research Studies

Northwestern University
2015-2025

Northwestern Medicine
2017-2024

Cleveland Clinic Florida
2024

Cleveland Clinic
2024

Northwestern Memorial Hospital
2016-2023

University Medical Center
2023

Dana-Farber Cancer Institute
2021

Cardiovascular Institute of the South
2018-2020

Memorial Hospital of Rhode Island
2012

University of Chicago Medical Center
2008-2009

Immune checkpoint inhibitors (ICIs) are approved for multiple cancers but can result in ICI-associated myocarditis, an infrequent life-threatening condition. Elevations cardiac biomarkers, specifically troponin-I (cTnI), troponin-T (cTnT), and creatine kinase (CK), used diagnosis. However, the association between temporal elevations of these biomarkers with disease trajectory outcomes has not been established.

10.1161/circulationaha.123.062405 article EN Circulation 2023-06-15
Charlotte Fenioux Baptiste Abbar Samia Boussouar Marie Bretagne John R. Power and 95 more Javid J. Moslehi Paul Gougis Damien Amelin Agnès Dechartres Lorenz Lehmann Pierre‐Yves Courand Jennifer Cautela Joachim Alexandre Adrien Procureur Antoine Rozes Sarah Léonard-Louis Juan Qin Nausheen Akhter Nazanin Aghel Kingsley Amidi Élizabeth Anderson Dimitri Arangalage Mandar A. Aras Aarti Asnani Lauren A. Baldassarre Rocio Barovila Ana Sofia Barroso Wendy Bottinor Anissa Bouali Eve Cariou Wei‐Ting Chang Richard K. Cheng Shanthini M. Crusz Anita Deswal Pierre‐Yves Dietrich Grace K. Dy Clémence Docq Steven M. Ewer Suran L. Fernando Danette L. Flint Roberta Florido Satoshi Fukushima Elena Galli Elizabeth Gaughan Manhal Habib Andrew Haydon Lucie Heinzerling Osnat Itzhaki Ben Zadok N. Issa Anja Karlstaedt Kazuo Kitagawa Michael Layoun Michal Laufer‐Perl Carrie Lenneman Darryl P. Leong Chloé Lesiuk Joshua Levenson Teresa López‐Fernández Yan Liu Kristen Machado Pedro Moliner Ryota Morimoto Michel Obéid Anna Narezkina Nicolas L. Palaskas Giovanni Peretto Nicolas Piriou Juan Carlos Plana Peter P. Rainer Maxime Robert‐Halabi Fanny Rocher Eugenia Rota François Roubille Theresa Ruf Shahneen Sandhu Francis Sanjeev Nobuhiko Seki Kazuko Tajiri Yuichi Tamura Franck Thuny Romain Trésorier Isik Turker Ellen Warner Vlad G. Zaha Han Zhu Rémi Cheynier Bénédicte Charmeteau-De Muylder Alban Redheuil Florence Tubach Jacquès Cadranel Audrey Milon Stéphane Éderhy Thomas Similowski Douglas B. Johnson Ian Pizzo Toniemarie Catalan Olivier Benveniste Salim S. Hayek Yves Allenbach Michèlle Rosenzwajg

10.1038/s41591-023-02591-2 article EN Nature Medicine 2023-10-26

Cardiovascular disease is a leading cause of death in cancer survivors. It critical to apply new predictive and early diagnostic methods this population, as can potentially inform cardiovascular treatment surveillance decision-making. We discuss the application artificial intelligence (AI) technologies imaging cardio-oncology, with particular emphasis on prevention targeted variety conditions patients. Recently, use AI-augmented cardiac cardio-oncology gaining traction. A large proportion...

10.1016/j.ahjo.2022.100126 article EN cc-by-nc-nd American Heart Journal Plus Cardiology Research and Practice 2022-03-01

10.1016/j.ejca.2022.07.018 article EN publisher-specific-oa European Journal of Cancer 2022-08-24

Cardiovascular adverse events (CVAEs) are recognized complications of chimeric antigen receptor (CAR) T-cell therapies. However, data lacking regarding subtypes that develop in patients with different malignancies, and little is known about the timeframe which cardiotoxicities most likely to occur post-CAR In this study, 211 patients, including 138 lymphoma 66 myeloma who received CAR therapies were retrospectively identified. Of these, 42 (19.9%) developed CVAEs post-treatment. Myeloma...

10.1080/10428194.2024.2448713 article EN Leukemia & lymphoma/Leukemia and lymphoma 2025-01-07

Data on the safety profiles and clinical outcomes of patients with solid tumors cardiac metastasis treated immune checkpoint inhibitors (ICIs) are limited. This is an international multicenter retrospective study cancer at baseline. Patients who had received ≥1 dose ICI were included. Treatment-related adverse events (trAEs) graded per Common Terminology Criteria for Adverse Event V.5.0. Objective response rates (ORR) evaluated by Response Evaluation in Solid Tumors V.1.1 when available....

10.1136/jitc-2024-009364 article EN cc-by-nc-nd Journal for ImmunoTherapy of Cancer 2025-03-01

Background: Preterm Premature Rupture of Membranes (PPROM) is a significant obstetric complication associated with adverse maternal and neonatal outcomes. Identifying early hematological markers could aid in risk prediction preventive strategies. This study investigates the association between Mean Platelet Volume (MPV) Count (PC) measured at 11–13 weeks gestation PPROM. Methods: prospective cohort was conducted Department Fetomaternal Medicine Obstetrics Gynecology, Bangabandhu Sheikh Mujib...

10.36348/sijog.2025.v08i03.005 article EN Scholars International Journal of Obstetrics and Gynecology 2025-03-12

10.1016/s0735-1097(25)04984-8 article EN Journal of the American College of Cardiology 2025-03-30

Purpose This study was performed to determine if there is a sex-based bias in referral practices, complexity of disease, surgical treatment, or outcomes patients undergoing mitral valve surgery at our institution. Methods Data were collected from the Cardiovascular Research Database Clinical Trial Unit Bluhm Institute Northwestern Memorial Hospital and they defined according Society Thoracic Surgeons National ( www.sts.org ). All who had replacement, repair with annuloplasty ring placement,...

10.1177/2047487319833307 article EN European Journal of Preventive Cardiology 2019-03-04
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