T. Bednarski
A5081879463- Medical Imaging Techniques and Applications
- Radiation Detection and Scintillator Technologies
- Atomic and Subatomic Physics Research
- Particle physics theoretical and experimental studies
- Adipose Tissue and Metabolism
- Quantum Chromodynamics and Particle Interactions
- Particle Detector Development and Performance
- Nuclear Physics and Applications
- Muon and positron interactions and applications
- Diet and metabolism studies
- High-Energy Particle Collisions Research
- Nuclear physics research studies
- Peroxisome Proliferator-Activated Receptors
- Liver Disease Diagnosis and Treatment
- Lipid metabolism and biosynthesis
- Advanced MRI Techniques and Applications
- Metabolism and Genetic Disorders
- Radiomics and Machine Learning in Medical Imaging
- Diet, Metabolism, and Disease
- Metabolism, Diabetes, and Cancer
- Mitochondrial Function and Pathology
- Advanced Radiotherapy Techniques
- Metabolomics and Mass Spectrometry Studies
- Radiation Therapy and Dosimetry
- Cardiovascular Function and Risk Factors
Vanderbilt University
2020-2024
University of Nebraska–Lincoln
2023
Instytut Biologii Doświadczalnej im. Marcelego Nenckiego
2013-2022
Polish Academy of Sciences
2016-2022
Nashville Oncology Associates
2019-2021
Jagiellonian University
2011-2020
Ludwig-Maximilians-Universität München
2016
TU Dresden
2016
Maria Curie-Skłodowska University
2015
Délégation Paris 6
2014
We report on an exclusive and kinematically complete high-statistics measurement of the basic double-pionic fusion reaction pn→dπ(0)π(0) over full energy region ABC effect, a pronounced low-mass enhancement in ππ-invariant mass spectrum. The measurements, which cover also transition to conventional t-channel ΔΔ process, were performed with upgraded WASA detector setup at COSY. data reveal Abashian-Booth-Crowe effect be uniquely correlated Lorentzian dependence integral cross section....
In this article it is presented an FPGA based $M$ulti-$V$oltage $T$hreshold (MVT) system which allows of sampling fast signals ($1-2$ ns rising and falling edge) in both voltage time domain. It possible to achieve a precision measurement $20$ ps RMS reconstruct charge signals, using simple approach, with deviation from real value smaller than 10$\%$. Utilization the differential inputs chip as comparators together implementation TDC inside allowed us compact multi-channel characterized by...
Recent tests of a single module the Jagiellonian Positron Emission Tomography system (J-PET) consisting 30 cm long plastic scintillator strips have proven its applicability for detection annihilation quanta (0.511 MeV) with coincidence resolving time (CRT) 0.266 ns. The achieved resolution is almost by factor two better respect to current TOF-PET detectors and it can still be improved since, as shown in this article, intrinsic limit determination interaction 0.511 MeV gamma scintillators...
We present a study of the application Jagiellonian positron emission tomograph (J-PET) for registration gamma quanta from decays ortho-positronium (o-Ps). The J-PET is first tomography scanner based on organic scintillators in contrast to all current PET scanners inorganic crystals. Monte Carlo simulations show that as an axially symmetric and high acceptance can be used multi-purpose detector well suited pursue research including e.g. tests discrete symmetries addition medical imaging....
An exclusive measurement of the excitation function for dd->3Heppi- reaction was performed at Cooler Synchrotron COSY-Juelich with WASA-at-COSY detection system. The data were taken during a slow acceleration beam from 2.185 GeV/c to 2.400 crossing kinematic threshold eta meson production in dd->4He-eta 2.336 GeV/c. corresponding excess energy respect 4He-eta system varied -51.4MeV 22MeV. integrated luminosity experiment determined using dd->3Hen reaction. shape examined. No signal bound...
Cardiac hypertrophy is accompanied by molecular remodeling that affects different cellular pathways, including fatty acid (FA) utilization. In the present study, we show cardiac lipid metabolism differentially regulated in response to physiological (endurance training) and pathological [abdominal aortic banding (AAB)] hypertrophic stimuli. Physiological was an increased expression of lipogenic genes activation sterol regulatory element-binding protein-1c Akt signaling. Additionally, FA...
The Jagiellonian Positron Emission Tomograph (J-PET) was constructed as a prototype of the cost-effective scanner for simultaneous metabolic imaging whole human body. Being optimized detection photons from electron-positron annihilation with high time- and angular-resolution, it constitutes multi-purpose detector providing new opportunities studying decays positronium atoms. Positronium is lightest purely leptonic object decaying into photons. As an atom bound by central potential parity...
In this paper, we present a complete Data Acquisition System (DAQ) together with the readout mechanisms for J-PET tomography scanner.In general, detector chain is constructed out of Front-End Electronics (FEE) measurement devices such as Time-to-Digital or Analog-to-Digital Converters (TDCs ADCs), data collectors and storage.We have developed system capable maintaining continuous digitized without preliminary selection.Such operation mode results in up to 8 Gbps stream, therefore, it...
In this paper we estimate the time resolution of J-PET scanner built from plastic scintillators. We incorporate method signal processing using Tikhonov regularization framework and kernel density estimation method. obtain simple, closed-form analytical formulae for resolution. The proposed is validated signals registered by means single detection unit tomograph a 30 cm long scintillator strip. It shown that experimental theoretical results obtained equipped with vacuum tube photomultipliers...
There is much speculation and a modest amount of evidence that certain mesons might form quasi-bound states with nuclei to produce really exotic matter.For this be practical possibility, the interaction between meson nucleons at low energies must strong attractive production rates "healthy".The conditions for are surveyed K, η, ω, η , φ mesons.How lead then discussed in few typical cases.Though some interesting effects have been seen above-threshold data, search experimental signals these...
The liver is the major source of glucose production during fasting under normal physiological conditions. However, kidney may also contribute to maintaining homeostasis in certain circumstances. To test ability compensate for impaired hepatic vivo, we developed a stable isotope approach simultaneously quantify gluconeogenic and oxidative metabolic fluxes kidney. Hepatic gluconeogenesis from phosphoenolpyruvate was disrupted via liver-specific knockout cytosolic carboxykinase (PEPCK-C; KO)....
Abstract This article presents an application of a novel technique for precise measurements time and charge based solely on field programmable gate array (FPGA) device positron emission tomography (PET). The described approach simplifies electronic circuits, reduces the power consumption, lowers costs, merges front-end electronics with digital electronics, also makes more compact final design. Furthermore, it allows to measure when analog signals cross reference voltage at different...
J-PET analysis framework is a exible, lightweight, ROOT-based software package which provides the tools to develop reconstruction and calibration procedures for PET tomography.In this article we present implementation of full data-processing chain in used data tomography scanner.The incorporates automated handling setup parameters' database as well high level building procedures.Each these components briey discussed.
Exclusive and kinematically complete high-statistics measurements of the double pionic fusion reaction $dd \to ^4$He$\pi^0\pi^0$ have been performed in energy range 0.8 - 1.4 GeV covering thus region ABC effect, which denotes a pronounced low-mass enhancement $\pi\pi$-invariant mass spectrum. The experiments were carried out with WASA detector setup at COSY. Similar to observation basic $pn d \pi^0\pi^0$ reaction, data reveal correlation between effect resonance-like dependence total cross...
Abstract This article is focused on data acquisition system (DAQ) designed especially to be used in positron emission tomography (PET) or single-photon computed tomography. The allows for continuous registration of analog signals during measurement. It has been optimize and processing the information carried by from detector PET scanner. does not require any rejection with a trigger system. proposed possesses also an ability implement various analysis algorithms that can performed real time...