A5022581615- Coronary Interventions and Diagnostics
- Cardiac Imaging and Diagnostics
- Cerebrovascular and Carotid Artery Diseases
- Peripheral Artery Disease Management
- Cardiovascular Disease and Adiposity
- Cardiac Valve Diseases and Treatments
- Acute Myocardial Infarction Research
- Antiplatelet Therapy and Cardiovascular Diseases
- Cardiovascular Function and Risk Factors
- Lipoproteins and Cardiovascular Health
- Aortic aneurysm repair treatments
- Cardiac pacing and defibrillation studies
- Hemodynamic Monitoring and Therapy
- Vascular Procedures and Complications
- Cardiac and Coronary Surgery Techniques
- Cardiac, Anesthesia and Surgical Outcomes
- Renal and Vascular Pathologies
- Cardiac Arrhythmias and Treatments
- Aortic Disease and Treatment Approaches
- Atrial Fibrillation Management and Outcomes
- Aortic Thrombus and Embolism
- Cardiac electrophysiology and arrhythmias
- Infective Endocarditis Diagnosis and Management
- Cardiac Ischemia and Reperfusion
- Inflammatory mediators and NSAID effects
Aichi Medical University
2014-2024
Stanford University
2009-2021
Japanese Circulation Society
2019
Stanford Medicine
2007-2018
Cardiovascular Institute of the South
2015
Seoul National University Hospital
2010-2014
Prince Charles Hospital
2011
Royal Adelaide Hospital
2011
Auckland City Hospital
2011
St Vincent's Hospital
2011
Background— We sought to investigate the mechanism of geometric changes after main branch (MB) stent implantation and identify predictors functionally significant “jailed” side (SB) lesions. Methods Results— Seventy-seven patients with bifurcation lesions were prospectively enrolled from 8 centers. MB intravascular ultrasound was performed before implantation, fractional flow reserve measured in jailed SB. The vessel volume index both proximal distal increased implantation. plaque decreased...
Background: The prognostic impact of coronary microvascular dysfunction after percutaneous intervention (PCI) remains unclear in patients with stable artery disease. This study sought to investigate the value function measured immediately PCI Methods: We enrolled 572 disease who underwent and elective measurement index microcirculatory resistance (IMR) from 8 centers 4 countries. Impaired was defined as IMR≥25 (high IMR). Major adverse cardiac events, including death, myocardial infarction...
Microvascular resistance reserve (MRR) has been proposed as a specific metric to quantify coronary microvascular function. The long-term prognostic value of MRR measured in stable patients immediately after percutaneous intervention (PCI) is unknown. This study sought determine the PCI with artery disease.
Objectives We performed this study to evaluate the variability of fractional flow reserve (FFR) values which were measured from various methods hyperemia induction. Background Concerns have been raised regarding FFR due different routes for hyperemic agent administration and agents targeting receptors induce maximal hyperemia. Methods A total 656 intermediate coronary lesions 628 patients with artery disease analyzed. Among them, 238 underwent measurement induced by both intravenous (IV)...
To report the clinical outcome of stent-assisted below-the-ankle angioplasty for limb salvage in setting critical ischemia (CLI).A retrospective single-center study was conducted 40 ischemic limbs 31 patients (mean age 67 ± 8 years, range 46-94) undergoing between April 2006 and 2009. Coronary bare metal stents were implanted cases failed balloon due to significant recoil, flow-limiting dissection, abrupt closure, or repeat early reocclusion.Technical success 93% (37 limbs), with 3 failures...
Objectives Cigarette smoking is associated with atherosclerosis and an important risk factor for cardiovascular disease. We evaluated the impact of cigarette on coronary plaque composition using integrated backscatter intravascular ultrasound (IB-IVUS). Methods A total 143 consecutive patients undergoing percutaneous intervention were enrolled. history illness, as well habits, was obtained by interview. Participants asked to report whether they current smokers, had quit smoking, or never...
Tolvaptan (TLV) has an inhibiting effect for worsening renal function (WRF) in acute decompensated heart failure (HF) patients. However, there are limited data regarding the of continuous TLV administration on medium-term WRF.
Background Recent lipid-lowering trials have reported that statin therapy may retard progression or stimulate regression of human coronary plaque. In the present study volumetric intravascular ultrasound (IVUS) analyses were performed to investigate effect pitavastatin, a newly developed statin, on Methods and Results Eighty-two patients matched for age gender from 870 consecutive undergoing IVUS guided percutaneous intervention retrospectively assigned either (n=41; pitavastatin 2 mg/day)...
Our aim was to evaluate the safety and efficacy of intracoronary (IC) nicorandil as an alternative choice hyperaemic agent for invasive physiologic studies.A total 480 intermediate coronary lesions from 429 patients enrolled six Japanese Korean centres were analysed. IC showed earlier achievement hyperaemia (time lowest FFR: 18.0 s [1st 3rd quartile value 15.6-21.5] vs. 44.0 [36.0-60.0], p<0.001) with similar efficacy, compared intravenous (IV) adenosine/ATP (FFR 0.82 [0.75-0.87]...
Abstract Objective : We sought to evaluate the variability in assessment of jailed side branch (SB) lesions by visual estimation and quantitative coronary angiography (QCA) compare those results with fractional flow reserve (FFR). Methods Twenty SB available FFR (median 0.76; range, 0.39–0.94) were selected from PRESSURE trial. Lesions assessed three independent QCA core laboratories different systems cardiologist groups (five European bifurcation club members, five Korean experts,...
Polymer formulation may affect the efficacy of drug-eluting stents. Resolute, Endeavor, and ZoMaxx are zotarolimus-eluting stents with different stent platforms polymer coatings have been tested in clinical trials. The aim this analysis was to compare polymers.Data were obtained from first-in man trial or first randomized trials each stent, Clinical RESpOnse EvaLUation MedTronic Endeavor CR ABT-578 Eluting Coronary Stent System De Novo Native Artery Lesions (RESOLUTE), Randomized Controlled...
Background Although angiotensin II receptor blockers (ARB) have been found to reduce the coronary atherosclerotic plaque burden in animal models, it is unknown whether ARB a similar effect on human arteries. Methods and Results Serial intravascular ultrasound (IVUS) studies of left main (LM) artery were performed 64 patients at baseline after 7-month follow-up. All divided into 2 groups (ARB group: 23 patients; non-ARB 41 patients). Three-dimensional volumetric analysis was done throughout...