- Viral Infections and Vectors
- Intracranial Aneurysms: Treatment and Complications
- SARS-CoV-2 and COVID-19 Research
- Vascular Malformations Diagnosis and Treatment
- COVID-19 Clinical Research Studies
- Fire effects on ecosystems
- Mosquito-borne diseases and control
- Long-Term Effects of COVID-19
- Cerebrovascular and Carotid Artery Diseases
- Viral Infections and Outbreaks Research
- Intracerebral and Subarachnoid Hemorrhage Research
- Cerebral Venous Sinus Thrombosis
- Dental Research and COVID-19
- vaccines and immunoinformatics approaches
- Neurosurgical Procedures and Complications
- Healthcare and Venom Research
- Acupuncture Treatment Research Studies
- Polyoxometalates: Synthesis and Applications
- Bacteriophages and microbial interactions
- Photonic and Optical Devices
- Gut microbiota and health
- Venous Thromboembolism Diagnosis and Management
- Traumatic Brain Injury and Neurovascular Disturbances
- Herpesvirus Infections and Treatments
- Chromatography in Natural Products
Yangzhou University
2025
Wenzhou Medical University
2019-2024
Zhoushan Hospital
2018-2024
Sun Yat-sen University
2019-2023
Third Affiliated Hospital of Sun Yat-sen University
2019-2023
Yunnan University
2022-2023
Zhujiang Hospital
2008-2021
Tianjin Medical University Cancer Institute and Hospital
2020
Huazhong University of Science and Technology
2015-2019
Central Hospital of Wuhan
2019
Several potent neutralizing antibodies against severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) virus have been identified. However, antibody-dependent enhancement (ADE) has not comprehensively studied for SARS-CoV-2, and the relationship between enhancing versus activities antibody epitopes remains unknown. Here, we select a convalescent individual with IgG activity characterize his response. Monoclonal isolated from memory B cells target four groups of five non-overlapping...
Abstract: Combination of chlorhexidine (CHX) and silver ions could engender synergistic bactericidal effect improve the efficacy. It is highly desired to develop an efficient carrier for antiseptics codelivery targeting infection foci with acidic microenvironment. In this work, monodisperse mesoporous silica nanoparticle (MSN) nanospheres were successfully developed as ideal CHX nanosilver through a facile environmentally friendly method. The CHX-loaded, silver-decorated nanoparticles (...
Background and Purpose— The relationship between infarct dimensions neurological progression in patients with acute pontine infarctions remains unclear. This study aimed to investigate the morphometric predictive value of magnetic resonance imaging for early deterioration (END) infarction. Methods— We included all admitted our department having an ischemic stroke pons. ventrodorsal length multiplied by thickness was measured as parameters size. END defined incremental increase National...
COVID-19 has emerged as a global pandemic, challenging the world's economic and health systems. Human oral microbiota comprises second largest microbial community after gut is closely related to respiratory tract infections; however, microbiomes of patients who have recovered from not yet been thoroughly studied. Herein, we compared bacterial fungal clearance SARS-CoV-2 in 23 those 29 healthy individuals. Our results showed that both diversity were nearly normalized patients. The relative...
Severe fever with thrombocytopenia syndrome (SFTS) is an emerging infectious disease caused by SFTS bunyavirus (SFTSV), a tick borne bunyavirus. However, Immunohistochemistry of patients are not well studied. We obtained multiple tissues from fatal case SFTS, including blood, lungs, kidneys, heart, and spleen. The blood samples were used to isolate the causative agent for detection viral RNA further expression recombinant protein as primary antibody. spleen kidneys was characterize antigen...
Enhanced recovery after surgery (ERAS) is a multiprofessional, multidisciplinary and evidence‐based program that aims to reduce complications, improve overall prognosis, shorten hospital stays, promote fast following major surgery. Nurses play crucial role in the successful implementation of ERAS program. Therefore, this research focuses on trajectory optimized acquired by nurses enhanced elderly patients undergoing radical for lung cancer. This study concludes proposed preoperative...
A. baumannii is an important and common clinical pathogen, especially in the intensive care unit (ICU). This study aimed to characterize one hypervirulent strain a patient with community-acquired pneumonia herpes simplex type 1 virus infection.
Objective: To explore the clinical value of static and dynamic magnetic resonance imaging (MRI) in evaluating effect electrical stimulation combined with biofeedback treatment pelvic organ prolapse postpartum. Methods: A total 50 primiparas diagnosed as postpartum from February 2016 to November 2017 were randomly divided into group (24 cases) control (26 cases). The recovered spontaneously, received electric therapy (6 weeks). All subjects underwent MRI before after treatment. thickness...
Background The diagnostic value of virtual imaging combined with three-dimensional computed tomographic angiography (3D-CTA) for intracranial aneurysms has not been fully elucidated yet. This study aimed to evaluate the application techniques and 3D-CTA in diagnosing patients aneurismal subarachnoid hemorrhage (SAH) at acute stage. Methods Eighty non-traumatic SAH received examinations. raw CT data these were reconstructed transferred into 3D mode through surgical plan system based on...
Abstract Background To explore the kinetic changes in virology, specific antibody response and imaging during clinical course of COVID-19. Methods This observational study enrolled 20 patients with COVID-19, who were hospitalized between January 20–April 6, 2020, two COVID-19 designated hospitals Zhoushan, Zhejiang Rushan, Shandong, China, The laboratory findings, imaging, serum to viral infection, RNA level throat stool samples assessed from onset recovery phase Results SARS-COV-2 was...
Objective@#Comparing the benefit of Abidor, lopinavir/ritonavir and recombinant interferon α-2b triple combination antiviral therapy dual to hospitalized novel coronavirus pneumonia 2019 in Zhejiang province.@*Methods@#A multi-center prospective study was carried out compare effect with 15 medical institutions Province. All patients were treated (5 million U, 2 times/d) aerosol inhalation. 196 abidol (200 mg, 3 + lopinavir / ritonavir (2 tablets, 1 time/12 h) as treatment group. 41 The who...
Abstract Background Severe fever and thrombocytopenia bunyavirus (SFTSV) infection causes severe syndrome with high mortality. It is extremely rare that a transmitting tick can be directly captured in bite wounds, SFTSV isolated from both the patient’s serum to establish solid pathogen diagnosis. Case presentation We report case infected bunyavirus. The 69-year-old male patient presented tenderness on two lymph nodes right groin. A visible mark appeared upper quadrant of abdomen, live was...
To explore the effect of cytoplasmic DNA sensor DAI on replication hepatitis B virus (HBV) and its possible mechanism.The hepatocyte-derived cell line HepG2 was co-transfected with siRNA HBV1.3 replicative plasmid PHY106, cells were divided into two experimental groups. Six hours later, total RNA extracted from first group expression IFIT1 IL-6 detected by real-time RT-PCR. The second incubated for 4 days, after which supernatant collected HBV surface antigen (HBsAg) envelope (HBeAg) ELISA....