A5045390769- Evolution and Paleontology Studies
- Animal Ecology and Behavior Studies
- Bat Biology and Ecology Studies
- Physiological and biochemical adaptations
- Wildlife Ecology and Conservation
- Animal Behavior and Reproduction
- Circadian rhythm and melatonin
- Primate Behavior and Ecology
- Neuroendocrine regulation and behavior
- Plant and animal studies
- Evolutionary Game Theory and Cooperation
- Genetic diversity and population structure
- Neurobiology and Insect Physiology Research
- Hypothalamic control of reproductive hormones
- Parasite Biology and Host Interactions
- Genetics, Aging, and Longevity in Model Organisms
- Animal Behavior and Welfare Studies
- Vector-borne infectious diseases
- Amphibian and Reptile Biology
- Pleistocene-Era Hominins and Archaeology
- Mitochondrial Function and Pathology
- Mollusks and Parasites Studies
- Adipose Tissue and Metabolism
- Sleep and Wakefulness Research
- Morphological variations and asymmetry
University of Pretoria
2016-2025
Parliament of United Kingdom
2025
Bristol-Myers Squibb (United States)
2023
University of Oxford
2023
Novo Nordisk (United Kingdom)
2023
Queen Mary University of London
2023
Google (United States)
2022
King Saud University
2012-2021
AgResearch
2021
The University of Queensland
2009-2020
Safe anaerobic metabolism Naked mole-rats live in large colonies deep underground hypoxic conditions. Park et al. found that these animals fuel glycolysis with fructose by a rewired pathway avoids tissue damage (see the Perspective Storz and McClelland). These results provide insight into adaptations this strange social rodent has to make for life underground. They also have implications medical practice, particularly understanding how protect tissues from hypoxia. Science , issue p. 307 ; see 248
Preface Acknowledgements 1. Introduction to the Bathyergidae 2. The subterranean niche 3. food resource of African Mole-Rats 4. Social organisation in 5. Life history patterns and reproductive biology 6. suppression reproduction 7. genetic structure Mole-Rat populations 8. evolution sociality on References Index.
In many animal societies, dominant individuals monopolize reproduction, but the tactics they employ to achieve this are poorly understood. One possibility is that aggressive dominants render their subordinates infertile by inducing chronic physiological "stress." However, hypothesis has been discarded largely for cooperatively breeding species, where reproductive monopolies often extreme. Here we provide strong support stress-related suppression in a cooperative mammal, meerkat (Suricata...
Abstract Aging, often considered a result of random cellular damage, can be accurately estimated using DNA methylation profiles, the foundation pan-tissue epigenetic clocks. Here, we demonstrate development universal pan-mammalian clocks, 11,754 arrays from our Mammalian Methylation Consortium, which encompass 59 tissue types across 185 mammalian species. These predictive models estimate age with high accuracy ( r > 0.96). Age deviations correlate human mortality risk, mouse somatotropic...
Using DNA methylation profiles (
The African mole–rats (family Bathyergidae) are subterranean hystricomorph rodents occurring in a variety of habitats and displaying levels sociality which range from solitary to eusocial, making them unique mammalian taxonomic group test ecological influences on sociality. Here, we use an extensive DNA–based phylogeny comparative analysis investigate the relationship between ecology, evolution within family. Mitochondrial cytochrome–b 12s rRNA trees reveal that species monophyletic when...
Journal Article The Social Structure and Reproductive Biology of Colonies the Mole-Rat, Cryptomys damarensis (Rodentia, Bathyergidae) Get access Nigel C. Bennett, Bennett Zoology Department, University Cape Town, Rondebosch, 7700, South Africa Search for other works by this author on: Oxford Academic Google Scholar Jennifer U. M. Jarvis Mammalogy, Volume 69, Issue 2, 20 May 1988, Pages 293–302, https://doi.org/10.2307/1381379 Published: 1988 history Received: 18 August 1986 Accepted: 28 1987
Accelerometers are powerful sensors in many bio-logging devices, and increasingly allowing researchers to investigate the performance, behaviour, energy expenditure even state, of free-living animals. Another sensor commonly used animal-attached loggers is magnetometer, which has been primarily dead-reckoning or inertial measurement tags, but little outside that. We examine potential magnetometers for helping elucidate behaviour animals a manner analogous to, very different from,...
Population viability is driven by individual survival, which in turn depends on individuals balancing energy budgets. As carnivores may function close to maximum sustained power outputs, decreased food availability or increased activity render some populations energetically vulnerable. Prey theft compromise energetic budgets of mesopredators, such as cheetahs and wild dogs, are susceptible competition from larger carnivores. We show that daily expenditure (DEE) was similar size-based...
ABSTRACT Aging is often perceived as a degenerative process resulting from random accrual of cellular damage over time. Despite this, age can be accurately estimated by epigenetic clocks based on DNA methylation profiles almost any tissue the body. Since such pan-tissue have been successfully developed for several different species, we hypothesized that one build pan-mammalian measure in all mammalian species. To address generated data using 11,754 arrays, each profiling up to 36 thousand...
Naked mole-rats (Heterocephalus glaber) form some of the most cooperative groups in animal kingdom, living multigenerational colonies under control a single breeding queen. Yet how they maintain this highly organized social structure is unknown. Here we show that common naked mole-rat vocalization, soft chirp, used to transmit information about group membership, creating distinctive colony dialects. Audio playback experiments demonstrate individuals make preferential vocal responses home...
An ex vivo preparation was developed to record from single sensory fibres innervating the glabrous skin of mouse forepaw. The density mechanoreceptor innervation forepaw found be three times higher than that hindpaw skin. Rapidly adapting mechanoreceptors innervate Meissner's corpuscles were severalfold more responsive slowly moving stimuli in compared those We a distinct group small hairs centre exclusively innervated by directionally sensitive D-hair receptors. directional sensitivity, but...
Abstract The naked mole-rat Heterocephalus glaber is a eusocial mammal exhibiting extreme longevity (37-year lifespan), extraordinary resistance to hypoxia and absence of cardiovascular disease. To identify the mechanisms behind these exceptional traits, metabolomics RNAseq cardiac tissue from mole-rats was compared other African genera (Cape, Cape dune, Common, Natal, Mahali, Highveld Damaraland mole-rats) evolutionarily divergent mammals (Hottentot golden mole C57/BL6 mouse). We metabolic...
In animal social groups, socially subordinate individuals frequently show low reproductive success or completely fail to breed. This suppression of reproduction is currently typically attributed control by dominant individuals. However, subordinates in cooperative groups often lack access unrelated mates, and an alternative possibility that their limited inbreeding avoidance. Using the eusocial Damaraland mole–rat Cryptomys damarensis, this paper provides first experimental evidence, our...