A5100717948- RNA modifications and cancer
- Lung Cancer Treatments and Mutations
- Asian Culture and Media Studies
- Prostate Cancer Treatment and Research
- Sarcoma Diagnosis and Treatment
- Chinese history and philosophy
- Cancer Cells and Metastasis
- RNA Interference and Gene Delivery
- Cell Adhesion Molecules Research
- Ubiquitin and proteasome pathways
- FOXO transcription factor regulation
- Japanese History and Culture
- Bioactive Compounds and Antitumor Agents
- Diverse Topics in Contemporary Research
- Metastasis and carcinoma case studies
- Psychosocial Factors Impacting Youth
- Cancer therapeutics and mechanisms
- Asian American and Pacific Histories
- Job Satisfaction and Organizational Behavior
- Estrogen and related hormone effects
- Synthesis of heterocyclic compounds
- Advanced Breast Cancer Therapies
- Liver Disease Diagnosis and Treatment
- Calcium signaling and nucleotide metabolism
- Medicinal Plants and Bioactive Compounds
Sungkyunkwan University
2015-2024
Samsung Medical Center
2024
CHA Bundang Medical Center
2022-2023
CHA University
2022-2023
Pusan National University Hospital
2022
Zhejiang University
2021
Kangbuk Samsung Hospital
2015-2019
Yonsei University
2018
Ulsan College
2015
Kyung Hee University
2015
This study was designed to investigate the antitumor mechanism of Phytol in hepatocellular carcinomas including Huh7 and HepG2 cells association with caspase dependent apoptosis epithelial mesenchymal transition (EMT) signaling. significantly suppressed viability cells. Also, increased sub G1 population terminal deoxynucleotidyl transferase deoxyuridine triphosphate nick end labeling (TUNEL) positive a concentration manner Consistently, cleaved poly (adenosine diphosphate‐ribose) polymerase...
Although intestinal fibrosis is a consequence of recurrent inflammation in Inflammatory bowel disease (IBD), alleviating alone does not prevent the progression fibrosis, suggesting that development direct anti-fibrotic agents necessary. This study aimed to evaluate properties combination treatment with pentoxifylline (PTX) and vitamin E (Vit-E) on human primary myofibroblasts (HIMFs) therapeutic potential therapy murine models IBD.HIMFs were pretreated PTX, Vit-E, or both, incubated TGF-β1....
Endometriosis is a gynecological disease prevalent in women of reproductive age, and it characterized by the ectopic presence growth eutopic endometrium. The pathophysiology diagnostic biomarkers endometriosis have not yet been comprehensively determined. To discover molecular markers pathways underlying pathogenesis endometriosis, we identified differentially expressed genes (DEGs) three Gene Expression Omnibus microarray datasets (GSE11691, GSE23339, GSE7305) performed gene set enrichment...
Androgen receptor (AR) is involved in the development and progression of prostate cancers. However, mechanisms by which this occurs remain incompletely understood. In previous reports, chicken ovalbumin upstream promoter-transcription factor II (COUP-TF II) has been suggested to play a role present study, we explored putative COUP-TF cancers investigating its effect on cell proliferation cross-talk between AR. Overexpression results inhibition androgen-dependent cancer cells. Further studies...
The basic leucine zipper transcription factor, CCAAT enhancer-binding protein-alpha (C/EBPalpha), negatively regulates cell proliferation and induces terminal differentiation of various types. C/EBPalpha is expressed in the prostate, but its potential role tissue unknown. Herein, we show that highly at stage growth arrest during prostate development. Furthermore, overexpression decreases rate DNA synthesis LNCaP cancer cells. Investigation cross-talk between androgen receptor (AR)...
Osteosarcoma is the most common malignant bone tumor in children and adolescents. This aggressive cancer mostly occurs long bones. Therefore, novel therapeutic approaches, such as biological therapies gene therapy, are required to efficiently treat osteosarcoma. Capsaicin (trans‑8‑methyl‑N‑vanillyl‑6‑nonenamide) has been demonstrated inhibit growth of several types cells a number studies have shown that osteosarcoma may be vulnerable therapies. However, little known regarding effects...
Purpose In response to the challenges and difficulties imposed by rare cancers, multi-stakeholder initiatives dedicated improving cancer care was launched, several recommendations were made professional societies. However, these primarily reflect view of advocates supporters, may not represent views "average" clinician or researcher. this study, we sought investigate perceived with regard potential solutions endorsed oncologists. Materials Methods A representative sample 420 oncologists...
Early-stage hepatocellular carcinoma (HCC) is still difficult to cure for its high recurrence rate. This study aimed examine whether glycemic burden management could be one way improve outcomes of early-stage HCC. A total 137 very early or HCC patients who underwent resection ablation at Samsung Medical Center and had assessment were analyzed. Glycemic was assessed using hemoglobin A1c (HbA1c) level. Outcomes overall survival. Risks survival compared according a cut-off point 6.5% two points...
Globus is often linked with gastroesophageal reflux disease, which influences its treatment strategies. This study aimed to investigate clinical characteristics of patients refractory proton pump inhibitor (PPI) globus better understand etiology.
The study examines the depression of older adults with level depressive symptoms in Korean (N = 319) who have cancer and are currently receiving treatment. Level was measured using version Center for Epidemiologic Studies Depression Scale (K-CES-D). Other factors under consideration were socio-demographic variables (gender, age, education, living spouse, perceived economic status), cancer/treatment (cancer stage at diagnosis, number treatment, recurrence, functional capability), internal...
This research examines how employees respond to leader-member exchange (LMX) ambivalence formed through interaction with their leaders. Drawing upon attachment theory, the purpose of this is examine LMX has an effect on employees’ creative performance via psychological states (i.e., safety and trust in leader). In addition, power distance orientation examined as a moderating factor that weakens negative relationship between states, thereby influencing performance. Data were collected from...
Supplementary Figures 1-4, Tables 1-4 from Inhibition of ALK, PI3K/MEK, and HSP90 in Murine Lung Adenocarcinoma Induced by <i>EML4-ALK</i> Fusion Oncogene
Supplementary Methods and Legends from Inhibition of ALK, PI3K/MEK, HSP90 in Murine Lung Adenocarcinoma Induced by <i>EML4-ALK</i> Fusion Oncogene
Supplementary Methods and Legends from Inhibition of ALK, PI3K/MEK, HSP90 in Murine Lung Adenocarcinoma Induced by <i>EML4-ALK</i> Fusion Oncogene
Imagining Beyond the Here and Now in Margaret Cho's I'm One that I Want Hyun Joo Lee (bio) In her memoir, stand-up comedienne Cho writes parents had to deal with immigration difficulties San Francisco of 1960s, portraying them era their lives as “not being hippies, LBJ, men on moon, having first child while totally unprepared for reality.”1 Cho’s description parents’ situation suggests near absence Asian Americans, active participants public culture, popular imagination 1960s 1970s; American...