Diego Cugola

ORCID: 0000-0001-9921-4612
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About
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Research Areas
  • Cardiac Valve Diseases and Treatments
  • Infective Endocarditis Diagnosis and Management
  • Cardiac Imaging and Diagnostics
  • Orthopedic Infections and Treatments
  • Cardiac Structural Anomalies and Repair
  • Cardiovascular Function and Risk Factors
  • Cardiac pacing and defibrillation studies
  • Pericarditis and Cardiac Tamponade
  • Aortic Disease and Treatment Approaches
  • Mechanical Circulatory Support Devices
  • Cardiac Arrhythmias and Treatments
  • Infectious Aortic and Vascular Conditions
  • Streptococcal Infections and Treatments
  • Pleural and Pulmonary Diseases
  • Sepsis Diagnosis and Treatment
  • Thermal Regulation in Medicine
  • Cardiovascular Effects of Exercise
  • Acute Myocardial Infarction Research
  • Surgical site infection prevention
  • Coronary Interventions and Diagnostics
  • Transplantation: Methods and Outcomes
  • Renal function and acid-base balance
  • Antimicrobial Resistance in Staphylococcus
  • Cardiac, Anesthesia and Surgical Outcomes
  • Atrial Fibrillation Management and Outcomes

Ospedale Papa Giovanni XXIII
2014-2024

Montreal Heart Institute
2020

Lung Institute
2018

Université Laval
2018

Deleted Institution
2018

Fondazione Lanza
2018

Harefield Hospital
2018

Istituto Mediterraneo per i Trapianti e Terapie ad Alta Specializzazione
2018

Bristol Royal Infirmary
2018

University of Bristol
2018

InvestigatorsIMPORTANCE Postpericardiotomy syndrome, postoperative atrial fibrillation (AF), and effusions may be responsible for increased morbidity health care costs after cardiac surgery.Postoperative use of colchicine prevented these complications in a single trial.OBJECTIVE To determine the efficacy safety perioperative oral reducing postpericardiotomy AF, pericardial or pleural effusions. DESIGN, SETTING, AND PARTICIPANTSInvestigator-initiated, double-blind, placebo-controlled,...

10.1001/jama.2014.11026 article EN JAMA 2014-08-30

Biochemical and cytological pericardial fluid (PF) analysis is essentially based on the knowledge of pleural composition. The aim present study to identify reference intervals (RIs) for PF according state-of-art methodological standards.We prospectively collected analysed venous blood consecutive subjects undergoing elective open-heart surgery from July 2017 October 2018. Exclusion criteria enrolment were evidence diseases at preoperatory workup or intraoperatory assessment, any other...

10.1136/heartjnl-2020-317966 article EN Heart 2020-11-11

The aim of this multicentre study is to report the clinical experiences all patients undergoing transcatheter aortic valve implantation (TAVI) with a balloon-expandable device in Italy.The Italian Transcatheter balloon-Expandable Registry (ITER) real-world registry that includes who have undergone TAVI Sapien (Edwards Lifesciences, Irvine, CA, USA) bioprosthesis Italy since it became available practice. From 2007 2012, 1904 were enrolled undergo 33 centres. Outcomes classified according...

10.1093/ejcts/ezw218 article EN European Journal of Cardio-Thoracic Surgery 2016-07-12

Heart transplantation (HTx) in patients with complex congenital heart disease (CHD) is a challenge because of structural anomalies and multiple previous procedures. We analysed our results adult paediatric to evaluate outcome assess risk factors affecting mortality.Between 1985 2011, among 839 who underwent HTx, 85 received for end-stage CHD. Patients were divided into four age subgroups: <1 year (8 patients, Group I), 1-10 years (20 II), 11-18 (24 III) >18 (33 IV) two time periods:...

10.1093/ejcts/ezs350 article EN European Journal of Cardio-Thoracic Surgery 2012-06-24

We described clinical-epidemiological features of prosthetic valve endocarditis (PVE) and assessed the determinants early surgical outcomes in multicentre design.Data regarding 2823 patients undergoing surgery for at 19 Italian Centers between 1979 2015 were collected a database. Of them, 582 had PVE: this group, mortality complications assessed, also taking into account different chronological eras encompassed by study.Overall hospital (30-day) was 19.2% (112 patients). Postoperative any...

10.1093/ejcts/ezx045 article EN European Journal of Cardio-Thoracic Surgery 2017-02-15

Bone wax is the substance which has been used for hemostasis in different surgical fields up to one hundred years and historically our center prevent sternal bleeding subsequent complications. Recently, reabsorbable gelatin powder come into use. Up now there are no clinical studies that compare these two substances. Between 1st January 31st December 2004, 1249 patients have operated on cardiac procedures center, of them 557 were enrolled a randomized perspective monocentric study. They...

10.1510/icvts.2005.126250 article EN Interactive Cardiovascular and Thoracic Surgery 2006-10-17

In patients with ischemic mitral regurgitation requiring valve replacement (MVR), the choice of prosthesis type is crucial. The exercise hemodynamic and functional capacity performance in contemporary prostheses have never been investigated. To compare between biological (MVRb) mechanical (MVRm) prostheses.We analyzed 86 consecutive who underwent MVRb (n=41) or MVRm (n=45) coronary artery bypass grafting. All preoperative resting echocardiography 6-minute walking test. At follow-up, stress...

10.1161/circheartfailure.117.004056 article EN Circulation Heart Failure 2018-01-01

Stroke incidence after transcatheter aortic valve implantation (TAVI) still represents a concern. This multicentre study aimed at investigating the hypothesis that CHADS2 and CHA2DS2-VASc scores may be used to predict perioperative stroke TAVI. The Italian Transcatheter Balloon-Expandable Valve Implantation Registry (ITER) is multicentre, prospective registry of patients undergoing balloon-expandable TAVI using Edwards Sapien XT prosthesis between 2007 2012. primary end-point this was 30-day...

10.1093/ejcts/ezw199 article EN European Journal of Cardio-Thoracic Surgery 2016-06-28

The most commonly used accesses for transcatheter aortic valve implantation (TAVI) are the transfemoral (TF-TAVI) and transapical (TA-TAVI) ones. There concerns about TA-TAVI use in patients with reduced left ventricular ejection fraction (LVEF). aim of this retrospective multicentre study was to compare outcomes TF-TAVI poor LVEF. Patients LVEF ≤35% were included analysis. Data obtained from Italian Transcatheter Balloon-Expandable Registry (ITER), which enrolled undergoing TAVI Sapien...

10.1093/ejcts/ezx227 article EN European Journal of Cardio-Thoracic Surgery 2017-06-03

Aims Limited information is available on number and type of cells present in the pericardial fluid (PF). Current evidence has been garnered with inaccurate application guidelines for analysis body fluids. This study was aimed at investigating performance automate cytometric PF adult subjects. Methods Seventy-four consecutive samples were analysed Sysmex XN a module (XN-BF) optical microscopy (OM). The also encompassed assessment limit blank, detection quantitation (LoQ), imprecision,...

10.1136/jclinpath-2019-205788 article EN Journal of Clinical Pathology 2019-04-29

Abstract OBJECTIVES Endocarditis after the Bentall procedure is a severe disease often complicated by pseudoaneurysm or mediastinitis. Reoperation challenging but conservative therapy not effective. The aim of this study was to assess short- and midterm outcomes patients reoperated on for Bentall-related endocarditis. METHODS Seventy-three with procedure-related endocarditis were recorded in Italian registry. mean age 57 ± 14 years 92% men; preoperative comorbidities included hypertension...

10.1093/ejcts/ezaa136 article EN European Journal of Cardio-Thoracic Surgery 2020-04-09

Background and Aim: Infective endocarditis (IE) is a serious disease, in many cases, surgery necessary. The aim of the present study to quantify differences long-term survival recurrence after mitral valve replacement (MVR) for IE according prosthesis type among patients aged 40 70 years. Methods: This was an analysis INFECT- REGISTRY. Trends proportion use mechanical prostheses versus biological ones over time were tested. Confounders adjusted using doubly robust method that combines...

10.2459/01.jcm.0001096128.27258.02 article EN Journal of Cardiovascular Medicine 2024-11-01

Background: Recent trials showed that TAVI is neither inferior nor superior to surgical aortic valve replacement. The aim of this study was evaluate the outcomes Sutureless and Rapid Deployment Valves (SuRD-AVR) when compared in low risk patients with isolated stenosis. Methods: Data from five European Centers were retrospectively collected. We included 1306 consecutive at (EUROSCORE II &lt; 4) who underwent replacement by means SuRD-AVR (n = 636) or 670) 2014 2019. A 1:1 nearest-neighbor...

10.3390/jcm12124045 article EN Journal of Clinical Medicine 2023-06-14

Background: Infective endocarditis (IE) is a serious disease, and in many cases, surgery necessary. Whether the type of prosthesis implanted for aortic valve replacement (AVR) IE impacts patient survival matter debate. The aim present study to quantify differences long-term recurrence AVR according among patients aged 40 65 years. Methods: This was an analysis INFECT-REGISTRY. Trends proportion use mechanical prostheses versus biological ones over time were tested by applying sieve...

10.3390/jcm13010153 article EN Journal of Clinical Medicine 2023-12-27

Background: Infective endocarditis(IE) is a serious disease and in many cases surgery necessary. Whether the type of prosthesis implanted for aortic valve replacement(AVR) IE impacts patient survival matter debate. The aim present study to quantify differences long-term survival, recurrence endocarditis AVR according among patients aged 40 65 years. Methods: This was an analysis INFECT-REGISTRY. Overall, 4365 were diagnosed operated on from 2000 2021. Of these, 549 between years underwent...

10.20944/preprints202311.0661.v1 preprint EN 2023-11-09

The aim of this study is to compare outcomes patients undergoing surgical ventricular reconstruction (SVR) with normothermic cardiopulmonary bypass (CPB) and beating heart or hypothermic CPB cardioplegic arrest. Between 2001 2008, 588 underwent SVR. A propensity score matching was performed 91 matched pairs were created: group 1 (G1) operated beating-heart technique, 2 (G2) Mean age 62+/-9 years in G1 63+/-10 G2 [not significant (NS)]. Average follow-up 42.7+/-26 months (range 1-72). Major...

10.1510/icvts.2009.222919 article EN Interactive Cardiovascular and Thoracic Surgery 2010-01-14

We report the case of a 51-year-old woman, treated with radiotherapy at age two years, for pulmonary sarcoma. Subsequently she developed severe aortic stenosis and bilateral ostial coronary artery disease, symptomatic dyspnea (NYHA III functional class). Due to prohibitive surgical risk, underwent successful stenting in right left main ostia drug eluting stents and, afterwards, transcatheter valve replacement transfemoral implantation 23 mm Edwards SAPIEN XT valve. The percutaneous treatment...

10.1155/2015/851624 article EN cc-by Case Reports in Cardiology 2015-01-01

To compare early and late mortality of acute isolated tricuspid valve infective endocarditis (TVIE) treated with repair or replacement.Patients who were surgically for TVIE from 1983 to 2018 retrieved the Italian Registry Surgical Treatment Valve Prosthesis Infective Endocarditis. All patients followed up by means phone interview calling patient referral physicians cardiologists. Kaplan-Meier method was used assess survival free recurrence log-rank test univariate comparison. The primary end...

10.2459/jcm.0000000000001310 article EN Journal of Cardiovascular Medicine 2022-05-30

Background/IntroductionConstrictive pericarditis causes progressively impaired diastolic filling of the heart with associated symptoms failure.High pressure in right atrium creates high hepatic venous subsequent impairment liver function.Hepatic function has been proposed as an indirect index cardiac failure constrictive pericarditis.A non-invasive monitoring system, "The LIMON test", developed to measure indocyanine green elimination (ICG) by pulse spectrophotometry.Indocyanine clearance...

10.1186/1749-8090-10-s1-a37 article EN cc-by Journal of Cardiothoracic Surgery 2015-12-01
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