A5100758128- Cancer Cells and Metastasis
- Estrogen and related hormone effects
- Cancer-related molecular mechanisms research
- HER2/EGFR in Cancer Research
- Thyroid Cancer Diagnosis and Treatment
- Bioinformatics and Genomic Networks
- Ferroptosis and cancer prognosis
- Cancer Research and Treatments
- Metal complexes synthesis and properties
- Ferrocene Chemistry and Applications
- Diet and metabolism studies
- Plant and Fungal Interactions Research
- NF-κB Signaling Pathways
- Wnt/β-catenin signaling in development and cancer
- Breast Cancer Treatment Studies
- Cytokine Signaling Pathways and Interactions
- Climate Change and Health Impacts
- Cancer Treatment and Pharmacology
- Click Chemistry and Applications
- Genomics, phytochemicals, and oxidative stress
- Urinary and Genital Oncology Studies
- Neurofibromatosis and Schwannoma Cases
- BRCA gene mutations in cancer
- Cellular Mechanics and Interactions
- Male Breast Health Studies
Inner Mongolia Medical University
2013-2024
Guangxi Medical University
2018-2024
Jiangsu Cancer Hospital
2019-2020
Nanjing Medical University
2014-2020
General Hospital of Shenyang Military Region
2018-2019
West Virginia University
2017
Wenzhou Medical University
2014
First Affiliated Hospital of Wenzhou Medical University
2014
The First Affiliated Hospital, Sun Yat-sen University
2012
Sun Yat-sen University
2012
Exposure to cold weather is associated with infaust cardiovascular responses, including myocardial infarction and arrhythmias. However, the exact mechanisms of these adverse changes in myocardium under stress are unknown. This study was designed investigate cardiac injury induced by mice. The mice were randomly divided into three groups, normal control (no handling), 1-week 2-week stress. We observed physiological morphological tissues, we measured 3′-nitrotyrosine 4-hydroxynonenal,...
Non-small cell lung cancer (NSCLC) is the leading cause of cancer-related death. This study aimed to examine roles DHRS4-AS1/miR-224-3p signaling in stemness NSCLC. Real-time PCR showed that DHRS4-AS1 was downregulated cancerous tissues, and bioinformatics analysis revealed high expression indicated a good prognosis for NSCLC patients. Sphere colony formation assays overexpression significantly suppressed stem cell-like properties. also abrogated OCT4, SOX2, CD34, CD133, markedly inhibited...
Abstract Background Hepatocellular carcinoma (HCC) remains one of the most common cancers worldwide and tends to be detected at an advanced stage. More effective biomarkers for HCC screening prognosis assessment are needed mechanisms require further exploration. The role MAOA in has not been intensively investigated. Methods In‐house tissue microarrays, genechips, RNAsequencing datasets were integrated explore expression status clinical value HCC. Immunohistochemical staining was utilized...
Betacellulin (BTC), a member of the epidermal growth factor (EGF) family, binds and activates ErbB1 ErbB4 homodimers. BTC was expressed in tumors involved tumor progression. CXCL8 (interleukin-8) cell proliferation via transactivation receptor (EGFR). The present study designed to investigate possible interrelation between human lung cancer cells (A549) demonstrated mechanisms intracellular signals regulation both functions. Bio-behaviors A549 were assessed using Cell-IQ Alive Image...
Papillary thyroid cancer (PTC) is the most common subtype of cancer, and inflammation relates significantly to its initiation prognosis. Systematic exploration immunogenomic landscape therein assist in PTC prognosis therefore urgent. The Cancer Genome Atlas (TCGA) project provides a large number genetic samples that enable comprehensive reliable study. Hence, we integrated expression profiles immune-related genes (IRGs) progression-free intervals (PFIs) survival 493 patients based on TCGA...
To observe the protective effects of modified Linggui Zhugan Decoction combined with short-term very low calorie diets (VLCDs) on cardiovascular risk factors in obese patients impaired glucose tolerance (IGT). Eighty-five IGT spleen hypofunction and dampness accumulation type were randomly divided into treated group (n=45) control (n=40). The was given VLCDs. basic weight-reduction treatment. total course 6 months. Changes fasting plasma (FPG), 2-hour postprandial blood (2hPG), glycosylated...
Objective: The study aimed to explore the efficacy of pharmacokinetic-based 5-fluorouracil dose management by plasma concentration test in advanced colorectal cancer treatment. Methods: 153 samples patients were enrolled and randomly assigned a control group an experimental group. All received double-week chemotherapy with 5- fluorouracil (four weeks used as one period), duration ranged from 2 6 periods. In first period, all administered classic strategy body surface area (BSA). Results:...
Abstract There are only nine primitive neuroectodermal tumor (PNET) cases that have arisen in lung parenchyma without pleural or chest wall involvement the literature. Here, we present a long–term survival case of pulmonary PNET. A mass was detected 19-year-old man on radiograph and computed tomography image. At three-year follow-up, had enlarged diameter by two-fold. The lesion resected via lower left lobectomy. Histologically, composed uniform cells with round nuclei scanty cytoplasm...
Objective At present, the structure of knowledge in field childhood thyroid cancer is not clear enough, and scholars lack a sufficient understanding developing trends this field, which has led to shortage forward-looking outputs. The purpose research help construct complete framework identify current challenges, opportunities, development trends. Methods We searched literature Web Science Core Collection database on August 7, 2023 extracted key information from top 100 most cited articles,...
The diagnostic utility of SRY-box transcription factor 10 (SOX10) expression in basal-like breast cancer (BLBC) has been reported previously. However, the effect SOX10 on malignancy BLBC cells and underlying molecular mechanisms remain unelucidated. Here, we investigate regulatory roles progression.Sequencing data from patients with were extracted Cancer Genome Atlas database to determine transcriptomic levels across subtypes. Subsequently, bioinformatics relevance was investigated....
Objective To develop a new type of blast injury simulator to establish mouse model brain and study its damage mechanism. Methods Thirty healthy Kunming mice were randomly(random number) divided into the normal control group (TBI) group. A traumatic was prepared by self-developed explosive simulator. Morris water maze, Evans blue experiment HE staining used observe effects shockwave exposure on spatial memory, blood-brain barrier, pathological changes tissues. T test for statistical...