A5048081915- Ovarian cancer diagnosis and treatment
- Intraperitoneal and Appendiceal Malignancies
- Neuroendocrine Tumor Research Advances
- Colorectal and Anal Carcinomas
- Pancreatitis Pathology and Treatment
- Pancreatic and Hepatic Oncology Research
- Gastric Cancer Management and Outcomes
- Prostate Cancer Diagnosis and Treatment
- Colorectal Cancer Screening and Detection
- Molecular Biology Techniques and Applications
- Bladder and Urothelial Cancer Treatments
- Hepatocellular Carcinoma Treatment and Prognosis
- Cancer Diagnosis and Treatment
- Helicobacter pylori-related gastroenterology studies
- Ovarian function and disorders
- Colorectal Cancer Surgical Treatments
- Radiomics and Machine Learning in Medical Imaging
- Garlic and Onion Studies
- Salivary Gland Tumors Diagnosis and Treatment
- Appendicitis Diagnosis and Management
- Urinary and Genital Oncology Studies
- Cancer and Skin Lesions
- Orthopaedic implants and arthroplasty
- Kidney Stones and Urolithiasis Treatments
- AI in cancer detection
The Ohio State University
2021-2025
The Ohio State University Wexner Medical Center
2020-2024
The Ohio State University Comprehensive Cancer Center – Arthur G. James Cancer Hospital and Richard J. Solove Research Institute
2021-2022
We compiled two cohorts of colorectal adenosquamous carcinoma (ASC) to describe its histologic and molecular aspects using modern parameters compare them with literature reports meta-analysis individual case series. identified 53 ASC from 19 North American academic medical centres, in addition national database on 94 Dutch cases. analysed available clinical, histologic, immunohistochemical features patient outcome. comprised 0.02% cancers the database. The median cohort ages at resection...
Risk stratification of gastrointestinal stromal tumors (GISTs) is based on experience with the stomach, small bowel, and rectum, which are far more common than GISTs other sites. In this study from 47 institutions, we analyzed esophagus (n = 102), colon 136), appendix 27) for their size, mitotic rate, morphology, outcome to determine criteria predict behavior. Esophageal were (median: 2.5 cm) spindle cell morphology a low rate (mean: 3.6/5 mm2). Twelve (12%) progressed, including 11 >5/5 mm2...
Malignant struma ovarii is an exceedingly rare pathology with a paucity of established criteria regarding management and surveillance recommendations largely based on case reports retrospective data. Many authors have supported stratification malignant into low vs high-risk disease more conservative reserved for those deemed low-risk. Here we present unique recurrent metastatic after was undertaken in the setting initially low-risk disease.
Universal tumor screening (UTS) for Lynch syndrome (LS) on colorectal cancer (CRC) can be performed biopsies or resection specimens. The advantage of is the chance to provide preoperative genetic counseling/testing (GC/T) so patients diagnosed with LS make informed decisions regarding extent. We evaluated utilization UTS biopsies, percentage deficient mismatch repair (dMMR) who underwent GC/T preoperatively, and whether surgical/treatment were impacted. a retrospective review medical records...
Prostate cancer (PCa) is the most common noncutaneous in men Western world. In addition to accurate diagnosis, Gleason grading and tumor volume estimates are critical for patient management. Computer-aided detection (CADe) software can be used facilitate diagnosis improve diagnostic accuracy reporting consistency. However, preanalytical factors such as fixation staining of prostate biopsy specimens whole slide images (WSI) on scanners vary significantly between pathology laboratories may,...
Epithelioid hemangioendothelioma (EHE) is a rare low-grade malignant vascular tumor with indolent biology, characterized by reciprocal t(1;3)(p36.6;q25) resultant WWTR1::CAMTA1 gene fusion in the vast majority of cases, regardless anatomic location. Only small subset, exhibiting well formed vasoformative features will contain YAP1::TFE3 fusion. Primary intranodal EHE exquisitely rare. We report case 54-year-old male persistent left groin mass discomfort for nine months. A CT abdomen and...
With advancements in the field of digital pathology, there has been a growing need to compare diagnostic abilities pathologists using digitized whole slide images against those when traditional hematoxylin and eosin (H&E)-stained glass slides for primary diagnosis. One most common specimens received pathology practices is an endoscopic gastric biopsy with request rule out Helicobacter pylori (H. pylori) infection. The current standard care identification organisms on H&E-stained slides....
Microscopic findings in key tissues are often critical to determine the cause of death medical autopsies.The overall quality histologic sections depends on numerous pre-analytic factors, among which tissue section size and thickness.We designed a prospective improvement study whether simple intervention formalin pre-fixation myocardium, liver, kidney could improve ease cutting autopsy as assessed by histotechnicians pathologists.Of 46 autopsies included study, 21 were randomly assigned...
Villous adenomas arising within intestinal metaplasia (IM) of the urinary tract are exceedingly rare with only 20 cases reported in literature. Histologically most IM do not have cytological atypia; however, can show dysplastic changes ranging from low-grade to high-grade as seen gastrointestinal tract. We report a case villous adenoma, background cystitis cystica, occurring bladder neck 48-year-old male history end-stage renal disease, secondary hyperparathyroidism, and kidney stones who...
Abstract Extra-axial ependymoma is a rare neoplasm. Reported anatomic sites include the ovary, para-ovarian tissues, pelvis, paracervical soft tissue, lung, omentum, small bowel, and posterior mediastinum. Primary peritoneal ependymomas are extremely rare. We report such an example in 58-year-old woman who presented with abdominal pain, bloating, history of 70-lb weight loss over prior year. Computed tomography scan showed 20-cm pelvic mass extending into abdomen 3.5-cm peritoneal-based...