A5038599317- Animal Nutrition and Physiology
- Insect and Pesticide Research
- Meat and Animal Product Quality
- Plant and animal studies
- Insect and Arachnid Ecology and Behavior
- Livestock and Poultry Management
- Genetic and phenotypic traits in livestock
- Insect-Plant Interactions and Control
- Peroxisome Proliferator-Activated Receptors
- Bee Products Chemical Analysis
- Heat shock proteins research
- RNA and protein synthesis mechanisms
- Circular RNAs in diseases
- Genetic diversity and population structure
- Identification and Quantification in Food
- Nanoparticle-Based Drug Delivery
- Advanced biosensing and bioanalysis techniques
- Surfactants and Colloidal Systems
- Advanced Polymer Synthesis and Characterization
- Proteins in Food Systems
- Silkworms and Sericulture Research
- thermodynamics and calorimetric analyses
- Advanced Cellulose Research Studies
- Ferroptosis and cancer prognosis
- Cytokine Signaling Pathways and Interactions
ZheJiang Academy of Agricultural Sciences
2013-2025
Animal Science Research Institute
2012-2025
Shanghai Ocean University
2022-2025
Ministry of Agriculture and Rural Affairs
2022-2025
Zhejiang University
2012-2025
Affiliated Hospital of Jiangsu University
2023-2024
Jiangsu University
2023-2024
Animal Husbandry & Veterinary
2023
Fudan University
2019-2020
Zhongshan Hospital
2020
Compact CRISPR/Cas9 systems that can be packaged into an adeno-associated virus (AAV) hold great promise for gene therapy. Unfortunately, currently available small Cas9 nucleases either display low activity or require a long protospacer adjacent motif (PAM) sequence, limiting their extensive applications. Here, we screened panel of and identified ortholog from Staphylococcus auricularis (SauriCas9), which recognizes simple NNGG PAM, displays high genome editing, is compact enough to AAV...
Rising temperatures are severely affecting the mortality, laying performance, and meat quality of duck. Our aim was to investigate effect acute heat stress on expression shock proteins (HSPs: HSP90, 70, 60, 40, 10) inflammatory factors (nitric oxide synthase (iNOS), cyclooxygenase-2 (COX-2)) antioxidant enzyme activity (superoxide dismutase (SOD), malondialdehybe (MDA), catalase (CAT), total capacity (T-AOC)) in livers ducks compare thermal tolerance Pekin Muscovy exposed stress. Ducks were...
Geese were domesticated over 6,000 years ago, making them one of the first poultry. are capable rapid growth, disease resistance, and high liver lipid storage capacity, can be easily fed coarse fodder. Here, we sequence analyze whole-genome an economically important goose breed in China compare it with that terrestrial bird species.A draft whole-goose genome was obtained by shotgun sequencing, 16,150 protein-coding genes predicted. Comparative genomics indicate significant differences occur...
The widespread use of fungicides for plant protection has increased the potential pollinator exposure. This study therefore aimed at assessing acute and chronic effects on pollinators. For this purpose, oral toxicity common azoxystrobin, pyraclostrobin, boscalid to Eastern honeybee Apis cerana cerena was first evaluated, multiple aspects were investigated after exposure a one-tenth medium lethal dose (LD50) 10 days. revealed that LD50 values pyraclostrobin adult honeybees 12.7 μg/bee, 36.6...
In this paper, the effect of soybean isolate protein (SPI) content on physicochemical properties and oxidative stability chitosan–sodium tripolyphosphate (CS-STPP)-loaded fish oil capsules was investigated. The SPI/CS-STTP formed after addition different amounts SPI were larger in size more homogeneous morphology than CS-STPP capsules, encapsulated surface CS matrix, altering particles. study CS-to-SPI blend ratios (1:0, 3:1, 2:1, 1:1, 1:2) showed that water microcapsules increased from...
Got a crush: Native cellulose can be dispersed as nanofibers in organic solvents by ball milling with esterification agents. Milling hexanoyl chloride/DMF gives hexanoyl-coated dispersible several solvents. succinic anhydride/DMSO results water-dispersible nanofibers. The open the way to new mechanochemistries. Detailed facts of importance specialist readers are published "Supporting Information". Such documents peer-reviewed, but not copy-edited or typeset. They made available submitted...
The self-assembly and pH- thermo-sensitivities properties of hydroxypropyl cellulose-graft-poly(N,N-dimethyl aminoethyl methacrylate) (HPC-g-PDMAEMA) copolymers in aqueous solutions were investigated by transmittance, dynamic light scattering (DLS), 1H NMR spectroscopy. Micelles with different structure can be formed varying either pH value or temperature. At low pH, e.g., 3.0, the HPC backbone copolymer collapse to form core micelles stabilized protonated PDMAEMA side chains on surface upon...
A new type of cellulose derivative was synthesized by means conjugating cysteamine to hydroxypropyl (HPC) and the degree thiol groups could be controlled feed ratio reactants. The thiolated HPC (HPC–SH) maintains thermosensitivity on chain can oxidized disulfide bonds. Cytotoxity tests performed MG-63 cells proved that HPC–SH is not harmful cells. Nanogels fabricated self-association HPC–HS in solution at 45 °C then oxidation bonds occurs stabilize associated structure. crosslinking nanogels...
The behavioural transition from nurses to foragers in honey bees is known be affected by intrinsic and extrinsic factors, including colony demography, hormone levels, brain chemistry structure, gene expression the brain. However, molecular mechanism underlying this of still obscure.Through RNA sequencing, we performed a comprehensive analysis lncRNAs mRNAs bee foragers. Nurses both typical colonies single-cohort were used prepare six libraries generate 49 100 million clear reads per sample....
Long non-coding RNAs (lncRNAs) are emerging as critical regulators in honeybee physiology, influencing development, behavior, and stress responses. This study investigates the role of lncRNA LOC113219358 immune response neurophysiological regulation Apis mellifera brains. Using RNA interference (RNAi) sequencing (RNA-seq), we demonstrate that silencing lncLOC113219358 significantly alters expression 162 mRNA transcripts, including genes associated with detoxification, energy metabolism,...
There is a growing risk of pollinators being exposed to multiple fungicides due the widespread use for plant protection. A safety assessment honeybees commonly used urgently required. Therefore, acute oral toxicity ternary mixed fungicide ABP (azoxystrobin: boscalid: pyraclostrobin = 1:1:1, m/m/m) was tested on (Apis cerana cerana), and its sublethal effect foragers' guts evaluated. The results showed that median lethal concentration (LD50) foragers 12.6 μg a.i./bee. caused disorder...
The Pekin duck, bred from the mallard (Anas platyrhynchos) in china, is one of most famous meat duck species world. However, it more sensitive to heat stress than Muscovy which believed have originated South America. With temperature raising, mortality, laying performance, and quality are severely affected. This study aims uncover temperature-dependent proteins two using comparative proteomic approach. Duck was cultured under 39°C ± 0.5°C for 1 h, then immediately returned 20°C a 3 h...
Abstract Compared to commercial chickens, local breeds exhibit better in meat quality and flavour, but the productivity (e.g., growth rate, body weight) of chicken is rather low. Genetic analysis based on whole-genome sequencing contributes elucidating genetic markers or putative candidate genes related some economic traits, facilitating improvement production performance, acceleration breeding progress, conservation resources. Here, a total 209 chickens from 13 were investigated,...
Abstract Background Indigenous chickens were developed through a combination of natural and artificial selection; essentially, changes in genomes led to the formation these modern breeds via admixture events. However, their confusing genetic backgrounds include genomic footprint regulating complex traits, which is not conducive animal breeding. Results To better evaluate candidate regions under domestication indigenous chickens, we considered both runs homozygosity (ROHs) selective...
Graphene oxide quantum dots (GOQDs) have attracted substantial attention in numerous fields due to their unique physicochemical properties. However, nanotoxicity and potential for use biomedicine still require further study. In this work, the effects of GOQD trans- 10-hydroxy-2-decenoic acid (10-HDA) cotreatment on immune function macrophages (RAW264.7 cells) were investigated. particular, LC/MS-based metabolomics was performed evaluate GOQDs metabolism LPS-stimulated macrophages. Herein, we...
Due to the inferior shelf life of meat products without undergoing autoclaving treatment and limitation a single preservation technique, joint effects ultrasound modified atmosphere packaging (MAP) on cold storage sauced ducks at 4 °C were investigated in this study. The results showed that growth rate total viable count deterioration physicochemical parameters (thiobarbituric acid reactive substances, pH, volatile basic nitrogen) duck could be inhibited by (28 kHz, 450 W, 30 min) MAP (30%...
High temperature is a major abiotic stress limiting animal growth and productivity worldwide. The Muscovy duck (Cairina moschata), sometimes called the Barbary drake, type of with fairly unusual domestication history. In Southeast Asia, meat one top meats consumed, as such, production an important topic research. transcriptomic genomic data presently available are insufficient to understanding molecular mechanism underlying heat tolerance ducks. Thus, transcriptome expression profiling for...
Background. Recent experimental studies have shown that vegetable oil supplementation ameliorates high-fat diet- (HFD-) induced hyperlipidemia and oxidative stress in mice via modulating hepatic lipid metabolism the composition of gut microbiota. The aim this study was to investigate efficacy Torreya grandis kernel (TKO) rich unpolysaturated fatty acid against gain a deep insight into its potential mechanisms. Methods. Normal were randomly divided three groups: ND (normal diet), LO diet...
Honeybees (Apis mellifera) are critical to maintaining ecological balance and important pollinators. The oviposition behavior in honeybees is complex. Circular RNAs (circRNAs) found form circRNA-miRNA crosstalk play roles reproduction processes. Here, dual luciferase reporter was used confirm the between ame_circ_2015 ame_miR-14-3p. Functional experiments vitro vivo were performed investigate biological functions of egg-laying queens. results showed that directly target ame_miR-14-3p,...