- Diet and metabolism studies
- Nutrition, Genetics, and Disease
- Obesity, Physical Activity, Diet
- Nutritional Studies and Diet
- Eating Disorders and Behaviors
- Obesity and Health Practices
- Adipose Tissue and Metabolism
- Genetic Associations and Epidemiology
- Mobile Health and mHealth Applications
- Cardiovascular Disease and Adiposity
- Consumer Attitudes and Food Labeling
- Insect and Arachnid Ecology and Behavior
- Neurobiology and Insect Physiology Research
- Dietary Effects on Health
- Plant Parasitism and Resistance
- Health and Medical Studies
- Diet, Metabolism, and Disease
- Regulation of Appetite and Obesity
- Advanced MRI Techniques and Applications
- Metabolomics and Mass Spectrometry Studies
- Birth, Development, and Health
- Thermoregulation and physiological responses
- COVID-19 and Mental Health
- Virtual Reality Applications and Impacts
- Impact of Technology on Adolescents
Technical University of Munich
2016-2025
University of Oregon
2001-2025
Fulda University of Applied Sciences
2023-2025
Klinikum rechts der Isar
2015-2024
Helmholtz Zentrum München
2008-2022
München Klinik
2013-2022
Fresenius (Germany)
2010-2020
Fresenius Medical Care (Germany)
2019
Else Kröner-Fresenius-Stiftung
2012
Center for Environmental Health
2009-2012
Obesity is recognised as a global epidemic and the most prevalent metabolic disease world-wide. Specialised obesity services, however, are not widely available in Europe, care can vary enormously across European regions. The Association for Study of (EASO, www.easo.org) has developed these criteria to form pan-European network accredited EASO-Collaborating Centres Management (EASO-COMs) accordance with accepted academic guidelines. This will include university, public private clinics ensure...
Article25 September 2012Open Access Novel biomarkers for pre-diabetes identified by metabolomics Rui Wang-Sattler Corresponding Author Research Unit of Molecular Epidemiology, Helmholtz Zentrum München, Neuherberg, Germany Search more papers this author Zhonghao Yu Christian Herder German Diabetes Center, Institute Clinical Diabetology, Leibniz Center at Heinrich Heine University, Düsseldorf, Ana C Messias Structural Biology, Anna Floegel Department Human Nutrition Potsdam-Rehbruecke,...
To date, all altered patterns of seasonal interactions observed in insects, birds, amphibians, and plants associated with global warming during the latter half 20th century are explicable as variable expressions plastic phenotypes. Over last 30 years, genetically controlled photoperiodic response pitcher-plant mosquito, Wyeomyia smithii , has shifted toward shorter, more southern daylengths growing seasons have become longer. This shift is detectable over a time interval short 5 years....
Introduction. Previous studies identified genetic links between the TCF7L2 C/T variant rs7903146, type 2 diabetes (T2D), and obesity. We wished to deepen our understanding of how specific diets interact with this affect blood metabolites, an aspect not previously investigated. Hence, we conducted a controlled study where individuals different genotypes followed Mediterranean (Med) or low-fat (LF) diet for one week. Methods. Participants were recruited from Boston, MA (USA) area....
<b><i>Objective: </i></b>The human serum metabolite profile is reflective of metabolic processes, including pathophysiological changes characteristic diseases. Therefore, investigation concentrations in obese children might give new insights into biological mechanisms associated with childhood obesity. <b><i>Methods: </i></b>Serum samples 80 and 40 normal-weight between 6 15 years age were analyzed using a mass spectrometry-based metabolomics...
Abstract Background Metabolomics helps to identify links between environmental exposures and intermediate biomarkers of disturbed pathways. We previously reported variations in phosphatidylcholines male smokers compared with non-smokers a cross-sectional pilot study small sample size, but knowledge the reversibility smoking effects on metabolite profiles is limited. Here, we extend our metabolomics large prospective including female quitters. Methods Using targeted approach, quantified 140...
OBJECTIVE Metformin is used as a first-line oral treatment for type 2 diabetes (T2D). However, the underlying mechanism not fully understood. Here, we aimed to comprehensively investigate pleiotropic effects of metformin. RESEARCH DESIGN AND METHODS We analyzed both metabolomic and genomic data population-based KORA cohort. To evaluate effect metformin on metabolite concentrations, quantified 131 metabolites in fasting serum samples multivariable linear regression models three independent...
Abstract The aim of the study was to investigate prevalence of, and attitudes toward, vegetarianism veganism. We also assessed association between vegetarianism/veganism eating disorder, depressive, somatic symptoms. A cross-sectional questionnaire survey in adults Germany that representative terms age, gender, educational level carried out. Data from 2449 (53.5% females) were included. Mean age 49.6 (SD 17.1) years. total 5.4% participants reported following a vegetarian or vegan diet....
Objective: Long-term positive energy balance promotes the development of obesity, a main risk factor for type 2 diabetes mellitus (T2DM). While an association between increased resting metabolic rate (RMR) and insulin sensitivity (IS) was shown previously, underlying mechanisms remain unclear. Aim mediator analysis to investigate role inflammation within RMR IS. Methods: Anthropometric, clinical, lifestyle data were collected according standard operating procedures. measured using indirect...
The public restrictions taken during the COVID-19 pandemic have substantially affected lifestyle and health behavior of children adolescents. In Germany, little is known how these changes influenced daily life in families with adolescents.A cross-sectional survey was performed April/May 2022 across similar to a 2020. Parents (N = 1,004, 20-65 years) at least one child aged 3-17 years filled an online questionnaire released by Forsa Institute for Social Research Statistical Analysis. Fifteen...
Abstract Background Despite an increasing number of smartphone applications (apps) addressing weight management, data on the effect app-based multimodal obesity treatment approaches loss is limited. This study aimed to examine a digital intervention program delivered by app body in persons with obesity. Methods For this single-centre randomized controlled study, 168 adults mass index (BMI) between 30.0 and 40.0 kg/m 2 without severe comorbidities were recruited region Munich into two groups....
Abstract Understanding how life is adapting to urban environments represents an important challenge in evolutionary biology. Here we investigate a widely cited example of adaptation, Culex pipiens form molestus , also known as the London Underground Mosquito. Population genomic analysis ∼350 contemporary and historical samples counter popular hypothesis that originated belowground less than 200 years ago. Instead, show first adapted human aboveground Middle East over course >1000 years,...