A5100342171- Immune cells in cancer
- Advanced Image and Video Retrieval Techniques
- Hepatocellular Carcinoma Treatment and Prognosis
- Network Traffic and Congestion Control
- Zoonotic diseases and public health
- Nanoplatforms for cancer theranostics
- Digital Imaging for Blood Diseases
- Immune Response and Inflammation
- Visual Attention and Saliency Detection
- Mosquito-borne diseases and control
- Mesenchymal stem cell research
- Mobile Agent-Based Network Management
- Image Enhancement Techniques
- Advanced Glycation End Products research
- Urinary and Genital Oncology Studies
- Cancer, Hypoxia, and Metabolism
- Phytochemistry and Bioactivity Studies
- Cancer Mechanisms and Therapy
- Fatty Acid Research and Health
- Cancer Cells and Metastasis
- Aortic Disease and Treatment Approaches
- Atherosclerosis and Cardiovascular Diseases
- Angiogenesis and VEGF in Cancer
- Macrophage Migration Inhibitory Factor
- Diabetes, Cardiovascular Risks, and Lipoproteins
Southwest Medical University
2021-2025
Macau University of Science and Technology
2021-2025
Affiliated Hospital of Southwest Medical University
2020-2025
Shaoxing People's Hospital
2025
Hangzhou Normal University
2023
Jiangsu Institute of Parasitic Diseases
2017-2023
University of Macau
2022
Zhejiang University
2019
Dalian Medical University
2019
Chongqing Medical University
2019
Tumor-associated macrophages (TAMs) play an important role in the progression and prognostication of numerous cancers. However, clinical significance TAM markers oral squamous cell carcinoma (OSCC) has not been elucidated. The present study was designed to investigate correlation between expression pathological features OSCC by tissue microarray. Tissue microarrays containing 16 normal mucosa, 6 epithelial dysplasia, 43 specimens were studied immunohistochemistry. We observed that protein...
Camouflaged object detection is a challenging task that aims to identify objects having similar texture the surroundings. This paper presents amplify subtle difference between camouflaged and background for by formulating multiple texture-aware refinement modules learn features in deep convolutional neural network. The module computes biased co-variance matrices of feature responses extract information, adopts an affinity loss set parameter maps help separate background, leverages...
Recent studies have shown that the non-enzymatic function of CD73 plays a key role in tumor progression, but this pancreatic cancer cells has not been studied. Furthermore, little is known about mechanism involved regulation tumors. Here, we found expression was upregulated ductal adenocarcinoma (PDAC) and its correlated with poor prognosis. knockdown inhibited cell growth induced G1 phase arrest via AKT/ERK/cyclin D signaling pathway. We also necrosis factor receptor (TNFR) 2 CD73-induced...
Abstract Background Brain impairment is one of a major complication diabetes. Dietary flavonoids have been recommended to prevent brain damage. Astragalus membranaceus herbal medicine commonly used relieve the complications Flavonoids ingredients membranaceus, but its function and mechanism on diabetic encepholopathy still unknown. Methods Type 2 diabetes mellitus (T2DM) model was induced by high fat diet STZ in C57BL/6J mice, BEnd.3 HT22 cell lines were applied vitro study. Quality...
Transarterial chemoembolization (TACE) is commonly used for treating advanced hepatocellular carcinoma (HCC). However, the instability of lipiodol-drug emulsion and altered tumor microenvironment (TME, such as hypoxia-induced autophagy) postembolization are responsible unsatisfactory therapeutic outcomes. Herein, pH-responsive poly(acrylic acid)/calcium phosphate nanoparticles (PAA/CaP NPs) were synthesized carrier epirubicin (EPI) to enhance efficacy TACE therapy through autophagy...
Clear cell (glycogen-rich) urothelial carcinoma is an exceedingly rare variant of invasive carcinoma, distinguished by the presence abundant cytoplasmic glycogen, which imparts a clear appearance to tumor cells under histological examination. In this case report, diagnosis was established through histopathological evaluation with hematoxylin and eosin (HE) staining, immunohistochemical analysis, identification significant glycogen accumulation. The patient, 89-year-old male, admitted on July...
Introduction Cigarette smoking extract (CSE) can cause endothelial cell (EC) dysfunction, and then promote the occurrence development of atherosclerosis. However, molecular mechanisms underlying CSE-induced EC dysfunction are unknown. Sirt1, as a deacetylase, is involved in various biological processes ECs. Therefore, this study investigated whether CSE induces apoptosis mitochondrial human umbilical vein cells (HUVECs) via Sirt1-dependent mechanisms. Methods HUVEC activity was assessed...
Camouflaged object detection is a challenging task that aims to identify objects having similar texture the surroundings. This paper presents amplify subtle difference between camouflaged and background for by formulating multiple texture-aware refinement modules learn features in deep convolutional neural network. The module computes covariance matrices of feature responses extract information, designs an affinity loss set parameter maps help separate background, adopts boundary-consistency...
In liver transplant cases, severe hepatic ischemia/reperfusion injury (HIRI) is a strong predictor of adverse graft and overall outcomes. During HIRI, high‐mobility group box 1 (HMGB1) promotes hepatocellular death proinflammatory cytokine secretion by toll‐like receptor 4 (TLR4). Because salicylates inhibit HMGB1/TLR4 interaction, we hypothesized that may ameliorate HIRI‐induced damage inhibiting axis activation. Using murine model found the salicylate acetyl‐3‐aminoethyl salicylic acid...
Advanced glycation end products (AGEs) have been widely regarded as an important inducing factor in the pathogenesis of diabetic arteriosclerosis, and proliferation migration vascular smooth muscle cells (VSMCs) are also involved this process. However, it is not clear whether AGEs promote atherosclerosis by VSMCs. To figure out question, study investigated effects on human aorta (HASMCs) underlying mechanisms. This evaluated different concentrations cell migration. CCK8, transwell, western...
Airway inflammation and remodeling are critical pathological changes in asthma, macrophage activation plays a vital role this process. Sirtuin 1 (SIRT1) reduces airway by affecting macrophages asthma. This study aimed to investigate the potential benefit underlying mechanism of SIRT1 agonist bergenin as treatment for We performed vivo vitro experiments establishing Sirt1fl/fl-LysMcre mouse asthma model using alveolar macrophage-like cell line MH-S, respectively. Our results show that...
The hepatic VX2 carcinoma model in rabbits has been widely used interventional diagnosis and treatment research for hepatocellular (HCC). However, traditional methods developing this all have their shortcomings.To develop an improved method to construct animal of carcinoma.The puncture technique was obtain the tumor tissue. A puncture-inoculation kit designed modified implant tissue into recipient rabbit's liver.18 New Zealand white were implanted with using under ultrasound guidance....
Operation management platform (OMP) is the hotspot of research for prototype ForCES routers. This paper presents an analysis and evaluation message transmission mechanism in OMP. First, we construct experimental environment analyze some commonly-used mechanisms on Web application. Furthermore, according to main requirements characteristics messages OMP routers at present, adopt http object stream socket implementation have carried out experiment compare performance with socket. Results show...
The next generation networks demand the router to be more open, flexible and programmable. As an important part of ForCES software, extensible LFB management development model based on software was illustrated, which enhances extensibility software. In this paper structure first discussed. Based that, some key technologies were discussed for implementation model, including resources construction data, registration function so on. This compares two methods about LFB-resources registration....
Abstract Diabetes is a serious global health challenge that affects millions of people worldwide. One major complication diabetic foot ulcer (DFU), leading to decreased quality life and increased mortality in patients. The underlying mechanism DFU not completely understood. involved wound healing diabetes was studied vivo vitro. Gain-and loss-of function studies were performed study the roles WDR74 TGF-β play DFU. M1 M2 macrophage phenotypic marker, extracellular matrix (ECM) components,...
Objective To analyze the results of assessment malaria elimination in 8 counties (districts) Huai'an City, Jiangsu Province, so as to provide evidences for consolidating achievement elimination. Methods The data from network reports epidemic situation, blood examinations febrile patients, epidemiological questionnaires cases, investigation and disposal focuses were collected analyzed City 2010 2016. on clinicians'ability diagnosis treatment well inspectors'skill Plasmodium microscopic...