A5029879298- Bacteriophages and microbial interactions
- Genetic and phenotypic traits in livestock
- Developmental Biology and Gene Regulation
- Marine Bivalve and Aquaculture Studies
- Nanoplatforms for cancer theranostics
- Insect-Plant Interactions and Control
- Ion channel regulation and function
- Lipid metabolism and disorders
- Aquaculture disease management and microbiota
- Hydrology and Watershed Management Studies
- Pluripotent Stem Cells Research
- Aquaculture Nutrition and Growth
- Plant tissue culture and regeneration
- Land Use and Ecosystem Services
- Neuroendocrine Tumor Research Advances
- Wnt/β-catenin signaling in development and cancer
- Insect Resistance and Genetics
- Viral Infectious Diseases and Gene Expression in Insects
- Plant Virus Research Studies
- Tissue Engineering and Regenerative Medicine
- Aquatic life and conservation
- Fish Ecology and Management Studies
- Ion Channels and Receptors
- Livestock Farming and Management
- Vagus Nerve Stimulation Research
Southwest Medical University
2021-2025
Wuhan University
2011-2024
Guangdong Academy of Medical Sciences
2013-2024
Guangdong Provincial People's Hospital
2020-2024
Southern Medical University
2024
Renmin Hospital of Wuhan University
2020-2024
Gansu Agricultural University
2020-2021
Cardiovascular Institute of the South
2020
Stanford University
2020
Hebei North University
2020
In skeletal myoblasts, Ras has been considered to be a strong inhibitor of myogenesis. Here, we demonstrate that is involved also in the chemotactic response myoblasts. Expression dominant-negative mutant inhibited chemotaxis C2C12 myoblasts basic fibroblast growth factor (bFGF), hepatocyte (HGF), and insulin-like 1 (IGF-1), key regulators limb muscle development regeneration. A Ral decreased migration by these factors, while inhibitors for phosphatidylinositol 3-kinase mitogen-activated...
Introduction Cigarette smoking extract (CSE) can cause endothelial cell (EC) dysfunction, and then promote the occurrence development of atherosclerosis. However, molecular mechanisms underlying CSE-induced EC dysfunction are unknown. Sirt1, as a deacetylase, is involved in various biological processes ECs. Therefore, this study investigated whether CSE induces apoptosis mitochondrial human umbilical vein cells (HUVECs) via Sirt1-dependent mechanisms. Methods HUVEC activity was assessed...
Amphioxus is a best candidate for studying the evolutionary and developmental mechanisms of vertebrates, because its vertebrate-like but much simpler morphology, embryonic development genome structure. Producing live amphioxus embryos throughout year an ideal comparative evolution studies. However, all species have distinct breeding seasons in wild laboratory. We recently found that Chinese B. belcheri could reproduce repeatedly beyond natural season when reared under proper conditions. In...
Preventing surgical site infections (SSIs) of implants has drawn significant attention in both basic and clinical research. Implants with convenient preparation methods intelligent drug release capabilities are highly needed to resist bacterial infection. Herein, we designed an drug-release system, which can be instantly incorporated during the process. The system involves β-glycerophosphate (β-GP) chitosan (CS) as a thermosensitive hydrogel for instant construction onto hyaluronic acid (HA)...
Abstract The lancelet is considered to be a promising laboratory model animal. To establish colonies of lancelet, we collected parental lancelets Branchiostoma belcheri and B. japonicum (previously named as tsingtauense ) with fully developed gonads from Xiamen Rare Marine Creature Conservation Areas (Fujian, China) on dates just before their spawning in the field 2005. Those spawned spontaneously produced thousands upon fertilized eggs. After carefully hatching maintaining for almost 1...
Abstract Background Elevated lipoprotein(a) [Lp(a)] levels predict cardiovascular events incidence in patients with coronary artery disease (CAD). Genetic variants the rs3798220, rs10455872 and rs6415084 single-nucleotide polymorphisms (SNPs) Lp(a) gene ( LPA ) correlate elevated levels, but whether these SNPs have prognostic value for CAD is unknown. The present study evaluated association of subsequent after percutaneous intervention (PCI). Methods TaqMan SNP genotyping assays were...
Abstract Precision-cut lung slices (PCLS) are ideal for measuring small airway contraction. However, these measurements currently limited to acute exposure scenarios that typically last a few minutes hours. Using an insulin-supplemented culture medium, we prolong the contractility in mouse PCLS up two weeks. Compared conventional medium provides no additional benefit preserving cellular viability or structure. it protects smooth muscle (ASM) against loss of myosin heavy chain (SMMHC)...
The heterogeneity nature of sepsis is significantly impacted by the site infection. This study aims to explore predictive value multiple scoring systems in assessing prognosis septic patients across different infection sites. Data for this retrospective cohort were extracted from Medical Information Mart Intensive Care IV database (MIMIC-IV) (v2.2). Adult meeting criteria 3.0 and admitted intensive care unit (ICU) enrolled. Infection sites included pneumonia, urinary tract (UTI), cellulitis,...
The efficacy of tree injected with emamectin benzoate (EB) against the Asian long-horned beetle (ALB) was tested in a heavily infested willow forest Beijing, China. In 1.7-ha plot, 240 out 310 trees were treated two EB formulations at various rates. After fall application, larval population decreased by 89% following spring and >99% during second year detected monitoring new frass emission from marked holes. Consequently, number exit holes emerging adults to 0 year. Re-infestation occurred...
Ridge-furrow rainwater harvesting (RFRH) is known to be effective in controlling water loss and soil erosion, increasing moisture crop yield semiarid regions. However, it can cause waterlogging, ridge overtopping, harvest failure if not properly designed. A four consecutive-year field trial was carried out assess the impacts of various slope gradients tillage practices on moisture, runoff, sediment yield, associated nutrient losses, fodder use efficiency (WUE) alfalfa Loess Plateau, China....
We tested the hypothesis that retinal blood flow has a postocclusive reactive hyperemia response modulated by occlusion duration and metabolic activity, choroidal does not.Anesthetized paralyzed rats (n = 34) were studied. Retinal was measured laser speckle imaging Doppler flowmetry, respectively. Blood oxygenation level-dependent functional magnetic resonance (BOLD fMRI) used to measure changes in relative of circulations. Transient carotid elicited with hydraulic occluder on common artery....
The Wnt/β-catenin signaling pathway plays a crucial role in the embryonic development of metazoans. Although has been studied extensively many model animals, its function amphioxus, most primitive chordate, remains largely uncharacterized. To obtain basic data for functional analysis, we identified and isolated seven genes (Lrp5/6, Dvl, APC, CkIα, CkIδ, Gsk3β, Gro) from amphioxus (Branchiostoma floridae) genome. Phylogenetic analysis revealed that had fewer members each gene family than...