- Glycosylation and Glycoproteins Research
- Carbohydrate Chemistry and Synthesis
- Enzyme Production and Characterization
- Adsorption and biosorption for pollutant removal
- Plant tissue culture and regeneration
- Transgenic Plants and Applications
- Phosphorus and nutrient management
- Wastewater Treatment and Nitrogen Removal
- Galectins and Cancer Biology
- Coagulation and Flocculation Studies
- Proteoglycans and glycosaminoglycans research
- Surfactants and Colloidal Systems
- Minerals Flotation and Separation Techniques
- Nanomaterials for catalytic reactions
- Polysaccharides and Plant Cell Walls
- Genomics and Phylogenetic Studies
- Polysaccharides Composition and Applications
- Viral Infectious Diseases and Gene Expression in Insects
- Escherichia coli research studies
- Geochemistry and Elemental Analysis
- Microbial Metabolic Engineering and Bioproduction
- Pancreatic function and diabetes
- vaccines and immunoinformatics approaches
- Xenotransplantation and immune response
- International Business and FDI
Shandong University
2014-2025
Qilu University of Technology
2022
State Council of the People's Republic of China
2021
State Key Laboratory of Microbial Technology
2007-2019
Hebei University of Engineering
2016
Guangxi University
2015
The Ohio State University
2007-2010
California Institute of Technology
2010
Howard Hughes Medical Institute
2010
Daqing Oilfield General Hospital
2008
Introducing structural modifications into biomolecules represents a powerful approach to dissect their functions and roles in biological processes. Bacterial polysaccharides, despite rich information essential bacterium-host interactions bacterial virulence, have largely been unexplored for vivo modifications. In this study, we demonstrate the incorporation of panel monosaccharide analogs polysaccharides highly homogenous manner via metabolic engineering promiscuous sugar nucleotide...
Nucleotide sugars (NSs) are essential building blocks for the enzymatic assembly of glycans. In this study, we established a preparation and recycling avenue to biocatalysts synthesis NSs. This approach involves fusing two enzymes into bifunctional chimera using elastin‐like polypeptides (ET64) as purification tag, which allows easy recovery these without need chromatography. We successfully constructed obtained five fusion (GalK‐USP‐ET64, GlmU‐NahK‐ET64, ManC‐NahK‐ET64, FKP‐ET64,...
Aldo-keto reductases (AKRs) are a superfamily of enzymes that reduce aldehydes and ketones, have broad range substrates. An AKR gene, sakR1, was identified in the cyanobacterium Synechococcus sp. PCC 7002. A mutant strain with sakR1 inactivated sensitive to glycerol, carbon source can support heterotrophic growth It found null accumulated more toxic methylglyoxal than wild-type when glycerol added medium, suggesting SakR1 is involved detoxification methylglyoxal, highly metabolite damage...