Péter Nagy

ORCID: 0000-0002-0256-3304
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About
Contact & Profiles
Research Areas
  • Attention Deficit Hyperactivity Disorder
  • Obsessive-Compulsive Spectrum Disorders
  • Autism Spectrum Disorder Research
  • Bipolar Disorder and Treatment
  • Child and Adolescent Psychosocial and Emotional Development
  • Williams Syndrome Research
  • Body Image and Dysmorphia Studies
  • Children's Physical and Motor Development
  • Neural and Behavioral Psychology Studies
  • Anxiety, Depression, Psychometrics, Treatment, Cognitive Processes
  • Functional Brain Connectivity Studies
  • Suicide and Self-Harm Studies
  • Eating Disorders and Behaviors
  • Pharmaceutical studies and practices
  • COVID-19 and Mental Health
  • Genomic variations and chromosomal abnormalities
  • Cognitive Abilities and Testing
  • Peripheral Neuropathies and Disorders
  • Genomics and Chromatin Dynamics
  • Soil Moisture and Remote Sensing
  • Emergency and Acute Care Studies
  • Child Nutrition and Feeding Issues
  • Adolescent and Pediatric Healthcare
  • RNA Interference and Gene Delivery
  • Genetics and Neurodevelopmental Disorders

Vadaskert Alapítvány a Gyermekek Lelki Egészségéért
2015-2024

Bethesda Gyermekkórház
2021-2024

Feinstein Institute for Medical Research
2023

Schneider Children's Medical Center
2021

University College London
2021

University of Calgary
2021

Tel Aviv University
2021

Stanley Foundation
2019

Massachusetts General Hospital
2019

Broad Institute
2019

Patients with attention-deficit/hyperactivity disorder (ADHD) are at an increased risk of attempting suicide. Stimulants, such as methylphenidate hydrochloride, the most common treatment for ADHD, but association between their therapeutic use and suicide is unclear.To investigate attempts.A population-based, electronic medical records database from Hong Kong Clinical Data Analysis & Reporting System was used to identify 25 629 individuals aged 6 years who were treated January 1, 2001,...

10.1001/jamapsychiatry.2017.2183 article EN JAMA Psychiatry 2017-07-26

<h3>Background</h3> Gilles de la Tourette Syndrome is a neurodevelopmental disorder that caused by the interaction of environment with complex genetic background. The etiology remains, so far, elusive, although multiple promising leads have been recently reported. recent implication histamine decarboxylase (<i>HDC</i>) gene, key enzyme in production, raises intriguing hypothesis possible role histaminergic dysfunction leading to TS onset. <h3>Methods</h3> Following up on finding nonsense...

10.1136/jmedgenet-2013-101637 article EN Journal of Medical Genetics 2013-07-03

Between 2019 and 2022, there was a marked rise in adolescents/young adults seeking urgent help for functional tic-like behaviours (FTLBs). Given the global scale of this phenomenon, we aimed to pool cases from different institutions an international registry better characterize spectrum facilitate future longitudinal observation.An collaborative group 10 tertiary referral centres tic disorders collected retrospective data on FTLB patients who sought specialists' attention between last...

10.1111/ene.15611 article EN European Journal of Neurology 2022-10-25

To compare psychiatric emergencies and self-harm at emergency departments (EDs) 1 year into the pandemic, to early pandemic pre-pandemic, examine changes in characteristics of presentations.This retrospective cohort study expanded on Pandemic-Related Emergency Psychiatric Presentations (PREP-kids) study. Routine record data March April 2019, 2020, 2021 from 62 EDs 25 countries were included. ED presentations made by children adolescents for any mental health reasons analyzed.Altogether,...

10.1016/j.jaac.2022.11.016 article EN cc-by Journal of the American Academy of Child & Adolescent Psychiatry 2023-02-16

The aim of this study was to compare the efficacy and safety prodrug psychostimulant lisdexamfetamine dimesylate (LDX) non-stimulant noradrenergic compound atomoxetine (ATX) in children adolescents with attention-deficit/hyperactivity disorder (ADHD) who had previously responded inadequately methylphenidate (MPH). This 9-week, head-to-head, randomized, double-blind, active-controlled (SPD489-317; ClinicalTrials.gov NCT01106430) enrolled patients (aged 6–17 years) at least moderately...

10.1007/s40263-013-0104-8 article EN cc-by-nc CNS Drugs 2013-08-19
Fotis Tsetsos Dongmei Yu Jae Hoon Sul Alden Y. Huang Cornelia Illmann and 95 more Lisa Osiecki Sabrina M. Darrow Matthew E. Hirschtritt Erica Greenberg Kirsten Müller‐Vahl Manfred Stuhrmann Yves Dion Guy A. Rouleau H.N. Aschauer M. Stamenković Monika Schlögelhofer Paul Sandor Cathy L. Barr Marco A. Grados Harvey S. Singer Markus M. Nöthen Johannes Hebebrand Anke Hinney Robert A. King Thomas Fernandez Csaba Barta Zsanett Tárnok Péter Nagy Christel Depienne Yulia Worbe Andreas Hartmann Cathy L. Budman Renata Rizzo Gholson J. Lyon William M. McMahon James R. Batterson Daniëlle C. Cath Irene A. Malaty Michael S. Okun Cheston M. Berlin Douglas W. Woods Paul C. Lee Joseph Jankovic Mary M. Robertson Donald L. Gilbert Lawrence W. Brown Barbara J. Coffey Andrea Dietrich Pieter J. Hoekstra Samuel Kuperman Samuel H. Zinner Michael Wagner James A. Knowles A. Jeremy Willsey Jay A. Tischfield Gary A. Heiman Nancy J. Cox Nelson B. Freimer Benjamin M. Neale Lea K. Davis Giovanni Coppola Carol A. Mathews Jeremiah M. Scharf Peristera Paschou Cathy L. Barr James R. Batterson Cheston M. Berlin Cathy L. Budman Daniëlle C. Cath Giovanni Coppola Nancy J. Cox Sabrina M. Darrow Lea K. Davis Yves Dion Nelson B. Freimer Marco A. Grados Erica Greenberg Matthew E. Hirschtritt Alden Y. Huang Cornelia Illmann Robert A. King Roger Kurlan James F. Leckman Gholson J. Lyon Irene A. Malaty Carol A. Mathews William M. McMahon Benjamin M. Neale Michael S. Okun Lisa Osiecki Mary M. Robertson Guy A. Rouleau Paul Sandor Jeremiah M. Scharf Harvey S. Singer Jan Smit Jae Hoon Sul Dongmei Yu Harald Aschauer Harald Aschauer Csaba Barta

Abstract Tourette syndrome (TS) is a neuropsychiatric disorder of complex genetic architecture involving multiple interacting genes. Here, we sought to elucidate the pathways that underlie neurobiology through genome-wide analysis. We analyzed genotypic data 3581 individuals with TS and 7682 ancestry-matched controls investigated associations sets genes are expressed in particular cell types operate specific neuronal glial functions. employed self-contained, set-based association method...

10.1038/s41398-020-01082-z article EN cc-by Translational Psychiatry 2021-01-18

<h3>Objective</h3> To examine prospectively the association between group A <i>Streptococcus</i> (GAS) pharyngeal exposures and exacerbations of tics in a large multicenter population youth with chronic tic disorders (CTD) across Europe. <h3>Methods</h3> We followed up 715 children CTD (age 10.7 ± 2.8 years, 76.8% boys), recruited by 16 specialist clinics from 9 countries, for months on average. Tic, obsessive-compulsive symptom (OCS), attention-deficit/hyperactivity disorder (ADHD) severity...

10.1212/wnl.0000000000011610 article EN Neurology 2021-03-22

Background . Social and emotional deficits were recently considered as inherent features of individuals with attention-deficit hyperactivity disorder (ADHD), but only sporadic literature data exist on emotion recognition in adolescents ADHD. The aim the present study was to establish profile adolescent boys ADHD comparison control adolescents. Methods Forty-four (13–16 years) participated after informed consent; 22 had a clinical diagnosis ADHD, while also assessed from matched for age Raven...

10.1155/2014/761340 article EN cc-by BioMed Research International 2014-01-01

Psychostimulants are considered first-line pharmacotherapy for youth with attention-deficit/hyperactivity disorder (ADHD), but questions remain regarding the comparative efficacy of amphetamine- and methylphenidate-based agents. Our objective was to describe two acute randomized, double-blind, placebo-controlled, head-to-head studies lisdexamfetamine dimesylate (LDX) osmotic-release oral system methylphenidate (OROS-MPH) in adolescents ADHD. Adolescents (13–17 years) diagnosed ADHD according...

10.1007/s40263-017-0468-2 article EN cc-by-nc CNS Drugs 2017-10-04

Methylphenidate is the most frequently used medication for treatment of attention-deficit/hyperactivity disorder (ADHD) in Europe. Following concerns about its safety, European Commission called research into long-term effects methylphenidate on children and adolescents with ADHD. The Attention Deficit Hyperactivity Disorder Drugs Use Chronic Effects (ADDUCE) programme was designed to address this call. At heart a 2-year longitudinal naturalistic pharmacovigilance study being conducted 27...

10.1136/bmjopen-2015-010433 article EN cc-by-nc BMJ Open 2016-04-01

Attention-deficit/hyperactivity disorder (ADHD) is increasingly recognized as a persistent requiring long-term management. Our objective was to evaluate the 2-year safety and efficacy of lisdexamfetamine dimesylate (LDX) in children adolescents with ADHD. Participants (aged 6–17 years) ADHD received open-label, dose-optimized LDX 30, 50, or 70 mg/day for 104 weeks. Safety monitoring included treatment-emergent adverse events (TEAEs), vital signs, electrocardiography, growth. The TEAEs...

10.1007/s40263-017-0443-y article EN cc-by-nc CNS Drugs 2017-06-30
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