A5100612928- Gastric Cancer Management and Outcomes
- Colorectal Cancer Treatments and Studies
- HER2/EGFR in Cancer Research
- Cancer-related molecular mechanisms research
- Gastrointestinal Tumor Research and Treatment
- Radiopharmaceutical Chemistry and Applications
- Lymphoma Diagnosis and Treatment
- Viral-associated cancers and disorders
- Lung Cancer Research Studies
- Chronic Lymphocytic Leukemia Research
- Salivary Gland Tumors Diagnosis and Treatment
- Cholangiocarcinoma and Gallbladder Cancer Studies
- Helicobacter pylori-related gastroenterology studies
- Neuroendocrine Tumor Research Advances
- Head and Neck Cancer Studies
- Hepatocellular Carcinoma Treatment and Prognosis
- Cancer Immunotherapy and Biomarkers
- PI3K/AKT/mTOR signaling in cancer
- Enhanced Recovery After Surgery
- Glioma Diagnosis and Treatment
- Cell Adhesion Molecules Research
- interferon and immune responses
- Intraperitoneal and Appendiceal Malignancies
- Meningioma and schwannoma management
- Neuroblastoma Research and Treatments
Lishui Central Hospital
2024
Wenzhou Medical University
2024
University of Hong Kong
2022
Fudan University
2013-2022
Huadong Hospital
2022
University of Hong Kong - Shenzhen Hospital
2022
Central South University
2019-2021
Xiangya Hospital Central South University
2019-2021
Peking University Cancer Hospital
2009-2020
Peking University
2009-2020
Purpose To evaluate the efficacy and safety of hepatic arterial infusion (HAI) oxaliplatin 5-fluorouracil for advanced perihilar cholangiocarcinoma (PCC) in this prospective phase II study. Materials Methods The protocol was approved by local ethics committee, all patients gave informed consent. Patients with nonresectable PCC were included a prospective, open study investigating HAI through interventionally implanted port catheters. consisted infusions 40 mg/m2 2 hours, followed 800 22...
Head and neck squamous cell carcinoma (HNSCC) is one of the greatest public challenges because delayed diagnosis poor prognosis. In this study, we established an autophagy-associated long non-coding (Lnc)RNA prognostic signature to assess prognosis HNSCC patients. The LncRNA expression profiles clinical information 499 samples were available in Cancer Genome Atlas. Autophagic LncRNAs analyzed using Pearson correlation. A co-expression network showed interactions between autophagic genes...
4526 Background: Several studies have shown that HER2 is a negative prognostic factor in GC; however, the incidence of this disease has not been reliably established. Reported HER2-positivity rates vary widely (6–35%) due to small sample sizes and methodological differences between studies. The international, Phase III ToGA trial, which evaluating trastuzumab (herceptin) + fluoropyrimidine (5-FU or capecitabine) cisplatin vs chemotherapy alone advanced HER2-positive GC, first prospective...
Neuroendocrine neoplasms (NENs) are relatively rare and heterogeneous malignancies with two major subtypes: low-grade neuroendocrine tumor (NET) high-grade carcinoma (NEC). Comprehensive molecular characterization of NENs is needed to refine our understanding the biological underpinnings different NEN subtypes predict disease progression more accurately.We performed whole-exome sequencing (WES) samples from 49 patients (25 NETs 24 NECs) arising stomach, intestines or lung. Clinicopathologic...
Background Clinical outcome in patients with primary central nervous lymphoma (PCNSL) is variable and poorly predictable. This study investigated the association of clinical features immune markers prognosis PCNSL. Methods One hundred fifteen newly diagnosed PCNSL at institution were considered eligible for this study. characteristics biochemical assay data collected. Immunohistochemical staining Cyclin D3, E, Foxp1, LMO2 performed. All cases followed-up regularly. Results The common sites...
Abstract Introduction: The treatment strategy for low-grade gliomas (LGGs) is still controversial, and there are no standardized criteria to predict the prognosis of patients with LGGs. Magnetic resonance imaging (MRI) a routine test preoperative diagnosis LGG can reflect destructive features tumor. In present study, we aimed explore relationship between MRI in LGG. Methods: Clinical data 80 pathologically proved LGGs January 2010 December 2016 were analyzed retrospectively. classified as...
Abstract Radiation‐induced heart disease (RIHD) is a heterogeneous, delayed, and potentially fatal adverse reaction to radiation that can damage all structures of the heart, including pericardium, myocardium, coronary arteries, valves, conduction system, leading series diseases. Acute chronic processes play role in development RIHD, onset times which range from months decades. However, clinical manifestations RIHD are usually insidious, overlap with several other diseases, lack specificity....
e15090 Background: The objective was to evaluate the effect of preoperative administration TACE and chemotherapy on hepatic injury postoperative outcome in patients with colorectal liver metastases (CRM) Methods: Seventy seven underwent resection for CRM between January 1999 December 2007 were evaluated. Pathologic review non-tumorous performed using established criteria steatosis, steatohepatitis, sinusoidal dilation. two different treatment hepatotoxicity analyzed. Results: 40 (51.9%)...
We conducted this study to evaluate if a reduced cumulative dose of induction and concurrent cisplatin conferred similar favorable outcomes when compared trial NPC-0501. Newly diagnosed nasopharyngeal carcinoma (NPC) with stage III-IVA were prospectively recruited from January 2015 September 2019. Induction chemotherapy (IC) consisted 80mg/m2 on day 1 capecitabine 1000mg/m2 twice daily 14 every 3 weeks for cycles followed by chemoradiotherapy (CCRT) 2 100mg/m2 given weeks. Tumor response was...
e18931 Background: Very few options exist for gastric cancer patients treated with two or more previous chemotherapy regimens. Recent randomized controlled trial ATTRACTION-2 of US Food and Drug Administration-approved anti-PD-1 drug nivolumab demonstrated improved patient outcomes in advanced gastro-oesophageal junction cancer. Methods: To understand the value better, we developed a Markov model to compare cost-effectiveness apatinib third-line treatment by estimating costs (2017 RMB)...