Bo Xia

ORCID: 0000-0002-0628-1910
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About
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Research Areas
  • Radio Frequency Integrated Circuit Design
  • Advancements in PLL and VCO Technologies
  • Bluetooth and Wireless Communication Technologies
  • Epigenetics and DNA Methylation
  • Analog and Mixed-Signal Circuit Design
  • Biotin and Related Studies
  • Microwave Engineering and Waveguides
  • Plant-Microbe Interactions and Immunity
  • Zebrafish Biomedical Research Applications
  • Carcinogens and Genotoxicity Assessment
  • PARP inhibition in cancer therapy
  • DNA Repair Mechanisms
  • Chromium effects and bioremediation
  • Thermal Regulation in Medicine
  • Click Chemistry and Applications
  • Enzyme Production and Characterization
  • Aquatic and Environmental Studies
  • Drug Transport and Resistance Mechanisms
  • Reproductive tract infections research
  • Wireless Networks and Protocols
  • RNA and protein synthesis mechanisms
  • Metabolomics and Mass Spectrometry Studies
  • Plant tissue culture and regeneration
  • Intensive Care Unit Cognitive Disorders
  • Tea Polyphenols and Effects

Hunan Agricultural University
2011-2024

Changsha University of Science and Technology
2011-2024

Hunan Provincial Center for Disease Control and Prevention
2024

Yangtze University
2023-2024

Tianjin University
2003-2023

Bengbu Medical College
2023

Anhui Provincial Hospital
2023

Shenzhen Center for Disease Control and Prevention
2011-2022

Northeast Electric Power University
2022

Sichuan Animal Science Academy
2022

Tumour necrosis factor-α-induced protein 8 (TNFAIP8) has been recently documented in various malignancies, but its role epithelial ovarian cancer (EOC) remains unknown. expression was determined by real-time reverse transcription PCR and western blot analysis. tissues, consisting of serous, mucinous, endometrioid clear cell histotypes, from 202 EOC patients (International Federation Gynecologists Obstetricians I–IV) who underwent primary cytoreduction were collected. Then, we examined the...

10.1038/bjc.2013.501 article EN cc-by-nc-sa British Journal of Cancer 2013-08-27

Studies have shown that prebiotics can affect meat quality; however, the underlying mechanisms remain poorly understood. This study aimed to investigate whether flavor of chicken via gut microbiome and metabolome. The content was collected from chickens fed with or without (galacto-oligosaccharides xylo-oligosaccharides) subjected metabolome analyses, whereas transcriptome sequencing performed using breast. Prebiotic supplementation yielded a slight improvement not statistically significant...

10.1016/j.psj.2022.102122 article EN cc-by-nc-nd Poultry Science 2022-08-30

An automatic RC time constant tuning scheme is proposed for high linearity continuous-time g/sub m/-C and active circuits in a low power consumption environment. Instead of changing the m/ (in filters), tuned by discretely varying integration capacitors to preserve linearity. The auto-tuning circuit, consisting an analog integrator, voltage comparator, digital engine, generates control word sets on-chip obtain time-constant accuracy /spl plusmn/2-10%. verified experimental results test chip...

10.1109/tcsi.2004.836852 article EN IEEE Transactions on Circuits and Systems I Fundamental Theory and Applications 2004-11-01

A fully integrated CMOS low-IF Bluetooth receiver is presented. The consists of a radio frequency (RF) front end, phase-locked loop (PLL), an active complex filter, Gaussian shift keying (GFSK) demodulator, and offset cancellation circuit. highlights the include low-power filter with nonconventional tuning scheme high-performance mixed-mode GFSK demodulator. chip was fabricated on 6.25-mm <sup xmlns:mml="http://www.w3.org/1998/Math/MathML" xmlns:xlink="http://www.w3.org/1999/xlink">2</sup>...

10.1109/jssc.2002.806277 article EN IEEE Journal of Solid-State Circuits 2003-01-01

Human normal cell-based systems are needed for drug discovery and toxicity evaluation. hTERT or viral genes transduced human cells currently widely used these studies, while exhibited abnormal differentiation potential response to biological chemical signals. In this study, we established bronchial epithelial (HNBEC) using a defined primary cell culture medium without transduction of exogenous genes. This system may involve decreased IL-1 signaling enhanced Wnt in cells. Our data...

10.1371/journal.pone.0123520 article EN cc-by PLoS ONE 2015-04-10

Abstract Furanodiene is a natural terpenoid isolated from Rhizoma Curcumae , well-known Chinese medicinal herb that presents anticancer effects in various types of cancer cell lines. In this study, we have successfully established zebrafish xenografts with 5 human lines; and validated these models anti-cancer drugs used clinically for treating patients. We found was therapeutically effective JF 305 pancreatic cells MCF-7 breast xenotranplanted into zebrafish. showed markedly synergistic...

10.1038/s41598-019-40866-2 article EN cc-by Scientific Reports 2019-03-14

Hypsizygus marmoreus (H. marmoreus) spoilage caused by Trichoderma harzianum (T. harzianum) results in significant financial losses, and the natural preservatives are being sought after to replace synthetic preservatives. To determine antifungal activity of cinnamic acid (CA) against T. clarify induced disease resistance mechanism H. harzianum, CA (0.113 mg·mL−1)-protocatechuic (0.121 mg·mL−1)-CaCl2 (0.83%)-NaCl (0.65%)-pullulan (0.35%) composite preservative (CACP) at spray rate 13:1 was...

10.1016/j.lwt.2023.115108 article EN cc-by-nc-nd LWT 2023-07-01

Intensive study of the metabolome during Douchi fermentation can provide new knowledge for optimizing process. In this work, metabolic characterization throughout Mucor racemosus was investigated using gas chromatography with time-of-flight mass spectrometry. A total 511 peaks were found, and 114 metabolites identified. The process clearly distinguished into two main phases by principal components analysis orthogonal partial least squares-discriminant analysis. All samples in score plots...

10.1002/fsn3.1042 article EN cc-by Food Science & Nutrition 2019-04-21

Alzheimer's disease, the leading cause of dementia in elderly, is a complex neurodegenerative disorder which leads to progressive decline cognitive functions.A rapid screening model highly demanded for identification and evaluation novel anti-Alzheimer's disease drugs from large numbers compounds.Until now, numerous studies utilized zebrafish drug discovery.Since aluminum can induce similar biological activity as Alzheimer patients, this study, we developed animal using 3 5 day...

10.17265/2328-2150/2016.04.003 article EN cc-by-nc Journal of Pharmacy and Pharmacology 2016-04-10

This study reports the optimization of culture conditions and medium components M9, an endophytic strain Bacillus amyloliquefaciens, which we had previously isolated from kiwifruit, evaluation its effect on kiwifruit postharvest protection against soft rot. The method one-factor-at-a-time was used to determine optimum conditions, response surface methodology applied optimize constituents. After optimization, a high rate antifungal activity (73.12% decrease in decay rate) by M9 filtrate rot...

10.1111/jfbc.13551 article EN Journal of Food Biochemistry 2020-11-05

An efficient mixed-mode Gaussian frequency-shift keying (GFSK) demodulator with a frequency offset cancellation circuit is presented. The structure suitable for low-IF Bluetooth receiver and can also be applied to other receivers involving continuous phase shift (CPSK) signals. implementation robust tolerate process variations without requiring calibration. It track cancel the time-varying local oscillator between transmitter during entire reception period. chip was fabricated in CMOS...

10.1109/jssc.2003.814424 article EN IEEE Journal of Solid-State Circuits 2003-07-29

Liuyang Douchi is a kind of traditional fermented Aspergillus-type in China for excellent favor. However, studies on the microbial diversity and characterization predominate fungi are few. In present study, Illumina HiSeq sequencing was performed to reveal fluctuation characteristics during fermentation. Results showed that Staphylococcus (33.86%), Staphylococcaceae_unclassified (27.39%) Pediococcus (8.80%) were dominated bacteria, while Petromyces (74.57%), Rhizopus (10.93%) Penicillium...

10.1016/j.lwt.2021.112567 article EN cc-by-nc-nd LWT 2021-10-05

This work presents a configurable time-interleaved pipeline architecture as an efficient solution for the ADC design in high data rate multi-standard radios. The is implemented 0.25-/spl mu/m BiCMOS process part of integrated dual mode 802.11b/Bluetooth direct conversion receiver. Its structure can be configured to accommodate different sampling and dynamic range requirements both standards. techniques employed at system circuit levels optimize power consumption are described. An on-line...

10.1109/jssc.2005.864131 article EN IEEE Journal of Solid-State Circuits 2006-03-01

In this paper, an approach to map the Bluetooth and 802.11b standards specifications into architecture for building blocks of a dual-mode direct conversion receiver is proposed. The design procedure focuses on optimizing performance in each operating mode while attaining efficient dual-standard solution. impact expected nonidealities characteristics block are evaluated through bit-error-rate simulations. proposed verified fully integrated implementation from low-noise amplifier...

10.1109/tcsi.2005.862288 article EN IEEE Transactions on Circuits and Systems I Fundamental Theory and Applications 2006-05-01
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