A5100772462- Ferroptosis and cancer prognosis
- Bladder and Urothelial Cancer Treatments
- Radiomics and Machine Learning in Medical Imaging
- Epigenetics and DNA Methylation
- Cancer, Lipids, and Metabolism
- Parkinson's Disease Mechanisms and Treatments
- Cancer-related molecular mechanisms research
- Cancer Immunotherapy and Biomarkers
- RNA modifications and cancer
- Head and Neck Cancer Studies
- Immune cells in cancer
- Amyotrophic Lateral Sclerosis Research
- Catalytic Processes in Materials Science
- Organ Transplantation Techniques and Outcomes
- Nigella sativa pharmacological applications
- Pancreatic and Hepatic Oncology Research
- Catalysis and Oxidation Reactions
- Urinary and Genital Oncology Studies
- Brain Metastases and Treatment
- Renal cell carcinoma treatment
- MRI in cancer diagnosis
- Inflammatory Bowel Disease
- Autophagy in Disease and Therapy
- Bone Metabolism and Diseases
- Brain Tumor Detection and Classification
First Affiliated Hospital of Xi'an Jiaotong University
2016-2025
Lanzhou University
2020-2024
Lanzhou University Second Hospital
2020-2024
Dongguan People’s Hospital
2020-2024
Southern Medical University
2022-2024
Yangzhou University
2024
Taizhou Second People's Hospital
2024
Jilin University
2024
Xi'an Jiaotong University
2015-2023
Qilu University of Technology
2022
Abstract The prediction of patient disease risk via computed tomography (CT) images and artificial intelligence techniques shows great potential. However, training a robust model typically requires large-scale data support. In practice, the collection medical faces obstacles related to privacy protection. Therefore, present study aims establish federated learning overcome island problem identify high-risk patients with postoperative gastric cancer recurrence in multicentre, cross-institution...
The progression of bladder cancer (BC) from non-muscle-invasive (NMIBC) to muscle-invasive (MIBC) significantly increases disease severity. Although the tumor microenvironment (TME) plays a pivotal role in this process, heterogeneity cells and TME components remains underexplored. We characterized transcriptomes single 11 BC samples, including 4 NMIBC, MIBC, 3 adjacent normal tissues. Bulk RNA-seq data were used validate clinical features characteristic cells, protein levels these further...
Accurate detection is essential for brain metastasis (BM) management, but manual identification laborious. This study developed, validated, and evaluated a BM (BMD) system.Five hundred seventy-three consecutive patients (10 448 lesions) with newly diagnosed BMs 377 without were retrospectively enrolled to develop multi-scale cascaded convolutional network using 3D-enhanced T1-weighted MR images. BMD was validated prospective validation set comprising an internal (46 349 lesions; 44 BMs)...
Bladder cancer is the most common of urinary system and its treatment has scarcely progressed for nearly 30 years. Advances in checkpoint inhibitor research have seemingly provided a new approach treatment. However, there been issues predicting immunotherapeutic biomarkers identifying therapeutic targets. We downloaded gene expression profile clinical data 408 cases bladder from Cancer Genome Atlas (TCGA) portal, abundance ratio immune cells each sample was obtained via "Cell Type...
Background Resistance to anti-tuberculous drugs is a major challenge in the treatment of tuberculosis (TB). We aimed evaluate clinical availability nanopore-based targeted next-generation sequencing (NanoTNGS) for diagnosis drug-resistant (DR-TB). Methods This study enrolled 253 patients with suspected DR-TB from six hospitals. The diagnostic efficacy NanoTNGS detecting Mycobacterium and its susceptibility or resistance first- second-line anti-tuberculosis was assessed by comparing...
Atherosclerosis (AS) is the main cause of cardiovascular and cerebrovascular diseases. Pueraria lobata (Willd.) Ohwi (Fabaceae) has a positive effect on improving these diseases.The P. proliferation inflammation vascular smooth muscle in AS potential mechanism were investigated.By feeding high-fat diet to 8-week-old apolipoprotein E knockout mice, an atherosclerosis model was created. H&E IHC staining used analyse histopathology mice. CCK-8, TUNEL, scratch tests detect cell proliferation,...
Abstract Purpose Some studies have found that the pathological formation of kidney stones is closely related to injury and inflammatory response. Behaviors such as dietary composition, physical activity, obesity smoking can all affect body’s oxidative stress levels. In order evaluate effects various diets lifestyles on antioxidant systems, an balance score was developed. To investigate whether OBS associated with development stones. Methods Data were taken from National Health Nutrition...
Thymoquinone, isolated from the seeds of Nigella sativa, has exhibited antitumor properties in a variety cancer types. However, few studies have investigated effect thymoquinone (TQ) on migration and invasion renal cell carcinoma (RCC). In present study, our results confirmed that TQ significantly inhibited human RCC 769‑P 786‑O lines, as demonstrated by wound healing Transwell assays. Additionally, upregulated expression E‑cadherin downregulated Snail, ZEB1 vimentin at mRNA protein levels...
Rheumatoid arthritis (RA) is a chronic, progressive and systemic autoimmune disease mainly characterized by symmetric multijoint synovitis. Quercetin has anti‑inflammatory, anti‑oxidation immune regulation activities, therefore shows high medicinal value. The present study aimed to observe the effect of quercetin on fibroblast‑like synoviocytes (FLSs) in RA. (RAFLSs) were pretreated with 50 nmol/l for 2 h then stimulated using TNF‑α 24 subsequent experiments. RAFLSs transfected short...
Bladder cancer (BCa), as the most common malignant tumor of urinary system, has received significant attention in research on clinical application artificial intelligence algorithms. Nevertheless, it been observed that certain investigations use data from various medical facilities to train models for BCa, which may pose a privacy risk. Given this concern, protecting patient during machine learning algorithm training is crucial aspect requires substantial attention. One emerging paradigm...
AIM:To investigate the optimal magnetic pressure and provide a theoretical basis for choledochojejunostomy compressive anastomosis (magnamosis).METHODS: Four groups of neodymium-iron-boron magnets with different pressures 0.1, 0.2, 0.3 0.4 MPa were used to complete magnamosis.Twenty-six young mongrel dogs randomly divided into five groups: four 1 group hand-suture anastomosis.Serum bilirubin levels measured in all before wk, 2 3 mo after surgery.Daily abdominal X-ray fluoroscopy was carried...
Osteosarcoma is the most common primary bone tumor in humans, especially childhood. However, genetic etiology for its pathogenesis remains elusive. It known that microRNAs (miRNAs) are involved development of progression. Here we show microRNA-9 (miR-9) a potential oncogene upregulated osteosarcoma cells. Knockdown miR-9 resulted suppressed colony formation and cell proliferation. Further study identified GCIP, Grap2 cyclin D interacting protein, as direct target miR- 9. In addition, GCIP...