A5089837427- Childhood Cancer Survivors' Quality of Life
- Sarcoma Diagnosis and Treatment
- Hematopoietic Stem Cell Transplantation
- Acute Lymphoblastic Leukemia research
- Bone Tumor Diagnosis and Treatments
- Neuroblastoma Research and Treatments
- Testicular diseases and treatments
- Vascular Tumors and Angiosarcomas
- Glioma Diagnosis and Treatment
- Marine animal studies overview
- Acute Myeloid Leukemia Research
- T-cell and B-cell Immunology
- Hearing, Cochlea, Tinnitus, Genetics
- Immunodeficiency and Autoimmune Disorders
- Physiological and biochemical adaptations
- GDF15 and Related Biomarkers
- Cardiac tumors and thrombi
- Hepatocellular Carcinoma Treatment and Prognosis
- DNA Repair Mechanisms
- Lymphatic System and Diseases
- Chromatin Remodeling and Cancer
- Erythrocyte Function and Pathophysiology
- Lymphoma Diagnosis and Treatment
- Soft tissue tumors and treatment
- Family and Disability Support Research
National Yang Ming Chiao Tung University
2015-2024
Taipei Veterans General Hospital
2015-2024
National Taiwan Normal University
2015-2023
National Taipei University
2011-2019
National Yang Ming University Hospital
2018
Bridge University
2015-2016
Aberdeen Royal Infirmary
2016
National Hsinchu University of Education
2016
Mitsubishi Corporation (Japan)
2016
Jacobson Holman (United States)
2015-2016
Abstract Background There is currently conflicting evidence surrounding the effects of obesity on postoperative outcomes. Previous studies have found to be associated with adverse events, but others no association. The aim this study was determine whether increasing body mass index (BMI) an independent risk factor for development major complications. Methods This a multicentre prospective cohort across UK and Republic Ireland. Consecutive patients undergoing elective or emergency...
Primary bone cancer (BC) incidence by age has not been surveyed in Asia. The patterns of nine subtypes primary BCs registered between 2003 and 2010 were analyzed from Taiwan registry data. More specific analyses conducted within groups (Group I: 0–24 years; Group II: 25–59 III: 60–85+ years). A total 1,238 newly diagnosed subjects with an age-standardized rate (ASR) 6.70 per million person-years. Overall, osteosarcoma (OS: 45 %) was the most common, followed chondrosarcoma (CS: 18 %), Ewing...
Atopic dermatitis (AD) is one of the common allergic diseases in children. The presence was found to have association with risk developing attention-deficit hyperactivity disorder (ADHD) or autistic spectrum (ASD) children, but it still inconclusive. This study investigate longitudinal relationship between AD developed during toddlerhood and subsequent development ADHD ASD later childhood. Toddlers born 1998 2008 diagnosed at age younger than 3 years older 1 month were retrieved from...
Gastric cancer is a common worldwide, particularly in East Asia. Chemotherapy used adjuvant or palliative therapies for gastric cancer. However, subsequent chemoresistance often develops. Growth differentiation factor 15 (GDF15) links to several cancers, but its effect on remains unclear. Here, we analyzed clinical samples from genetic databases and included patients with We dissected the regulatory mechanism underlying GDF15-mediated resistance of cisplatin human cells. showed that GDF15...
To determine whether T cell engraftment and recovery of B immunity could be improved, we prospectively treated 15 children with severe combined immunodeficiency disease (SCID) megadoses haplocompatible CD34+ cells a fixed number CD3+ without previous myeloablative chemotherapy. Evidence was seen in 73% patients (95% confidence interval [CI] = 48%-90%). Engraftment more likely X-linked SCID those evidence maternal at the time diagnosis. In engraftment, median to development CD4 count > 200...
BACKGROUND Currently, little information is available on childhood cancer incidence rates in Eastern Asia. The objective of this study was to report the first population‐based surveillance children and adolescents Taiwan. METHODS Data from Taiwan Cancer Registry were examined for frequencies among individuals ages birth 19 years 1995 2009. Types cancers grouped according International Classification Childhood Cancer. Rates compared by sex age. For further comparisons with other countries,...
The aim of this study was to compare survival before and after 2004 define the prognostic factors for high-grade osteosarcomas beyond those typical young patients with localized extremity disease. Few studies have reported long-term treatment outcomes osteosarcoma in Taiwan. A total 202 primary who received chemotherapy at Taipei Veterans General Hospital between January 1995 December 2011 were retrospectively evaluated compared by period (1995–2003 vs 2004–2011). Patients all ages tumor...
We report the case of a 4-year-old boy with acute lymphoblastic leukemia in high-risk group who suffered from generalized tonic-colonic seizure evolving into status epilepticus, and subsequent left hemiparesis during his first reinduction chemotherapy, consisting dexamethasone, vincristine, l-asparaginase, epirubicin. Superior sagittal sinus cerebral venous thrombosis, predominantly right side, were proved by brain magnetic resonance imaging. After aggressive treatment low-molecular weight...
BackgroundDue to the increase of breastfeeding in infants, iron deficiency anemia (IDA) related prolonged, predominant should be concern. Mostly, manifestation IDA is indistinguishable and enthusiastic advocacy without concomitant education complementary food may lead ignorance breast milk-related IDA, which result impaired psychomotor development baby. This retrospective study was conducted re-emphasize this easily ignored but still prevalent illness.MethodsThis involved 15 babies who were...
Osteosarcoma (OS) patients who suffer manipulation therapy (MT) prior to diagnosis resulted in poor prognosis with increasing metastasis or recurrence rate. The aim of the study is establish an vivo model identify effects MT on OS. enrolled 235 OS were followed up this study. In nude mice tibia injection GFP-labeled human cells randomly allocated into MT(+) that repeated massage tumor site twice a week and no treatment as MT(−) group. five-year survival, rates recorded clinical subjects....
Background Discontinuation of E. coli l ‐asparaginase in patients with acute lymphoblastic leukemia (ALL) is unavoidable upon severe allergic reaction. We sought to examine outcomes following discontinuation due reactions. Procedure evaluated the outcome children enrolled Taiwan Pediatric Oncology Group‐2002‐ALL protocol between 2002 and 2012, who had discontinued reactions, compared those continued Erwinia (Erwinase) did not. Results Among 700 this study, 33 treatment Five‐year overall...
The incidence of hepatoblastoma is not well known in Taiwan. goal this study was to investigate the rates by age and sex.The data patients with diagnosed from 1995 2012 were obtained population-based Taiwan Cancer Registry. Incidence according sex analyzed. This employed published methods International Agency for Research on calculate age-standardized (ASIRs), standard errors, 95% confidence intervals (CIs), standardized rate ratios (SIRRs).In total, 211 during 18-year period. ASIR 0.76 per...
Background Reinduction therapy has improved the outcomes in children with acute lymphoblastic leukemia (ALL). We sought to determine optimal course(s) of reinduction for standard-risk (SR, or "low-risk" other groups) patients. Also, we evaluated using triple intrathecal without cranial radiation (CrRT) central nervous system (CNS) preventive therapy. Procedure From 2002 2012, all newly diagnosed ALL Taiwan were enrolled Pediatric Oncology Group ALL-2002 protocol. SR patients randomized...