A5077527200- Pluripotent Stem Cells Research
- Protein Hydrolysis and Bioactive Peptides
- Schizophrenia research and treatment
- Enzyme Production and Characterization
- Tissue Engineering and Regenerative Medicine
- Healthcare Decision-Making and Restraints
- Peptidase Inhibition and Analysis
- Soybean genetics and cultivation
- Energy Efficient Wireless Sensor Networks
- CRISPR and Genetic Engineering
- 3D Printing in Biomedical Research
- Context-Aware Activity Recognition Systems
- Indoor and Outdoor Localization Technologies
- Neuroblastoma Research and Treatments
- Neuroendocrine Tumor Research Advances
- Lung Cancer Research Studies
- Cell death mechanisms and regulation
- Injection Molding Process and Properties
- Phytase and its Applications
- Child Nutrition and Feeding Issues
- Circular RNAs in diseases
- Healthcare professionals’ stress and burnout
- Advanced Materials Characterization Techniques
- Iterative Learning Control Systems
- Studies on Chitinases and Chitosanases
Offenburg University of Applied Sciences
2022-2025
Karlsruhe Institute of Technology
2025
The University of Agriculture, Peshawar
2023-2025
The Ohio State University
2024
Lahore General Hospital
2024
Baqai Medical University
2024
The University of Melbourne
2023
Orygen
2023
Vilnius University
2023
NED University of Engineering and Technology
2021
Protein hydrolysis under acidic conditions can improve the product quality, nutrient availability, and cost efficiency, particularly when neutral or alkaline enzymes are ineffective. Six fungal aspartic endopeptidases (FAPs) were recombinantly expressed as active in
Enhancing floret persistence and bloom duration in ornamental plants through foliar-applied calcium promotes sustainability by improving nutrient efficiency, reducing environmental impacts, conserving resources, boosting commercial value. This two-year study (2021–2022) evaluated the effects of foliar application on gladiolus (cv. White Prosperity). The experiment followed a Randomized Complete Block Design with split-plot arrangement, replicated three times. Main plots received different...
A churn prediction system guides telecom service providers to reduce revenue loss. However, the development of a for industry is challenging task, mainly due large size data, high dimensional features, and imbalanced distribution data. In this paper, we present solution inherent problems prediction, using concept Transfer Learning (TL) Ensemble-based Meta-Classification. The proposed method TL-DeepE applied in two stages. first stage employs TL by fine-tuning multiple pre-trained Deep...
To harmonize two ascertainment and severity rating instruments commonly used for the clinical high risk syndrome psychosis (CHR-P): Structured Interview Psychosis-risk Syndromes (SIPS) Comprehensive Assessment of At-Risk Mental States (CAARMS).
Abstract A novel peptidyl-lys metalloendopeptidase ( Tc -LysN) from Tramates coccinea was recombinantly expressed in Komagataella phaffii using the native pro-protein sequence. The peptidase secreted into culture broth as zymogen (~38 kDa) and mature enzyme (~19.8 simultaneously. -LysN purified to homogeneity with a single step anion-exchange chromatography at pH 7.2. N-terminal sequencing TMTpro Zero mass spectrometry of Tc- LysN indicated that pro-peptide cleaved between amino acid...
Diabetic Cardiomyopathy (DCM) is characterized by myocardial dysfunction caused diabetes mellitus. After-effects of diabetic cardiomyopathy are far more lethal than non-diabetic cardiomyopathy. More 300 million people suffer from and cardiovascular disorder which expected to be elevated an alarming figure 450 2030. Recent studies suggested that miRNA plays important role in the onset This study was designed identify responsible for using silico vitro approaches. In this study,...
A unique kind of pluripotent cell, i.e., Induced stem cells (iPSCs), now being targeted for iPSC synthesis, are produced by reprogramming animal and human differentiated (with no change in genetic makeup the sake high efficacy iPSCs formation). The conversion specific to has revolutionized cell research making more controllable regenerative therapy. For past 15 years, somatic pluripotency with force expression specified factors been a fascinating field biomedical study. that technological...
Abstract Background Human induced pluripotent stem cells (hiPSCs) and their differentiated cell types have a great potential for tissue repair regeneration. While the primary focus of using hiPSCs has historically been to regenerate damaged tissue, emerging studies shown more potent effect hiPSC-derived paracrine factors on However, precise contents transplanted secretome are ambiguous. This is mainly due lack tools distinguish cell-specific from host-derived proteins in complex...
Abstract The natural polymer chitin is an abundant source for valuable N-acetylchitooligosaccharides and N-acetylglucosamine applicable in several industries. endochitinase Chit36-TA from Trichoderma asperellum was recombinantly expressed Komagataella phaffii the enzymatic degradation of unused insect exuviae into N-acetylchitooligosaccharides. purified by Ni–NTA affinity chromatography subsequently biochemically characterized. After deglycosylation, had a molecular weight 36 kDa. optimum pH...
Various neutral and alkaline peptidases are commercially available for use in protein hydrolysis under to conditions. However, the of proteins acidic conditions by applying fungal aspartic (FAPs) has not been investigated depth so far. The aim this study, thus, was purify a FAP from commercial enzyme preparation, ROHALASE® BXL, determine its biochemical characteristics, investigate application food animal feed conditions.A Trichoderma reesei derived FAP, with an apparent molecular mass 45.8...
Targeting drug delivery has been a focus of researchers in recent years for cancer and other diseases. Many approaches such as liposomes, exosomes, nanoparticles (magnetic), encapsulation etc. have developed investigated their clinical applications. But disadvantages linked to these therapies limit them be used settings. Cell based systems emerged an alternative therapies. Among cell types, mesenchymal stem cells (MSCs) proved potential type research due its many characteristics including...
Location systems are core technologies for enabling pervasive computing smart spaces. Signal strength based location estimation offers economical viability and sufficient accuracy numerous services. Despite extensive research being carried out in this positioning method, tedious lengthy development life cycle prohibits wide scale deployment of these systems. We present a new approach on online machine learning paradigm which significantly reduces the time. Besides rapid shows competitive...
Objective: To look at patients with -thalassemia's skeletal patterns. Study Design: Cross sectional, Observational. Setting: Karachi Medical and Dental College, Baqai College University, Husaini Institute of Heamatological Studies Fatmid Foundation. Period: 2012 to 2020. Methods: Fifty major thalassemia were voluntarily chosen random, 50 lateral cephalometric X-rays taken using the Steiner Analysis inclusion criteria Thalassemia Patient under 35 without any systemic disorders. exclusion...
<title>Abstract</title> <bold>Background:</bold> Self-medication is a global health concern, particularly the use of analgesics without medical consultation. This practice prevalent among students due to their knowledge pharmacology, easy access medications, and belief that mild issues do not require attention.<bold>Methods:</bold> A cross-sectional study was conducted in Punjab. Using RAOSOFT sample calculator, minimum size 397 determined. Data from 464 participants were collected through...
Background: Human induced pluripotent stem cells (hiPSCs) and their derived cardiomyocytes (hiPSC-CMs) have been used for cell-based therapies myocardial regeneration. Underlying paracrine signals from these hiPSC-CMs shown to play a critical role in improving the function of ischemic myocardium. However, characterization transplanted cell proteome vivo has challenging due lack tools distinguish cell-specific complex multicellular microenvironment. Methods: To establish labelling, we adopted...
Soybean is a vital crop for food and oil production, yet its yield quality are often compromised by suboptimal nutrient management. This study aimed to address this issue investigating the effects of sulfur time application on soybean at Research Farm The University Agriculture Peshawar during Kharif season 2022. experiment followed randomized complete block design with three replicates. It evaluate four levels (0, 20, 40, 60 kg ha-1) applied different growth stages (S1=sowing,...