A5017208008- Cancer-related cognitive impairment studies
- Cancer survivorship and care
- Ferroptosis and cancer prognosis
- Cancer Immunotherapy and Biomarkers
- Family Support in Illness
- RNA modifications and cancer
- Heart Rate Variability and Autonomic Control
- Tryptophan and brain disorders
- Glioma Diagnosis and Treatment
- Bioinformatics and Genomic Networks
- Inflammatory Biomarkers in Disease Prognosis
- 14-3-3 protein interactions
- Cutaneous Melanoma Detection and Management
- Polyamine Metabolism and Applications
- Lung Cancer Research Studies
- GDF15 and Related Biomarkers
- Colorectal Cancer Treatments and Studies
- Esophageal Cancer Research and Treatment
- Histone Deacetylase Inhibitors Research
- Cancer, Hypoxia, and Metabolism
- COVID-19 and Mental Health
- Vagus Nerve Stimulation Research
- Genetic factors in colorectal cancer
- Intensive Care Unit Cognitive Disorders
- Melanoma and MAPK Pathways
Southern Medical University Shenzhen Hospital
2022-2025
Third Affiliated Hospital of Southern Medical University
2024-2025
Anhui Medical University
2013-2025
Second Hospital of Anhui Medical University
2013-2025
Shanghai Tenth People's Hospital
2020
Abstract Background Patients with major depressive disorder (MDD) have an increased risk of breast cancer (BC), implying that these two diseases share similar pathological mechanisms. This study aimed to identify the key pathogenic genes lead occurrence both triple-negative (TNBC) and MDD. Methods Public datasets GSE65194 GSE98793 were analyzed differentially expressed (DEGs) shared by datasets. A protein-protein interaction (PPI) network was constructed using STRING Cytoscape PPI cytoHubba....
Laryngeal squamous cell carcinoma (LSCC) is a prevalent head and neck neoplasm with escalating global morbidity mortality rates. Despite the increasing burden of LSCC, drugs currently approved for its treatment are limited. Therefore, it necessary to identify novel promising that target LSCC. Cucurbitacin E (CuE) naturally oxygenated tetracyclic triterpenoid suppresses several cancers. However, anti-LSCC activity molecular mechanisms action remain unclear. This study explored impact on...
Objectives To evaluate the effects of CALM intervention on cancer-related fatigue (CRF), quality life (QOL), and heart rate variability (HRV) in non-small cell lung cancer (NSCLC) patients.
Objective Our study examines how non-small cell lung cancer (NSCLC) survivors undergoing immunotherapy can experience reduced anxiety and psychological distress, improved quality of life (QOL) increased efficacy. Methods 133 men 20 women with NSCLCs were enrolled. In a randomised controlled trial involving care as usual group (CG) music therapy (MTG), the researchers employed various tools such Self-Rating Anxiety Scale, Symptom Distress Thermometer, Functional Assessment Cancer...
Background: CD4+ memory T cells (CD4+ MTCs), as an important part of the microenvironment affecting tumorigenesis and progression, have rarely been systematically analyzed. Our purpose was to comprehensively analyze effect MTC infiltration on prognosis colon adenocarcinoma (COAD). Methods: Based RNA-Seq data, weighted gene co-expression network analysis (WGCNA) used screen genes most associated with cancer then identify hub construct a prognostic model using least absolute shrinkage...
Abstract Purpose This study aims to evaluate the effects of managing cancer and living meaningfully (CALM) intervention on neutrophil-to-lymphocyte ratio (NLR), fear recurrence, quality life general distress in lung patients explore whether there is a correlation between NLR, life. Methods Eighty with clinical range scores (≥13 points) FCRI severity subscale were recruited randomly assigned CALM group or usual care (UC). The NLR was recorded before after treatment. Fear Cancer Recurrence...
Abstract Background Breast cancer is a malignant disease that seriously affects women's health,there certain connection between depression and it, however, the mechanism of their interrelationship still unclear.This article aims to explore common genetic characteristics potential molecular mechanisms breast through multiple data sets. Methods Download related datasets from TCGA database NCBI GEO public database, use R package "Limma" analyze difference data, identify differentially expressed...
Abstract PurposeWe sought to perform survival analysis of patients with thoracic esophageal squamous cell carcinoma (ESCC) receiving definitive radiotherapy and identify prognostic factors among hematological dosimetric factors. Methods Cases ESCC treated chemoradiation between 2014 2017 were identified. The impact clinicopathological factors’ on overall (OS) was analyzed via Cox proportional hazards model. Absolute lymphocyte counts (ALC) the neutrophil-to-lymphocyte ratio (NLR = ANC/ALC)...
Abstract Background: Anterior findings denoted that catechol-O-methyltransferase (COMT) have been considered as genetic risk for chemo-brain. However, the mediation of COMT polymorphism chemo-brain in breast cancer patients with various index ki-67 was still unknown. Objective : The current research intended to assess by genotype ki-67. Methods: Breast (65 ki-67<14%, 75 ki-67>14%) fulfilled cognitive tests pre and post adjuvant chemotherapy, three single-nucleotide polymorphisms (SNPs)...
Abstract Purpose The purpose of this study was investigating the correlation between cytokine levels and chemotherapy-induced cognitive impairment in non-Hodgkin’s lymphoma (NHL) patients. Methods A total 30 patients with NHL were included study. These completed assessment which including IL-4 IL-6 before chemotherapy after 2 courses chemotherapy. Results subjects' higher treatment than (t = 2.85, P < 0.01) lower (Z= -3.17, 0.01). has a weak RM PM (r 0.282 0.270, respectively, all 0.05)....