- Advancements in Battery Materials
- Extracellular vesicles in disease
- Supercapacitor Materials and Fabrication
- MicroRNA in disease regulation
- Cancer, Lipids, and Metabolism
- Circular RNAs in diseases
- RNA modifications and cancer
- Gastric Cancer Management and Outcomes
- Semiconductor materials and devices
- Pulmonary Hypertension Research and Treatments
- Liver Disease Diagnosis and Treatment
- Metabolism, Diabetes, and Cancer
- Cancer-related molecular mechanisms research
- Ga2O3 and related materials
- Advanced Battery Materials and Technologies
- Venous Thromboembolism Diagnosis and Management
- MXene and MAX Phase Materials
- Nanoplatforms for cancer theranostics
- Pancreatic and Hepatic Oncology Research
- Water-Energy-Food Nexus Studies
- Anaerobic Digestion and Biogas Production
- Microbial bioremediation and biosurfactants
- Plant-based Medicinal Research
- Plant responses to elevated CO2
- Extraction and Separation Processes
Wuhan Polytechnic University
2025
Fujian Agriculture and Forestry University
2025
Imperial College London
2025
National Clinical Research Center for Digestive Diseases
2022-2024
Capital Medical University
2021-2024
Beijing Friendship Hospital
2021-2024
Anhui University of Science and Technology
2024
Anhui Science and Technology University
2024
University of Science and Technology Beijing
2023
Beijing Chao-Yang Hospital
2022-2023
Doxorubicin (DOX) is a widely used first-line antitumor agent; however, acquired drug resistance and side effects have become the main challenges to effective cancer therapy. Herein, DOX loaded into iron-rich metal-organic framework/tannic acid (TA) nanocomplex form tumor-targeting acid-activatable delivery system (MOF/TA-DOX, MTD). Under acidic tumor microenvironment, MTD simultaneously releases ferrous ion (Fe2+) accompanied by degradation. Apart from chemotherapeutic effect, elevates...
Fast reaction kinetics and excellent performance were achieved in 2D laminate Li<sub>3</sub>VO<sub>4</sub>/C prepared <italic>via</italic> a scalable economical biomass-aided approach.
In this study, C. pyrenoidosa were cultured with seven different concentrations of Na2SeO4 (0–10 mg/L), and the effects on growth, Se-forms, nutritional quality explored. The results showed that at concentration 0.5 mg/L Na2SeO4, plump healthy; contents biomass, soluble protein, lipids, TPUFA reached highest level; total Se content in increased increasing concentrations. However, proportion organic pyrenoidosa. value 87.58% Na2SeO4. Among forms, SeMet accounted for largest proportion, while...
The chromatin regulator MLL2 (KMT2B) is the primary histone 3 lysine 4 (H3K4) trimethyltransferase acting at bivalent promoters in embryonic stem cells (ESCs) and required for differentiation toward neuroectoderm. Here, we demonstrate that this requirement occurs during exit from naive pluripotency, days before neuroectoderm impaired. During exit, effect of on transcription subtle, increasing expression a few important neuroectodermal factors. In contrast, MLL2's architecture substantial,...
C@LVO nanoflakes with tailored crystallographic planes of LVO were reversely designed and prepared for the first time via a water-etching strategy, showing outstanding high-rate long-life performance outperforming most LVO-based electrodes.
The most common type of kidney tumor, clear-cell renal cell carcinoma (ccRCC) with relatively insidious development and easily metastatic characteristics is generally insensitive to cytotoxic chemotherapy. abundant polyunsaturated fatty acids (PUFAs) content in advanced ccRCC allows it be intrinsically vulnerable ferroptosis-based therapeutic strategies. Nevertheless, the strategy cause "iron overload" by administration iron-based nanomaterials has limited efficacy. And classic ferroptosis...
Water is one of the most important elements affecting growth ornamental plants. To investigate effects drought stress on growth, values, and physiological properties Begonia semperflorens, watering treatments with 250 mL (control check, CK), 200 (extremely light drought, ELD), 150 (light LD), 100 (moderate MD), 50 (severe SD), 25 severe ESD) B. semperflorens variety “Chao Ao” were performed in this study. As a result, compared to control (CK), number flowers, leaves, branches, leaf size,...
Abstract Gastric cancer (GC) ranks third among cancers in terms of mortality rate worldwide. A clear understanding the mechanisms underlying genesis and progression GC will contribute to clinical decision making. N 6 -methyladenosine (m A) is most abundant diverse mRNA modification types regulates multiple facets RNA metabolism. In recent years, emerging studies have shown that m modifications are involved gastric carcinoma tumorigenesis can potentially be valuable new prospects for...
Abstract Osteoarthritis (OA), which is principally featured by progressive joint metabolic imbalance and subsequent degeneration of articular cartilage, a common chronic disease. Arctigenin (ATG), dietary phyto‐oestrogen, has been described to have potent anti‐inflammatory effects. Nevertheless, its protective effects on OA not clearly established. The target our following study evaluate the ATG IL‐1β–induced human chondrocytes mouse model. Our results revealed that pre‐treatment effectively...
Colorectal neoplasms (CRN) include colorectal cancer (CRC) and adenoma (CRA). The relationship between CRN triglyceride-glucose (TyG) index or atherogenic of plasma (AIP) is unclear. This study aims to investigate the roles TyG AIP in predicting people without cardiovascular disease (CVD). 2409 patients CVD underwent colonoscopy were enrolled. Clinical information relevant laboratory test results these collected recorded. According endoscopic pathological results, all participants divided...
Anthocyanins, recognized as stress indicators, particularly under high-light conditions, play a pivotal role in plant responses. The advent of transcriptomics has opened avenues to elucidate the mechanisms underlying high light-induced anthocyanin biosynthesis. This study delved into transcriptomic changes Begonia semperflorens leaves varying light intensities: 950–9600 lx (TL_100), 6800–7000 (HS_75), and 4300–4500 (LS_25). To confirm expression profiles key genes, we chose 12 critical genes...
<title>Abstract</title> Gastric cancer (GC) relies heavily on the reprogramming of lipid metabolism for energy, growth, and survival. Apolipoprotein C-I (APOC1) is implicated in metabolic processes GC, yet precise molecular mechanisms underlying this association remain incompletely understood. In study, we identified APOC1 as a key player GC progression. Our findings show that upregulated tissues cells compared with controls correlated poor prognosis. Furthermore, overexpression promoted...