- Mosquito-borne diseases and control
- Viral Infections and Vectors
- Malaria Research and Control
- Salmonella and Campylobacter epidemiology
- COVID-19 epidemiological studies
- Global Maternal and Child Health
- Streptococcal Infections and Treatments
- Viral gastroenteritis research and epidemiology
- Vibrio bacteria research studies
- Hepatitis Viruses Studies and Epidemiology
- Infective Endocarditis Diagnosis and Management
- Neonatal and Maternal Infections
- Otolaryngology and Infectious Diseases
- Vaccine Coverage and Hesitancy
- Leptospirosis research and findings
- Zoonotic diseases and public health
- Viral Infections and Outbreaks Research
- Cancer and Skin Lesions
- Plant Pathogenic Bacteria Studies
- Spine and Intervertebral Disc Pathology
- Data-Driven Disease Surveillance
- Economic and Environmental Valuation
- Fecal contamination and water quality
- SARS-CoV-2 and COVID-19 Research
- Technology and Data Analysis
International Vaccine Institute
2016-2025
University of Oxford
2017-2022
Sangmyung University
2016
Cheju Halla University
2010
Catholic University of Korea
2005
The rise in dengue fever cases and the absence of vaccines will likely cause governments to consider various types effective means for controlling disease. Given strong public interests potential vaccines, it is essential understand private economic benefits accelerated introduction into sector program markets high-risk countries.A contingent valuation study a hypothetical vaccine was administered 400 households multi-country setting: Vietnam, Thailand, Colombia. All respondents received...
While the global burden of typhoid fever has been often brought up for attention, detailed surveillance information only available limited number countries. As more efficacious vaccines will be in near future, it is essential to understand geographically diverse patterns risk levels and prioritize right populations vaccination effectively control disease. A composite index called factor (TRF) was created based on data with Global Positioning System (GPS). Demographic Health Surveys (DHS)...
Dengue fever is a major public health concern in many parts of the tropics and subtropics. The first dengue vaccine has already been licensed six countries. Given growing interests effective use vaccine, it critical to understand economic burden guide decision-makers setting policy priorities.A standardized cost-of-illness study was conducted three endemic countries: Vietnam, Thailand, Colombia. In order capture all costs during entire period illness, patients were tested with rapid...
Considering the lack of existing evidence on economic burden for diseases caused by group A Streptococcus, we estimated per episode selected diseases. Each cost component direct medical costs (DMCs), non-medical (DNMCs), and indirect (ICs) was separately extrapolated aggregated to estimate income as classified World Bank. Adjustment factors DMC DNMC were generated overcome related data insufficiencies. To address uncertainty surrounding input parameters, a probabilistic multivariate...
Dengue has been prevalent in Colombia with high risk of outbreaks various locations. While the prediction dengue epidemics will bring significant benefits to society, accurate forecasts have a challenge. Given competing health demands Colombia, it is critical consider effective use limited healthcare resources by identifying areas for fever.The Climate Risk Factor (CRF) index was constructed based upon temperature, precipitation, and humidity. Considering conditions necessary vector survival...
Background In Africa, the magnitude of dengue virus (DENV) transmission is largely unknown. Burkina Faso, several outbreaks have been reported and data are often based on findings from outbreak investigations. Methods To better understand epidemiology clinical characteristics in a fever surveillance study was conducted among patients aged 1–55 years, who presented with non-malarial febrile illness at five primary healthcare facilities Ouagadougou, Faso December 2014 to February 2017,...
Introduction Dengue is an important and well-documented public health problem in the Asia-Pacific Latin American regions. However, Africa, information on disease burden limited to case reports of sporadic outbreaks, thus hindering implementation actions for control. To gather evidence undocumented dengue epidemiological studies with standardised methods were launched three locations Africa. Methods analysis In 2014–2017, Vaccine Initiative initiated field at sites Ouagadougou, Burkina Faso;...
The beneficial effects of a strength exercise program and combined training plus walking were examined in overweight with chronic back pain patients. participants randomly placed the group (SEG, n=15), (CEG, control (CG, n=6). All subjects performed twice per week, 50 min session professional instructors for 12 weeks. In order to evaluate intervention effects, lumbar function was measured by flexibility. Roland-Morris disability questionnaire (RMDQ) visual analogue scale (VAS) used level....
Leptospirosis, a prevalent zoonotic disease with One Health priority and of poverty, lacks global economic burden estimates. This study aims to determine the global, regional, country-level cost leptospirosis due loss productivity.The productivity (referred as hereafter) was estimated by converting disability-adjusted life years (DALYs) lost monetary value using per capita gross domestic product (GDP). The country-specific DALYs were obtained from published previously. Non-health GDP (GDP-...
The competitiveness of construction firms may be achieved by effective decision-making and high productivity. Therefore, it is necessary to analyze the efficiency productivity firms. This study aims compare Chinese, Japanese Korea between 2005 2011 using Data Envelopment Analysis (DEA) DEA-based Malmquist methods. analysis process as follows: 1) Decision Making Units, input output variables are selected. 2) Efficiency Korean analyzed applying DEA selected variables. 3) Productivity presented...
Dengue is a major public health problem in the tropics and sub-tropics, but disease less known to non-dengue-endemic countries including Northeast Asia. However, an unexpected dengue outbreak occurred 2014 Japan. Given that autochthonous (domestic) cases had not been reported for past 70 years Japan, this was highly unusual suggests several environmental factors might have changed way favors vector mosquitoes Asian region. A Climate Risk Factor (CRF) index, as validated previous work,...
Dengue fever is a rapidly growing public health problem in many parts of the tropics and sub-tropics world. While there are existing studies on economic burden dengue some dengue-endemic countries, cost components often not standardized, making cross-country comparisons challenging. Furthermore, no such have been available Africa.A patient-specific survey questionnaire was developed applied Burkina Faso, Kenya, Cambodia standardized format. Multiple interviews were carried out order to...
Group A Streptococcus causes a wide range of diseases from relatively mild infections including pharyngitis to more severe illnesses such as invasive and rheumatic heart disease (RHD). Our aim is estimate the cost-effectiveness hypothetical Strep vaccine on multiple manifestations at global-level. Cost-effectiveness analyses were carried out by building potential epidemiological impact vaccines that align with WHO's Preferred Product Characteristics for vaccines. Maximum vaccination costs...
Abstract The spectrum of diseases caused by Streptococcus pyogenes (Strep A) ranges from superficial to serious life-threatening invasive infections. We conducted a scoping review published articles between 1980 and 2021 synthesize evidence state transitions across the Strep A disease spectrum. identified 175 reporting 262 distinct observations transitions. Among included articles, transition an or toxin-mediated another (i.e., recurrent ARF, RHD death) was described 115 times (43.9% all...
ObjectivesInformation on dengue in Africa is limited. To estimate the proportion of dengue-positive cases among febrile patients and describe clinical indicators dengue, we conducted passive health facility-based fever surveillance Mombasa, Kenya.MethodsNon-malarial between one 55 years were enrolled at three facilities March 2016 May 2017. Acute convalescent blood samples collected with an interval 10–21 days. tested RDT a selected subset RT-PCR, acute/convalescent IgM/IgG...
To determine the seroprevalence and transmission dynamics of dengue virus (DENV), age-stratified longitudinal serological surveys were conducted in Bangphae district, Ratchaburi province, Thailand, for 3 years between April 2012 2015.The enrolled healthy children adults 1 55 years-of-age, a serosurvey six repeated bleeds same cohort individuals was every 8 months first 2 (M0, M8, M16) half year (M24, M30, M36) rest study period. All samples tested using in-house indirect sandwich IgG ELISA...
Abstract Background Leptospirosis, a prevalent zoonotic disease with One Health priority and of poverty, lacks global economic burden estimates. This study aims to determine the global, regional, country-level cost leptospirosis due loss productivity. Methodology/Principal Findings The productivity (referred as hereafter) was estimated by converting disability-adjusted life years (DALYs) lost monetary value using per capita gross domestic product (GDP). country-specific DALYs were obtained...
Ticks transmit a wide range of pathogens. The spread tick-borne infections is an emerging, yet often overlooked, threat in the context climate change. have rapidly increased over past few years South Korea despite no significant changes socioeconomic circumstances. We investigated impact change on surge and identified potential disease hot spots at resolution 5 km by km. A composite index was constructed based multiple environmental indicators compared with observed infections. episodes...
We have experienced three cases of extramammary Paget's disease (EMPD) the vulva that received radiation therapy (RT). Here, we analyze efficacy RT and include a literature survey.Three patients with EMPD were treated curative between 1993 1998. One had associated underlying adenocarcinoma vulva. The total doses administered 54~78 Gy/6~8 weeks. Radiation fields encompassed 2 to 3 cm outer margins free from all visible including or not inguinal area using 9 MeV electron 6 MV photon beam....
Background Dengue is a major public health problem in Thailand, but data are often focused on certain dengue-endemic areas. Methods: To better understand dengue epidemiology and clinical characteristics fever surveillance study was conducted among patients aged 1–55 years, who presented with non-localized febrile illness at Bang Phae Community Hospital Ratchaburi province, Thailand from October 2011 to September 2016. Results Among 951 episodes, 130 were dengue-confirmed. Individuals 10–14...
Abstract Antimicrobial resistance (AMR) poses an immediate danger to global health. If unaddressed, the current upsurge in AMR threatens reverse achievements reducing infectious disease–associated mortality and morbidity associated with antimicrobial treatment. Consequently, there is urgent need for strategies prevent or slow progress of AMR. Vaccines potentially contribute both directly indirectly combating Modeling studies have indicated significant gains from vaccination burdens specific...