A5015435327- Electrowetting and Microfluidic Technologies
- Diet and metabolism studies
- Radio Frequency Integrated Circuit Design
- Advancements in PLL and VCO Technologies
- Interactive and Immersive Displays
- Dietary Effects on Health
- Pneumonia and Respiratory Infections
- Immune Response and Inflammation
- Bacterial Infections and Vaccines
- Epilepsy research and treatment
- Energy Harvesting in Wireless Networks
- Cytomegalovirus and herpesvirus research
- Advanced Sensor and Energy Harvesting Materials
- Transition Metal Oxide Nanomaterials
- Modular Robots and Swarm Intelligence
- Pediatric health and respiratory diseases
- Semiconductor Lasers and Optical Devices
- Vibrio bacteria research studies
- Viral Infections and Immunology Research
- Neurogenesis and neuroplasticity mechanisms
- RFID technology advancements
- Pharmacology and Obesity Treatment
- Infectious Encephalopathies and Encephalitis
- Multiple Sclerosis Research Studies
- Zebrafish Biomedical Research Applications
Jiangsu University
2025
Yunnan Agricultural University
2023-2025
Shanghai Medical Information Center
2024
Children's Hospital of Zhejiang University
2013-2022
University of Science and Technology of China
2020
KTH Royal Institute of Technology
2011-2017
Zhejiang University
2015
Tianjin University
2013
Sun Yat-sen University
2013
Sun Yat-sen University Cancer Center
2013
OBJECTIVE We aimed to examine the effects of a 5:2 diet (2 days per week energy restriction by formula diet) or an exercise high-intensity interval training and resistance training) intervention compared with routine lifestyle education (control) on glycemic control cardiometabolic health among adults overweight/obesity type 2 diabetes. RESEARCH DESIGN AND METHODS This two-center, open-label, three-arm, parallel-group, randomized controlled trial recruited 326 participants diabetes them into...
CRISPR/Cas9, as a well-established gene editing technology, has been applied in numerous model organisms, but its application wild-type E. coli remains limited. Pathogenic coli, major cause of foodborne illnesses and intestinal inflammation humans animals, poses significant global public health threat. The valine-glycine repeat protein G (VgrG) is key virulence factor that enhances pathogenicity. In this study, PCR was used to identify 50 strains carrying the VgrG2 out 83 wild pathogenic...
The high-pathogenicity island (HPI) was initially identified in Yersinia and can be horizontally transferred to Escherichia coli produce yersiniabactin (Ybt), which enhances the pathogenicity of E. by competing with host for Fe3+. Pyroptosis is gasdermin-induced necrotic cell death. It involves permeabilization membrane accompanied an inflammatory response. still unclear whether Ybt HPI cause intestinal epithelial cells undergo pyroptosis contribute gut inflammation during infection. In this...
Hemolysin-coregulated protein 1 (Hcp1) is an effector released by the type VI secretion system (T6SS) in certain pathogenic strains of Escherichia coli (E. coli) that causes apoptosis and contributes to development meningitis. The exact toxic consequences Hcp1 whether it intensifies inflammatory response triggering pyroptosis are yet unknown. Here, utilizing CRISPR/Cas9 genome editing method, we removed gene expressing from wild-type E. W24 examined impact on virulence Kunming (KM) mice. It...
Clinically mild encephalitis/encephalopathy with a reversible splenial lesion (MERS) is clinico-radiological syndrome characterized by transient symptoms of encephalopathy and in the splenium corpus callosum on magnetic resonance imaging (MRI). It often triggered infection. The common pathogens MERS are viruses, especially influenza virus. However, Mycoplasma pneumoniae (M.pneumoniae) relatively rare for MERS. Here we report two paediatric cases M.pneumoniae infection-induced diagnosis...
Type 2 diabetes mellitus (T2DM) is a leading risk factor for the development and progression of chronic kidney disease (CKD). However, an accurate convenient marker early detection appropriate management CKD in individuals with T2DM limited. Recent studies have demonstrated strong correlation between neutrophil-to-lymphocyte ratio (NLR) CKD. Nonetheless, predictive value NLR renal damage type diabetic patients remains understudied.
Anxiety is a common emotional disorder in children. To understand its underlying mechanisms, chronic unpredictable stress (CUS) has been established as model zebrafish. By using the tall tank test, response reliability could be improved adult fish which not confirmed larvae. In addition, increasing evidences have shown that cerebellum plays important roles anxiety. Whether CUS will affect cerebellar neuronal activity remains unknown. We found exposure to larvae (from 10 17 days post...
Background: Tic disorders (TD) are common neuropsychiatric among children and adolescents. It is controversial that trace elements may participate in the pathogenesis of TD. Our study aimed to investigate status zinc (Zn), copper (Cu), iron (Fe), magnesium (Mg) with TD, comparison healthy controls. Methods: The medical records eligible TD normal from January 1 December 31, 2018 outpatient clinic were retrospectively reviewed. clinical information all subjects collected including age, gender,...
<p dir="ltr"><a href="" target="_blank"><b>Objective</b></a></p><p dir="ltr">We aimed to examine the effects of “5:2 regimens” diet (2-day/week energy restriction by formula diet) or exercise high-intensity interval training and resistance training) intervention compared with routine lifestyle education (control) on glycemic control cardiometabolic health among adults overweight/obesity type 2 diabetes.</p><p dir="ltr"><b>Research...
In this paper, an inkjet-printed electrochromic (EC) paper display integrated with passive UHF-RFID tag is introduced as a solution for electronic shelf labels (ESL). To address the system challenges of limited power budget tags and material aging EC display, feedback comparator digital driver proposed based on study electrochromic, bi-stable features display. Modularized baseband different enable conditions clock domains implemented in design level. Moreover, to maintain functions when...
Abstract Background This study aimed to evaluate the efficacy and retention rate of a ketogenic diet (KD) assess factors that influence KD therapy in children with refractory epilepsy (RE). Methods We retrospectively studied 56 RE who accepted from January 2013 December 2019. Patients had ≥50% reduction seizure frequency were defined as responders. The was calculated proportion continued KD/the total number followed up at time enrollment. also analyzed effects different (such gender, initial...
β-Catenin is a key component of the canonical Wnt signaling pathway. It has been shown to have an important role in formation neuromuscular junction. Our previous studies showed that absence β-catenin, resting membrane potential (RMP) depolarized muscle cells and expression α2 subunit sodium/potassium adenosine triphosphatase (α2NKA) reduced. To understand underlying mechanisms, we investigated electrophysiologic properties primary cell line derived from mouse myoblasts (C2C12 cells) were...
Duchenne muscular dystrophy (DMD) is an X-linked autosomal recessive genetic disorder caused by mutations in DMD gene. Approximately 70% of the are deletions or duplications exons, while remaining were minor mutations.We present a 5-year-old boy with typical clinical features DMD. A novel mutation was identified as c.9358_9359insA gene next-generation sequencing. This which origined from mother, generated frameshift and resulted abnormal synthesis protein polypeptide chains.We demonstrated...
This paper presents a phase noise improvement method for fine tuning of type-I ADPLL by exploiting its nonlinear quantization effects. When step approaches the same orders magnitude standard deviation input noise, effects become nonlinear, and additive modeling is no longer applicable. By proper offsetting signals in this case, feedback loop can be very sensitive to frequency deviation. It results larger bandwidth, turn smaller in-band than linear case. A theoretic s-domain model proposed...