- Cardiac, Anesthesia and Surgical Outcomes
- Respiratory Support and Mechanisms
- Intensive Care Unit Cognitive Disorders
- Cardiac Arrest and Resuscitation
- Mechanical Circulatory Support Devices
- COVID-19 Clinical Research Studies
- Cardiac and Coronary Surgery Techniques
- Sepsis Diagnosis and Treatment
- Antifungal resistance and susceptibility
- Frailty in Older Adults
- Nosocomial Infections in ICU
- Cerebrospinal fluid and hydrocephalus
- Hemodynamic Monitoring and Therapy
- Heart Failure Treatment and Management
- Disaster Response and Management
- Cardiac Ischemia and Reperfusion
- Traumatic Brain Injury and Neurovascular Disturbances
- Anesthesia and Pain Management
- Interstitial Lung Diseases and Idiopathic Pulmonary Fibrosis
- Hip and Femur Fractures
- Family and Patient Care in Intensive Care Units
- Healthcare Decision-Making and Restraints
- Long-Term Effects of COVID-19
- Optical Imaging and Spectroscopy Techniques
- Ultrasound in Clinical Applications
University Hospital of Geneva
2013-2025
University of Geneva
2018-2024
Hôpital Beau-Séjour
2024
Ospedale Infermi di Rimini
2022
Sanatorium Kilchberg
2022
See-Spital
2022
Geneva College
2021
University of Bergen
2021
Assistance Publique – Hôpitaux de Paris
2005-2012
Sorbonne Université
2011-2012
Abstract Background Long-term outbreaks of multidrug-resistant Gram-negative bacilli related to hospital-building water systems have been described. However, successful mitigation strategies rarely reported. In particular, environmental disinfection or replacement contaminated equipment usually failed eradicate sources Pseudomonas aeruginosa. Methods We report the investigation and termination an outbreak P. aeruginosa producing VIM carbapenemase (PA-VIM) in adult intensive care unit (ICU) a...
Accurate risk stratification of critically ill patients with coronavirus disease 2019 (COVID-19) is essential for optimizing resource allocation, delivering targeted interventions, and maximizing patient survival probability. Machine learning (ML) techniques are attracting increased interest the development prediction models as they excel in analysis complex signals data-rich environments such critical care.We retrieved data on COVID-19 admitted to an intensive care unit (ICU) between March...
Abstract Purpose Blood culture contamination (BCC) is mainly caused by commensal bacteria, during sample collection. It results in unnecessary antibiotic exposure, prolonged hospitalisation, additional microbiology workup and significant adverse health-economic burden. We aimed to investigate the short- long-term impact of COVID-19 pandemic on incidence BCC. Methods conducted a retrospective, observational cohort study at Geneva University Hospitals (HUG). included all BCCs from January 2018...
We describe the impact of a multifaceted program for decreasing ventilator-associated pneumonia (VAP) after implementing nine preventive measures, including selective oropharyngeal decontamination (SOD).We compared VAP rates during an 8-month pre-intervention period, 12-month intervention and 11-month post-intervention period in cohort patients who received mechanical ventilation (MV) > 48 h. The primary objective was to assess effect on first occurrence, using Cox cause-specific...
In many countries, large numbers of critically ill patients with coronavirus disease 2019 are admitted to the ICUs within a short period time, overwhelming usual care capacities. Preparedness and reorganization ahead wave increase ICU surge capacity may be associated favorable outcome. The purpose this study was report our experience in terms organization anticipation, as well reporting patient characteristics, treatment, outcomes.A prospective observational study.The division intensive at...
Switzerland experienced two waves of COVID-19 in 2020, but with a different ICU admission and treatment management strategy. The timing intubation remains matter debate severe patients. aim our study was to describe the characteristics patients between subsequent who underwent strategy assess whether associated differences mortality. We conducted prospective observational all adult acute respiratory failure due required 9th March 2020 January 2021 intensive care unit (ICU) at Geneva...
COVID-19 patients often present with rapidly progressing acute hypoxemic respiratory failure, requiring orotracheal intubation different prognostic issues. However, ICU specialists lack predictive tools to stratify these patients. We conducted a single-center cross-sectional retrospective study evaluate if the ROX index, measured under non-invasive oxygenation support, can predict mortality in intubated patient cohort. This took place division of intensive care at Geneva University Hospitals...
Most surveillance systems for catheter-related bloodstream infections (CRBSI) and central line-associated (CLABSI) are based on manual chart review. Our objective was to validate a fully automated algorithm CRBSI CLABSI in intensive care units (ICU).
Abstract Anaphylactic reactions at the time of chimeric antigen receptor T (CAR‐T) cell infusion are adverse events that have not been reported in pivotal clinical trials or real‐world series. We report case patient with severe anaphylaxis cardiac arrest after tisagenlecleucel injection for Diffuse Large B Lymphoma, who recovered resuscitation and intensive care treatment; we also conducted a Food Drug Administration Adverse Event Reporting System database analysis found several cases...
Introduction. Organophosphate poisoning by oral or inhalation routes is characterized a typical time-course of clinical features. Case presentation. We report case subcutaneous chlorpyrifos self-injection leading to delayed cholinergic phase, prolonged coma, and severe permanent neurologic injury with electrophysiological patterns suggestive overlapping intermediate syndrome distal peripheral neuropathy. Time-course severity features were not altered either atropine pralidoxime...
Abstract Background Influenza‐associated pulmonary aspergillosis (IAPA) is an important complication of severe influenza with high morbidity and mortality. Methods We conducted a retrospective multicenter study in tertiary hospitals Switzerland during 2017/2018 2019/2020 seasons. All adults PCR‐confirmed infection treatment on intensive‐care unit (ICU) for >24 h were included. IAPA was diagnosed according to previously published clinical, radiological, microbiological criteria. assessed...
STUDY AIM: The surge of admissions due to severe COVID-19 increased the patients-to-critical care staffing ratio within ICUs. We investigated whether daily level was associated with an risk ICU mortality (primary endpoint), length stay (LOS), mechanical ventilation and evolution disease (secondary endpoints). METHODS: employed a retrospective multicentre analysis international Risk Stratification in patients (RISC-19-ICU) registry, limited period between March 1 May 31, 2020, Switzerland....