- Interstitial Lung Diseases and Idiopathic Pulmonary Fibrosis
- Occupational and environmental lung diseases
- Acupuncture Treatment Research Studies
- Muscle activation and electromyography studies
- Migraine and Headache Studies
- Liver Disease Diagnosis and Treatment
- Circular RNAs in diseases
- Motor Control and Adaptation
- Myofascial pain diagnosis and treatment
- Genetic Associations and Epidemiology
- Gut microbiota and health
- Nutritional Studies and Diet
- Connective Tissue Growth Factor Research
- Liver physiology and pathology
- Medical Research and Treatments
- Tea Polyphenols and Effects
- Electrochemical Analysis and Applications
- Thyroid Disorders and Treatments
- Ferroptosis and cancer prognosis
- Respiratory Support and Mechanisms
- Psychosomatic Disorders and Their Treatments
- Suicide and Self-Harm Studies
- Hemodynamic Monitoring and Therapy
- Cancer-related molecular mechanisms research
- Chronic Kidney Disease and Diabetes
Chengdu University of Traditional Chinese Medicine
2014-2024
Kailuan General Hospital
2019
Sun Yat-sen University
2014-2018
Guilin University of Electronic Technology
2016
Objective: To examine the causal effect of potentially modifiable risk factors contributing to migraine pathogenesis. Methods: We performed Mendelian randomization analyses and acquired data from United Kingdom Biobank, FinnGen MRC IEU OpenGWAS infrastructure. An inverse-variance weighted (IVW) model was used relationship between 51 in 3215 participants with without aura (MwoA), 3541 (MwA), 176,107 controls. adopted a Bonferroni-corrected threshold p = 9.8 × 10–4 (.05 divided by exposures)...
<b><i>Background and Objectives:</i></b> This study was to characterize the association of cumulative exposure increased high-sensitivity C-reactive protein (hs-CRP) with chronic kidney diseases (CKD). <b><i>Methods:</i></b> We included 35,194 participants hs-CRP measured at three examinations in 2006, 2008, 2010. Participants were classified into nonexposed group (hs-CRP &#x3c;3.0 mg/L all 3 examinations), 1-exposed ≥3.0 1 2-exposed 2...
Aging alters muscular coordination patterns. This study aimed to investigate aging-related changes in the of agonist and antagonist muscles from two aspects, activities individual inter-muscular coupling. Eighteen young subjects 10 elderly were recruited modulate muscle activity track a target during voluntary isometric elbow flexion extension. Normalized activation fuzzy entropy (FuzzyEn) applied depict biceps triceps. Mutual information (MI) was utilized measure coupling between The...
To observe the clinical efficacy and safety of Traditional Chinese Medicine (TCM) combined with Western (WM) in patients diabetic acute ischemic stroke.Ninety stroke were randomly divided into a treatment group control group. The 45 given standardized TCM WM. They received corresponding oral decoctions three times daily, according to their syndromes, along basic western medical treatment. non-standardized an decoction for promotion blood circulation inhibit hemostasis, regardless treatments...
Background. There is no effective therapy for silicosis, and Dahuang Zhechong pill (DHZCP), an ancient Chinese medicine prescription, may have a therapeutic effect on silicosis. This study aims to verify the efficacy safety of DHZCP in Methods. randomized controlled clinical trial done at Panzhihua Second People’s Hospital (Panzhihua City, Sichuan Province, China). Participants diagnosed with silicosis were recruited conventional treatment group (CG) or combined (DG). Forced vital capacity %...
Background Alzheimer's disease (AD) is a degenerative of the nervous system. Observational studies have found an association between plant food intake and AD. However, it unclear whether this influenced by confounding factors. We aimed to explore causal relationship plant-based diet risk AD using two-sample Mendelian randomization.
Electrode configuration is an important issue in the continuous measurement of respiration using impedance pneumography (IP). The robust usually confirmed by comparing amplitude IP signals acquired with different electrode configurations, while relative change waveform and effects body posture respiratory pattern are ignored. In this study, volume simultaneously from 8 healthy subjects supine, left lying, right lying prone postures, asked to perform four patterns including free breathing,...
Acupuncture is an effective and safe therapy for patients with migraine without aura (MwoA), but only 41-59% of show improvement this treatment. Screening positive responders to acupuncture treatment MwoA can ensure that healthcare resources be appropriately targeted specific who would most benefit. The objective study determine whether the structure functional activity in certain brain regions predict analgesia response receive treatment.A total 72 healthy controls (HCs) will enrolled...
Depression, a prevalent psychiatric disorder, presents serious health risk to humans. Increasing evidence suggested that the gut microbiota and 5-hydroxytryptamine (5-HT) pathway both contribute significantly depression. This research aimed investigate how Corydalis yanhusuo polysaccharides (CYP) could potentially alleviate depression induced by chronic unpredictable mild stress in mice, as well its underlying mechanism. The sucrose preference test, tail suspension forced swimming test were...
Dahuang Zhechong pills (DHZCP) is a classic Chinese medicinal prescription in "Treatise on Cold Pathogenic and Miscellaneous Diseases (Shanghan Zabing Lun)," it has the function of tonifying blood, nourishing Yin, removing blood stasis. Previous studies have shown that DHZCP could alleviate SiO2 induced pulmonary fibrosis mice. This study aims to further explore preventive therapeutic effects against silicosis underlying mechanisms vitro.We used experimental model SiO2-induced MH-S cells...
Introduction: The variability and complexity of handgrip forces in various modulations were investigated to identify post-stroke changes force modulation, extend our understanding stroke-induced deficits. Methods: Eleven subjects ten age-matched controls performed voluntary grip control tasks (power-grip tasks) at three contraction levels, stationary dynamometer holding (stationary tasks). Variability described with root mean square jerk (RMS-jerk) fuzzy approximate entropy (fApEn),...
Since DHZCP had significant inhibitory effects on liver and kidney fibrosis, we hypothesize that could also inhibit pulmonary fibrosis. Therefore, the aim of this study is to examine effect silicosis, a type fibrosis caused by silica dust, its underlying mechanism. Pulmonary was induced inhalation (SiO2) dust in mice which were then randomly divided into 5 groups: model group, high-dose medium-dose low-dose group Tetrandrine group. The normal control not exposed SiO2 dust. After 28 days...
Muscle coordination during isometric elbow contraction was investigated in this study order to understand the agonist-to-antagonist dependency. 15 healthy subjects were recruited and instructed perform target-directed flexion extension. Electromyography (EMG) signals from both biceps triceps captured. Root mean square (RMS) of EMG applied reflect muscle activation level fuzzy approximate entropy (fApEn) utilized represent complexity signals. Mutual information (MI) analyze inter-dependency...
Acupuncture and fremanezumab are second-line treatments for migraine prophylaxis. We aimed to compare acupuncture with in the preventive treatment of episodic by using a matching-adjusted indirect comparison analysis (MAIC).We acquired participant-level data from an trial recruiting 302 participants summary-level 875 (290 received monthly [MF] 291 single-dose [SF]). The primary outcome was mean reduction headache days. secondary outcomes were moderate-to-severe days, days acute medication,...
Ethnopharmacological relevance: Dahuang Zhechong Pills (DZP) is a classic Chinese medicinal prescription in 'The Synopsis of Prescriptions the Golden Chamber (Jin Gui Yao Lüe)'. In China, it was officially approved by Association integrative medicine for prevention and treatment liver fibrosis. At present, recorded Pharmacopoeia clinically used to treat gynecopathy, hepatic diseases, atherosclerosis multiple organ fibrosis.Aim study: Based on early clinical observation that DCP can...