A5100322620- Nanoplatforms for cancer theranostics
- Multiple Myeloma Research and Treatments
- Cancer-related molecular mechanisms research
- Advanced oxidation water treatment
- Advanced Photocatalysis Techniques
- Cancer therapeutics and mechanisms
- RNA modifications and cancer
- Arsenic contamination and mitigation
- Advanced Nanomaterials in Catalysis
- Effects of Radiation Exposure
- DNA Repair Mechanisms
- Photodynamic Therapy Research Studies
- Environmental remediation with nanomaterials
- RNA Interference and Gene Delivery
- MicroRNA in disease regulation
- Protein Degradation and Inhibitors
- RNA Research and Splicing
- Photoacoustic and Ultrasonic Imaging
- Advanced biosensing and bioanalysis techniques
- Venomous Animal Envenomation and Studies
- Nanoparticle-Based Drug Delivery
- Metal-Organic Frameworks: Synthesis and Applications
- Virus-based gene therapy research
- Wastewater Treatment and Nitrogen Removal
- Cancer Immunotherapy and Biomarkers
South China University of Technology
2016-2025
Guangdong Medical College
2025
Peking University
2020-2024
Shanghai Jiao Tong University
2017-2024
Harbin University of Commerce
2024
Peking University Cancer Hospital
2021-2024
Tianjin Medical University
2022-2024
Shanghai Sixth People's Hospital
2022-2024
Anhui Academy of Agricultural Sciences
2023-2024
Tianjin Medical University General Hospital
2024
Real-time monitoring of vessel dysfunction is great significance in preclinical research. Optical bioimaging the second near-infrared (NIR-II) window provides advantages including high resolution and fast feedback. However, reported molecular dyes are hampered by limited blood circulation time (~ 5-60 min) short absorption emission wavelength, which impede accurate long-term monitoring. Here, we report a NIR-II molecule (LZ-1105) with beyond 1000 nm. Thanks to long (half-life 3.2 h),...
Western blotting (WB), enzyme-linked immunosorbent assay (ELISA) and flow cytometry (FC) have long been used to assess quantitate relative protein expression in cultured cells tissue samples. However, WB ELISA limited ability meaningfully levels tissues with complex cell composition, while dissociation followed by FC is not feasible when limiting and/or difficult isolate. While detection using immunofluorescent (IF) probes has traditionally considered a qualitative technique, advances probe...
In this work, a novel and effective heterogeneous catalyst, the metal–organic framework MIL-53(Fe), has been synthesized for purpose of activating persulfate (PS).
Smoldering myeloma (SMM) is associated with a high-risk of progression to (MM). We report the results study 82 patients both targeted sequencing that included capture immunoglobulin and MYC regions. By comparing these newly diagnosed (MM) we show fewer NRAS FAM46C mutations together adverse translocations, del(1p), del(14q), del(16q), del(17p) in SMM consistent their role as drivers transition MM. KRAS are shorter time (HR 3.5 (1.5-8.1), p = 0.001). In an analysis change clonal structure...
Polydopamine nanoparticles camouflaged with stem cell membranes could effectively target tumor sites and showed excellent performance in synergistic chemoimmunotherapy for PCa bone metastases.
The formation of atherosclerotic plaques is the root cause various cardiovascular diseases (CVDs). Effective CVD interventions thus call for precise identification to aid clinical assessment and treatment such diseases. In this study, we introduced a dual-analyte sequentially activated logic fluorescence reporting system CNN2-B precisely identify in vivo. This probe was achieved by creating dual-locked fluorescent sensor that permits highly specific sensitive detection peroxynitrite lipid...
Abstract PD-1/PD-L1 blockade therapy that eliminates T-cell inhibition signals is successful, but poor benefits are often observed. Increasing infiltration and quantity of inhibitors in tumor can improve efficacy remains challenging. Here, we devise tumor-specific gene nanomedicines to mobilize cells secrete CXCL9 (T-cell chemokine) anti-PD-L1 scFv (αPD-L1, PD-L1 blocking agent) for enhanced immunotherapy. The tyrosinase promoter-driven NP Tyr-C9AP specifically co-express αPD-L1 melanoma...
Cell-cultured meat, which is obtained by adsorbing cells on the three-dimensional scaffold, considered a potential solution to animal welfare issues. Edible and safe cell-cultured meat scaffolds are key part of its research. Soy protein isolate (SPI) hydrogel has network structure been studied for L929 cell culture because non-toxicity biocompatibility. However, toughness mechanical properties SPI not enough bear requirements cultivation. In this paper, sodium alginate (SA) was added...
ConspectusNanomedicine is an interdisciplinary science that involves chemistry, materials, physics, engineering, biology, and medicine. The main focus of nanomedicine on drug carriers: how to improve efficacy reduce side effects. In order further the synergistic detoxifying effects nanomedicines, scientists have adopted a multifunctional integration strategy. However, versatility brings complex components ignores between components. lack in-depth research bioactivities nanocarriers hinders...