A5009969222- Blood transfusion and management
- Venous Thromboembolism Diagnosis and Management
- Blood groups and transfusion
- Hemoglobinopathies and Related Disorders
- Erythrocyte Function and Pathophysiology
- Blood donation and transfusion practices
- Blood disorders and treatments
- Cancer Treatment and Pharmacology
- Hematopoietic Stem Cell Transplantation
- Erythropoietin and Anemia Treatment
- Iron Metabolism and Disorders
- Platelet Disorders and Treatments
- Trauma, Hemostasis, Coagulopathy, Resuscitation
- Clinical Laboratory Practices and Quality Control
- Neonatal Health and Biochemistry
- Electronic Health Records Systems
- Diabetes Treatment and Management
- Central Venous Catheters and Hemodialysis
- Acute Myeloid Leukemia Research
- Acute Ischemic Stroke Management
- Blood Coagulation and Thrombosis Mechanisms
- Sepsis Diagnosis and Treatment
- Long-Term Effects of COVID-19
- COVID-19 Clinical Research Studies
- SARS-CoV-2 and COVID-19 Research
Western University
2018-2024
London Health Sciences Centre
2019-2024
Institute for Transfusion Medicine
2024
McMaster University
2011-2023
Canadian Blood Services
2016-2023
Seattle University
2018
McMaster Children's Hospital
2016
Queen's University
2010
Children's Hospital of Eastern Ontario
2006
Abstract The efficacy of convalescent plasma for coronavirus disease 2019 (COVID-19) is unclear. Although most randomized controlled trials have shown negative results, uncontrolled studies suggested that the antibody content could influence patient outcomes. We conducted an open-label, trial adults with COVID-19 receiving oxygen within 12 d respiratory symptom onset ( NCT04348656 ). Patients were allocated 2:1 to 500 ml or standard care. composite primary outcome was intubation death by 30...
Parenteral anticoagulants may improve outcomes in patients with cancer by reducing risk of venous thromboembolic disease and through a direct antitumour effect. Study-level systematic reviews indicate reduction thromboembolism provide moderate confidence that small survival benefit exists. It remains unclear if any patient subgroups experience potential benefits. First, we will perform comprehensive search MEDLINE, EMBASE The Cochrane Library, hand scientific conference abstracts check...
BACKGROUND The optimal method of providing transfusion medicine (TM) education has not been determined. Transfusion Camp was established in 2012 at the University Toronto as a centrally delivered TM program for postgraduate trainees. impact on knowledge, attitudes, and self‐reported behavior evaluated. METHODS Didactic lectures (delivered locally, by webinar, or recorded) locally facilitated team‐based learning seminars were over 5 days during academic year to 8 sites: 7 Canada 1 United...
Individuals with sickle cell disease (SCD) and central venous catheters (CVC) are at high risk for thromboembolism (VTE). Minimal data exist regarding the use of anticoagulation as thromboprophylaxis VTE in this demographic, a result, clinical equipoise exists. Prophylactic dose rivaroxaban, direct oral anticoagulant, is efficacious safe other demographics, may be an optimal agent SCD CVC. Prior to conducting full trial assess rivaroxaban CVC, pilot study needed gauge its feasibility....
Plasma is often transfused to patients with bleeding or requiring invasive procedures and abnormal tests of coagulation. Chart audits find half plasma transfusions unnecessary, resulting in avoidable complications costs. This multicentre electronic audit was conducted determine the proportion without an indication and/or at a sub-therapeutic dose.Data were extracted on adult inpatients 2017 five academic sites from hospital chart, laboratory information systems Canadian Institute for Health...
St reptococcus pyogenes is an uncommon cause of community-acquired pneumonia in children. Further, its clinical course comparison to caused by Streptococcus has not been previously highlighted.We reviewed medical records children 0-18 years age from April 1983 2005, with discharge diagnoses invasive disease group A streptococcus (GAS) (Streptococcus pyogenes), or (SP) pneumonia. Data were extracted the charts, and a characteristics between 2 etiologies was performed. Confirmed required blood...
BACKGROUND Although not supported by strong evidence, premedication (pretransfusion medication) is commonly prescribed to patients who have had a transfusion reaction. The research questions were: 1) What are Canadian pediatric practitioners' views and practices regarding 2) what barriers reducing overuse in pediatrics? STUDY DESIGN AND METHODS An online survey targeted hematology/oncology, emergency medicine, general surgery, intensive care, cardiac care practitioners all 16 tertiary...
Background & Objectives Alloimmunization rates following red blood cell ( RBC ) transfusion in paediatric oncology are not known. This study aimed to: (1) describe frequency and specificity of alloantibodies patients after transfusions; (2) determine the effect chemotherapy on alloimmunization rate. Materials Methods Retrospective cohort at a tertiary care hospital is evaluated by two groups: control group, without cancer; who received chemotherapy. was defined as clinically significant...
Abstract Aims and Objectives The aim of this study was to investigate nurse perspectives on transfusion‐related adverse reaction reporting practices. Background Transfusion‐related is an essential component hemovigilance in Canada, but rates vary under‐reporting minor reactions exists. To our knowledge, the first report nursing attitudes. Design This qualitative descriptive explored practices by conducting one‐on‐one interviews with nurses ( n = 25) working adult oncology inpatient...
BACKground: In the past 30 years, rate of obesity has risen considerably among Canadian children.Paediatric hospitals are in a unique position to model healthy environments children.oBJeCtive: To obtain an overview active living (HAL) policy and practice paediatric hospitals.MetHodS: Working partnership with local Paediatric Society HAL champions Association Health Centres liaisons, nationwide survey was conducted 2006/2007 identify eating, physical activity smoking cessation practices all...