A5016784741- Parathyroid Disorders and Treatments
- Dialysis and Renal Disease Management
- Venous Thromboembolism Diagnosis and Management
- Central Venous Catheters and Hemodialysis
- Heparin-Induced Thrombocytopenia and Thrombosis
- Restless Legs Syndrome Research
- Bone health and treatments
- Acute Ischemic Stroke Management
- Electrolyte and hormonal disorders
- Atrial Fibrillation Management and Outcomes
- Diabetes Treatment and Management
- Erythropoietin and Anemia Treatment
- Genetic Syndromes and Imprinting
- Diabetes, Cardiovascular Risks, and Lipoproteins
- Dysphagia Assessment and Management
- Blood donation and transfusion practices
- Neurological Complications and Syndromes
- Toxoplasma gondii Research Studies
- Intramuscular injections and effects
- Pregnancy and Medication Impact
- Phonocardiography and Auscultation Techniques
- Vascular Malformations and Hemangiomas
- Aging, Elder Care, and Social Issues
- Hemophilia Treatment and Research
- Blood disorders and treatments
Mito Saiseikai General Hospital
2014-2015
Tokyo Women's Medical University
2013
Isuzu Advanced Engineering Center (Japan)
2010
University of Hyogo
2010
Japanese Society for Dialysis Therapy
2001-2006
Edogawa Hospital
1980-1999
Kanagawa Cancer Center
1996
Kanagawa Prefectural Hospital Organization
1996
Hyogo Medical University
1987
A statistical survey of 3932 nationwide hemodialysis (hereafter, dialysis) facilities was carried out at the end 2004, and 3882 (98.73%) responded. The population undergoing dialysis 2004 248 166, an increase 10 456 patients (4.4%) from that 2003. number per million people 1943.5. crude death rate 2003 to 9.4%. mean age who underwent in 65.8 years, total 63.3 years. percentage distribution according a newly underlying disease showed 41.3% had diabetic nephropathy 28.1% chronic...
A statistical survey at the end of 1999 by Japanese Society for Dialysis Therapy resulted in responses from 3, 220 (99.66%) 231 institutions providing dialysis. The found 197, 213 chronic dialysis patients Japan, an increase 6.4% (11, 891 patients) 1998 survey. a slight decrease gross annual mortality percentage compared to (9.7%). mean age newly introduced increased 63.4±13.9 (±SD) years 1999. population was 60.6±13.3 years. primary diseases leading were diabetic nephropathy (36.2%) and...
Abstract Background Under-recognition of depression is common in many countries. Education medical staff, focusing on their attitudes towards depression, may be necessary to change behavior and enhance recognition depression. Several studies have previously reported toward among general physicians. However, little known about non-psychiatric doctors Japan. In the present study, we surveyed doctors’ attitude Methods The inclusion criteria participants study were as follows: 1) Japanese 2)...
The aim of this study was to determine the frequency heparin/platelet factor (PF) 4 complex antibodies in 305 uremic patients treated with chronic intermittent hemodialysis using unfractionated heparin or low-molecular-weight for 3 months. Heparin-induced thrombocytopenia (HIT) were detected by ELISA 7 (2.3%) who had no history HIT. Two abruptly developed HIT associated formation clots extracorporeal circuit after they found be carrying antibodies. These suspected have a similar trigger: an...
The annual statistical survey conducted at the end of 2000 by Japanese Society for Dialysis Therapy collected responses from 3, 358 (99.94%) 360 institutions. Japan's total dialysis patient population year 2000, as identified this survey, was 206, 134, an increase 8, 921 (4.5%) over 1999. This translates to 1, 624.1 patients per million population. crude mortality rate 9.4% period starting 1999 and ending 2000. mean age initiation treatment 63.8 (±13.9; ±S. D.) years; overall 61.2 years...
The aim of this study was to determine whether treatment with β(2)-microglobulin adsorption column (Lixelle) affects bone cysts and clinical symptoms in patients dialysis-related amyloidosis (DRA).Radiographic changes the number area wrist hip joint were compared between 39 hemodialysis (HD) treated Lixelle (Lixelle group) 28 HD conventional therapy as retrospective control (HD group). Clinical DRA also evaluated.In group, cystic joints significantly decreased, although these parameters not...
Hemodialysis leukopenia was studied using various dialyzers and membranes. We found that with cellulosic membranes caused marked leukopenia, but in recently developed non membranes, its occurrence significantly less. Additionally, our results showed a newly cellulose acetate membrane to correlate well the regarding spite of it being derivative cellulose.The extent white blood cell decrease seemed inversely an increase ultrafiltration rate per area dialyzer.The relationship between hypoxemia...
A pharmacokinetic study of natural human interferon-α (IFN-α) was conducted in hemodialysis patients. Natural IFN-α intramuscularly (i.m.) administered to 8 patients at a single dose 5 million IU and 7 undergoing the same once daily for successive days. The serum antiviral activity determined by cytopathic effect bioassay. In study, reached maximum (Cmax) 56.4 +/- 33.3 IU/ml 8.3 2.7 h after dosing, area under concentration-time curve (AUC0-24h) 957.2 601.8 h/ml. Cmax AUC0-24h values day...
透析患者に対し，治療を円滑に行うために必要なシャントの日常管理のうちでも，特に狭窄の診断は極めて重要である．シャント音の聴診はシャント狭窄を簡便に診断する方法として日常的に用いられている．臨床経験上，狭窄の進行に伴って高調なシャント音が聴診されることが知られているが，この診断には客観的な基準がなく，聴診者の主観に頼っているのが現状である．そこでわれわれはこの診断基準の確立に向けた基礎的研究として，シャント音を周波数解析し，狭窄度と周波数スペクトルの関係について解明することを試みた．方法としては，まず患者のシャント（動静脈吻合）の吻合部より中枢部に向けて3～6箇所の部位で複数のシャント音を記録し，短時間フーリエ変換により周波数スペクトルを算出した．次にシャント狭窄度とシャント音の周波数スペクトルとの関係をスペクトルの平均値の有意差により解析した．その結果，吻合部（シャント狭窄部より上流域）および狭窄部上では，狭窄の進行に伴い高周波数帯域のスペクトルの割合が有意に大きいことが確認された．一方，中央部（狭窄部より下流域）では基本的に狭窄度と周波数帯域との間に有意差は確認できなかったが，...
Introduction Disulfiram (DSF) has been used for nearly 70 years as an antidrug and is clinically safe. Recently, it attracted widespread attention, because was shown through screening to be effective anticancer agent. 1) However, further improvement of the efficacy DSF required before can a therapeutic In this study, we focused on metal diethyldithiocarbamate complexes formed by ion (Cu 2+ , Fe 3+ ), respectively, improve drug applying photodynamic therapy. It aimed enhance photoresponses...
We describe a 43-year-old male patient with congenital antithrombin III deficiency requiring hemodialysis due to extension of venous thrombus from recurrent deep vein thrombosis. During dialysis adequate heparinization, the often revealed clot formation in extracorporeal circuit resulting unexpected discontinuation dialysis. When either combination concentrate + heparin or newly developed synthetic preparation, MD805, was administered during dialysis, he could be uneventfully dialyzed two regimens.
Purpose Phosphorus removal is a major issue to assess for physicians engaging in hemodialysis. A pseudo-one-compartment model was reported as novel phosphorus kinetics. We aimed evaluate the adequacy of this from standpoint total mass removed during prolonged treatment. Methods Dialysate collected 6-h hemodialysis and hemodiafiltration treatment 5 patients. Later-phase (from 4 6 h) dialysate separately. Mobilization clearance (K m dialyzer (K) were calculated by simple arithmetic operations...
在宅血液透析における患者による自己穿刺の容易性を高めるため，自己穿刺補助具を開発した．補助具のプロトタイプは三次元立体造形技術により，アクリロニトリル・ブタジエン・スチレン共重合体（ABS）樹脂を用いて製造された．当該補助具は，台座部，延設部，アーム部，突起部，および血管を圧迫固定するための弾性的な付勢手段としてのトーションバネから主に構成された．穿刺する際，アーム部をトーションバネの付勢力に抗して揺動させて腕を挿通し，突起部にて血管を押圧する．さらに，その押圧状態から患者の腕を穿刺方向にわずかにずらすことにより，血管を伸展固定できるように設計された．
We started our home hemodialysis (HHD) program in July 2005 and have been promoting overnight HHD. As more than 6 years passed since we HHD program, review 8 patients (5 males 3 females). Their underlying disease differs each none diabetic nephropathy. average age was 49.2 ± 6.0 (mean SD). Average duration of dialysis treatment, HHD, 9.4 4.4, 3.5 2.4, 2.2 1.7 years, respectively. treatment time per session 6.9 0.8 h/treatment, days weekly 4.5 days/week, 31.2 7.0 h/week. Laboratory data were...
For twenty long-term hemodialysis patients with medically uncontrolled hyperparathyroidism, subtotal parathyroidectomy (PTX) was performed and histological examination done for 17 out of them, suspected thyroid disease from operative findings. Thyroid carcinomas were found in 5 by biopsied specimens thyroids. Histological findings follicular (2 cases) papillary types (3 cases). In all cases, occult state the sizes 4 cases small being a diameter less than 10mm. Among others, adenoma chronic...
Object-oriented software development is a powerful methodology for of large hospital information systems. We think use-case driven approach particularly useful the development. In use-cases approach, are documented at first stage in process and they used through whole steps variety ways. Therefore, it important to exchange share usecases make effective use them overall lifecycle process. this paper, we propose method sharing exchanging models between applications, developers, projects....
［目的］透析妊婦は切迫流産に対する塩酸リトドリンの使用頻度が高いが透析除去率の報告はない．塩酸リトドリンを投与した透析妊婦で塩酸リトドリンクリアランス（CL），除去率，ダイアライザCLを計算した．［症例］36歳女性，透析歴5年．妊娠20週4日から切迫兆候を認め塩酸リトドリン投与．血液透析（HD）直後に症状悪化し，透析時に約25％増量投与し血液濾過透析（HDF）に変更，27週6日で経腟分娩に至った．［方法］HD（APS-15MD，QB 180 mL/min，QD 500 mL/min），HDF（サブラッドBD8L® （前希釈），APS-15MD，QB 450～500 mL/min，QF 33 mL/min）のダイアライザ前後，HDFで透析前，2時間目，終了4時間目に採血施行．塩酸リトドリンを非透析時126 μg/min，透析時160 μg/minで投与し患者側血中濃度，ダイアライザ出口側濃度，ヘマトクリット，血液流量および濾液流量を用いて，血漿基準CLを算出した．［結果］HDF時の塩酸リトドリン血中濃度は透析前62.03 ng/mL，2時間目69.08...