Hao Li

ORCID: 0000-0002-1717-8302
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About
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Research Areas
  • Wound Healing and Treatments
  • Electrospun Nanofibers in Biomedical Applications
  • Stroke Rehabilitation and Recovery
  • Periodontal Regeneration and Treatments
  • Reconstructive Surgery and Microvascular Techniques
  • Diabetic Foot Ulcer Assessment and Management
  • Orthopedic Surgery and Rehabilitation
  • Antimicrobial agents and applications
  • 3D Printing in Biomedical Research
  • Biological and pharmacological studies of plants
  • Laser Applications in Dentistry and Medicine
  • Toxic Organic Pollutants Impact
  • Musculoskeletal Disorders and Rehabilitation
  • Heme Oxygenase-1 and Carbon Monoxide
  • Silk-based biomaterials and applications
  • Autophagy in Disease and Therapy
  • Skin and Cellular Biology Research
  • Medical and Biological Ozone Research
  • Global Health and Surgery
  • Air Quality and Health Impacts
  • Spine and Intervertebral Disc Pathology
  • Surgical site infection prevention
  • Nanocomposite Films for Food Packaging
  • Acute Ischemic Stroke Management
  • Heavy Metal Exposure and Toxicity

First Affiliated Hospital of Kunming Medical University
2025

Kunming Medical University
2025

Xiamen University
2024

Wenzhou Medical University
2016-2023

Lishui City People's Hospital
2012-2023

Peking University
2023

Beijing Institute of Technology
2021-2022

Ministry of Industry and Information Technology
2021

Weifang Medical University
2020

Henan Provincial People's Hospital
2019

It is imperative to develop a wound dressing that can effectively treat bacterial infection in the location and speed up healing. In this study, chitosan (CS) microspheres with core–shell structure were prepared using high-voltage electrostatic drop technology. The antimicrobial polypeptide (PonG1) bFGF, encapsulated core of CS microsphere. preparation was studied by changing parameters. surface morphology release quantities PonG1 bFGF observed detected. vivo experiments conducted study...

10.1016/j.matdes.2021.109683 article EN cc-by-nc-nd Materials & Design 2021-03-30

The diabetic foot ulcer (DFU) may be associated with late healing and septic manifestation, subsequently lead to amputation which is an overpriced incident. Neferine alkaloid found lotus. possesses many physiological functions such as anti-inflammatory, antioxidant, antimicrobial activity anticancer effect. aim of the present study was evaluate effect topical application based on neferine, in streptozotocin-induced incision wound models rats. data demonstrated activities via macroscopic,...

10.1080/21691401.2019.1699814 article EN cc-by Artificial Cells Nanomedicine and Biotechnology 2019-12-18

Abstract Skin wound healing is a continuous and complex process affected by many factors. Growth factors play an important role in the of healing. Local application growth can significantly promote However, degradation time dependence require appropriate delivery systems to help them In recent years, dressing products with hydrogels as matrix materials or main components have shown obvious advantages promoting By modifying hydrogel combining it other that are beneficial healing, effect be...

10.1515/ntrev-2022-0122 article EN cc-by Nanotechnology Reviews 2022-01-01

This study aims to investigate the role of hypercalciuria and pyroptosis in formation calcium oxalate kidney stones. Bioinformatics analysis was performed compare correlation scores cell adhesion between Randall's plaques normal tissues from stone patients. For vitro experiments, we investigated effects high concentrations Ca2+ on levels renal tubular epithelial cells examined crystal aggregation environment by knockdown overexpression key gene, GSDMD, verified concentration levels, injury,...

10.1038/s41598-025-91460-8 article EN cc-by-nc-nd Scientific Reports 2025-02-24

The development of an effective delivery vehicle that gives rise to a microenvironment promotes skin regeneration remains challenge in the field stem cell-based therapeutic strategy for tissue engineering. Here, we fabricated photo-crosslinkable hydrogel based on decellularized dermal matrix (DDM) combined with o-nitrobenzene-modified hyaluronic acid (HA-NB). HA-NB/DDM hydrogels can be crosslinked situ under UV ultraviolet light irradiation and adhere strongly surrounding tissue. Results...

10.1016/j.matdes.2020.109152 article EN cc-by-nc-nd Materials & Design 2020-09-16

There is a high incidence of acute and chronic skin defects caused by various reasons in clinically practice. The repair functional reconstruction have become major clinical problem, which needs to be solved urgently. Previous studies shown that fibroblast growth factor 10 (FGF10) plays role promoting the proliferation, migration, differentiation epithelial cells. However, little known about effect FGF10 on recovery process after damage. In this study, we found expression endogenous was...

10.1155/2020/8586314 article EN cc-by Oxidative Medicine and Cellular Longevity 2020-12-07

Abstract Persistent inflammation and disrupted immunoregulation are critical factors in impeding diabetic wound healing. While immunoregulatory hydrogel dressings hold significant promise for clinical applications healing, the current application often demands intricate interventions high‐cost treatments involving cytokines cell therapies. The development of single component hydrogels remains a complex challenge. To address this issue, an active peptide with properties targeting TLR4/NF‐kB...

10.1002/adhm.202400391 article EN Advanced Healthcare Materials 2024-04-03

Skin wound healing is a dynamic and complex process that involves multiple physiological cellular events. Grape seed proanthocyanidins (GSP) have strong anti-oxidation elimination of oxygen free radicals, been shown to significantly promote healing, but the underlying mechanism remains unclear. Studies indicated reactive species (ROS) acts as an upstream signal induce mitophagy, suggesting GSP can regulate mitophagy through pathway. This study aimed investigate whether regulates by...

10.1016/j.abb.2023.109790 article EN cc-by-nc Archives of Biochemistry and Biophysics 2023-10-17

The ulnar coronoid process plays a central role in maintaining elbow stability. Some of its fractures were often combined with injury bone and ligament. Arthroscopy enables perfect visualization to allow anatomical repair. From January 2012 December 2013, six patients (four males, two females) mean age 26.6 years treated. left right ulnas involved four patients, respectively. All suffered from ipsilateral subluxation the without associated radial fracture. According Regan Morrey fracture...

10.1186/s13018-016-0505-8 article EN cc-by Journal of Orthopaedic Surgery and Research 2017-01-18
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