- Nutritional Studies and Diet
- Parathyroid Disorders and Treatments
- Consumer Attitudes and Food Labeling
- Obesity, Physical Activity, Diet
- Bone health and treatments
- Agriculture Sustainability and Environmental Impact
- Food Waste Reduction and Sustainability
- Vitamin D Research Studies
- Trace Elements in Health
- Heavy Metal Exposure and Toxicity
- Bone health and osteoporosis research
- Effects and risks of endocrine disrupting chemicals
- Mercury impact and mitigation studies
- Nutrition, Genetics, and Disease
- Dialysis and Renal Disease Management
- Trauma and Emergency Care Studies
- Heavy metals in environment
- Dye analysis and toxicity
- Air Quality and Health Impacts
- Bone and Joint Diseases
- Mechanical Circulatory Support Devices
- Cardiac, Anesthesia and Surgical Outcomes
- Diabetes Treatment and Management
- Sodium Intake and Health
- Renal function and acid-base balance
Universidade do Porto
2009-2025
Polytechnic Institute of Porto
2025
i3S - Instituto de Investigação e Inovação em Saúde, Universidade do Porto
2016-2024
Instituto Politécnico de Leiria
2024
Centro Hospitalar do Porto
2022
Instituto Superior Politécnico do Oeste
2022
University College London
2022
University College Hospital
2022
Hospitais da Universidade de Coimbra
2022
Universidad del Norte
2022
Current food systems compromise many environmental impact boundaries, and a dietary transition towards sustainable patterns is needed. The definition of policies to promote the implies accurate knowledge choices' impact. For its assessment, life cycle assessment (LCA) has been employed, but methodological heterogeneity limited access LCA data hinder comprehensive comparisons. Several publicly accessible standardized foods’ databases have developed address these challenges. However,...
Calcimimetics decrease parathyroid hormone (PTH) secretion in patients with secondary hyperparathyroidism. The PTH should cause a reduction bone turnover; however, the direct effect of calcimimetics on cells, which express calcium-sensing receptor (CaSR), has not been defined. In this study, we evaluated effects CaSR activation by calcimimetic (AMG 641) vitro and vivo. To create "clamp," total parathyroidectomy was performed rats without uremia induced 5/6 nephrectomy, followed continuous...
Disordered mineral and bone metabolism is a common complication of chronic kidney disease (CKD). Bone biopsy remains the gold standard tool for evaluating renal osteodystrophy (ROD), but it an invasive procedure. Despite growing interest in ability newer biomarkers to discriminate between different forms ROD, data on pre-dialysis patients are scarce.
Abstract Flavonoids are a key class of polyphenols, i.e., phytochemical compounds present in foods and beverages, which have been described as having health benefits preventing several chronic diseases. Estimating flavonoid intake has already conducted countries but yet to be performed Portugal. This study included 5,005 participants aged 3-84 years aimed estimate dietary the Portuguese population, using data from National Food Physical Activity Survey 2015-2016, providing information on...
Myocardial perfusion cardiovascular magnetic resonance (pCMR) using first-pass contrast-enhanced imaging could play an important role in the detection of epicardial and microvascular coronary artery disease. Recently, emergence quantitative pCMR has provided a more reliable observer-independent analysis compared to visual interpretation dynamic images. This review aims cover basics pCMR, from acquisition protocols, its use preclinical clinical studies, image reconstruction motion handling,...
Os ritmos ultradianos são ciclos biológicos menores que 24 horas regulam a secreção pulsátil de hormônios essenciais para homeostase metabólica, incluindo insulina, cortisol e hormônio do crescimento. Esses influenciam diretamente o metabolismo energético, resposta inflamatória regulação da glicose. Sua desregulação tem sido associada doenças endócrinas, como diabetes tipo 2, obesidade distúrbios tireoidianos. Este estudo realizou uma revisão integrativa literatura analisar relação entre...
INTRODUCTION Atypical antipsychotics are essential in managing various psychiatric disorders but associated with significant cardiometabolic side effects, including weight gain, insulin resistance, and dyslipidemia. These adverse effects increase the risk of metabolic syndrome cardiovascular diseases patients undergoing long-term antipsychotic therapy. Understanding underlying mechanisms, such as alterations appetite regulation, glucose, lipid metabolism, is crucial for developing effective...
Abstract Purpose The Planetary Health Diet (PHDiet) proposed by the EAT-Lancet Commission is expected to bear health and environmental benefits. This study assesses adherence PHDiet in Portuguese adults its associations with socioeconomic lifestyle factors. For that, an adapted score was computed, construct validated. Methods Data from National Food Physical Activity Survey 2015–2016 were used for this analysis, covering a representative sample of 3852 two non-consecutive dietary interviews...
To estimate, in a cohort of young Portuguese adults, the environmental impact (greenhouse gas (GHG) emissions, land use, energy used, acidification and potential eutrophication) diet according to adherence Mediterranean Diet (MD).
To adapt four dietary patterns for children and adolescents, study their associations with sustainability (greenhouse-gas emissions-GHGE land use-LU), health (body mass index-BMI) indicators.
Acrylamide exposure, mainly resulting from food cooking and processing, has been associated with a higher risk of health problems, due to genotoxic effects. This study aims estimate acrylamide dietary exposure the Portuguese population its factors. Dietary data collected through 2 non-consecutive 24 hour recalls or diaries representative sample National Food, Nutrition Physical Activity Survey was used (n = 5811; 3-84 years). Occurrence in were obtained EFSA. The margins (MOE) calculated for...
The availability of detailed and high-quality food consumption data is essential for EFSA's risk assessments. In 2014, EFSA published the EU Menu guidance on collecting such in a harmonised way. ERA project aims to give evidence-based recommendations updating menu guidance. Based literature review landscape methods tools available national dietary surveys, lessons learned through an evaluation collected under menu, symposium 'Harmonised Food Consumption Data Collection Europe: Time Reflect...
C. Carvalho, I. Ferreira, S. Gaião, Guimarães, R. Costa, J. Santos, Sampaio, M. Bustorff, G. Oliveira, Pestana. Cerebral coccidioidomycosis after renal transplantation in a non-endemic area.Transpl Infect Dis 2010: 12: 151–154. All rights reserved Abstract: Coccidioidomycosis is fungal infection caused by Coccidioides species endemic to the desert south western United States. In healthy people, manifestations range mainly from asymptomatic mild influenza-like syndrome. immunosuppressed...
Renalase is a recently described enzyme secreted by the kidney into both plasma and urine, where it was suggested to degrade catecholamines contributing blood pressure control. While there controversy regarding relationship between renal function renalase levels, virtually no data in humans on activity as well urine levels activity. We prospectively examined time course of 26 end-stage disease (ESRD) patients receiving cadaver transplant (cadaver recipients [CKR]) before surgery during...
Post-transplant bone disease results from multiple factors, including previous and mineral metabolism disturbances effects transplant-related medications. Bone biopsy remains the gold-standard diagnostic tool.We aimed to prospectively evaluate trabecular cortical by histomorphometry after kidney transplantation. Seven patients, willing perform follow-up biopsy, were included in study. Dual-X-ray absorptiometry trans-iliac performed within first 2 months renal transplantation repeated 2-5...
Bisphenol A (BPA) is an endocrine disruptor used in food contact materials, by the application of polycarbonate plastics and epoxy resins. The main objective this study to compare estimate daily BPA exposure at 13 years age adult Portuguese population, using different methodological approaches, assess associations between sociodemographic characteristics.Cross-sectional data 13-years follow-up from a population-based birth cohort Generation XXI (GXXI) (n = 2804) National Food, Nutrition...
The spectrum of renal osteodystrophy (ROD) in peritoneal dialysis (PD) patients remains to be clarified. Ideal intact parathormone (iPTH) levels range is still not defined. role sclerostin, dickkopf-related protein 1, osteoprotegerin, and receptor activator for nuclear factor κB ligand the diagnosis ROD needs elucidated. In this cross-sectional study, tetracycline double-labeled bone biopsy was performed 49 with histomorphometric analysis according Kidney Disease Improving Global Outcomes...
Background and aims: Bisphenol A (BPA), an endocrine disruptor widely used in food contact materials, has been linked to a worse health profile.This study intends estimate the association between BPA exposure cardiometabolic patterns at adolescence.Methods results: Data from Portuguese population-based birth cohort Generation XXI age of 13 were (n Z 2386 providing 3-day diaries fasting blood samples).BPA was measured 24-h urine subsample 206) then predicted all participants using random...