A5074927567- Adolescent and Pediatric Healthcare
- Childhood Cancer Survivors' Quality of Life
- Child and Adolescent Health
- Hemoglobinopathies and Related Disorders
- Cystic Fibrosis Research Advances
- Mobile Health and mHealth Applications
- Pharmaceutical studies and practices
- Iron Metabolism and Disorders
- Blood groups and transfusion
- Endometriosis Research and Treatment
- Impact of Technology on Adolescents
- Healthcare Systems and Practices
- Child Nutrition and Feeding Issues
- Asthma and respiratory diseases
- Health Systems, Economic Evaluations, Quality of Life
- Pediatric health and respiratory diseases
- Pharmaceutical Practices and Patient Outcomes
- Eosinophilic Esophagitis
- Health Promotion and Cardiovascular Prevention
- School Health and Nursing Education
- Skin and Cellular Biology Research
- Health Literacy and Information Accessibility
- Geriatric Care and Nursing Homes
- Mental Health and Patient Involvement
- Telemedicine and Telehealth Implementation
Inserm
2015-2024
Evaluation et recherche en services et politiques en santé pour les populations vulnérables
2015-2024
Hôpital Robert-Debré
2016-2024
Université Paris Cité
2015-2024
Assistance Publique – Hôpitaux de Paris
2019-2024
Université de Montréal
2024
Sorbonne Paris Cité
2016-2024
Centre Hospitalier de l’Université de Montréal
2024
Centre d'Investigation Clinique Robert Debré
2014-2023
Infection, Anti-microbiens, Modélisation, Evolution
2023
<sec> <title>BACKGROUND</title> Mental health concerns among adolescents and young adults have increased post-pandemic. literacy remains insufficient in this population despite its importance for outcomes. Gaming platforms, central to youth culture, offer potential innovative interventions. </sec> <title>OBJECTIVE</title> To co-design with Minecraft players Twitch streamers, implement, evaluate a gaming-based intervention delivered through broadcasted on promote mental (aged 15-25 years)....
Abstract Introduction Juvenile systemic lupus erythematosus (j-SLE) is a rare chronic autoimmune disease affecting multiple organs. Ranging from minor features, such as headache or mild cognitive impairment, to serious and life-threatening presentations, j-neuropsychiatric SLE (j-NPSLE) therapeutic challenge. Thus, the diagnosis of NPSLE remains difficult, especially in pediatrics, with no specific biomarker yet validated. Objectives To identify central nervous system (CNS) biomarkers...
Objective Juvenile systemic lupus erythematosus (j-SLE) is a rare chronic auto-immune disease involving several organs. Neuropsychiatric (NP) SLE (NPSLE) frequent in j-SLE and associated with increased morbidity/mortality. Although NPSLE classification criteria exist, attributing NP features to remains major challenge. The study objective thoroughly describe j-NPSLE patients assist their diagnosis. Methods This 4-year retrospective monocentric of patients. events were attributed using...
Introduction With advances in surgical and neonatal care, the survival of patients with oesophageal atresia (OA) has improved over time. Whereas a number OA-related conditions (delayed primary anastomosis, anastomotic stricture dysmotility) may have an impact on feeding development although children OA experience several oral aversive events, paediatric disorders (PFD) remain poorly described this population. The aim our study was to describe PFD born OA, using standardised scale. secondary...
The last 20 years have seen many attempts to improve transition adult healthcare for adolescents with chronic disease, but there is currently no established consensus on generic practices. Our goal was identify relevant and pragmatic guidelines practice each step of this process (before, during after transfer), applicable a wide range illnesses health services, via participatory approach involving all the key stakeholders.We conducted interviews literature review elaborate questionnaire use...
The transition from paediatric to adult medicine involves risks of poor patient outcomes and significant losses patients follow up. research aimed analyse the implementation in an initial cohort a new programme care based on case management approach.A longitudinal study approach transition, initiated university hospital France September 2016.Patients with endocrine or metabolic disease diagnosed during childhood transferred were included. includes three steps management: liaising services,...
In children with sickle cell anemia (SCA), early splenic complications can require splenectomy, but the benefit-to-risk ratio and age at which splenectomy may be safely performed remain unclear. To address this question, we analyzed rate of post-splenectomy events in SCA splenectomized between 2000-2018 Robert Debré University Hospital, Paris, France. A total 188 underwent including 101 (11.9%) from our newborn cohort 87 referred to center. Median (Q1-Q3) was 4.1 years (range 2.5-7.3 years),...
Background Acute chest syndromes (ACS) may be associated with upper respiratory tract infections, but the epidemiology of viral and intracellular pathogens in children sickle cell disease (SCD) is not precisely known. The aim this study was to describe SCD presenting fever and/or ACS. Materials methods An observational, prospective, single-centre cohort nested case–control analysis conducted on admitted from October 2016 2017 for ACS paediatric department Robert Debré university hospital,...
Introduction While drug prescription should be based on established recommendations stemming from clinical trials but in pediatrics, many drugs are used without marketing authorization. Consequently often experience and the risk of inappropriate (IP) is high. A tool for detecting IP pediatrics—called POPI (Pediatrics: Omission Prescriptions Inappropriate prescriptions)—has been developed France. However relevance its use at an international level not known. Our aim has to adapt a worldwide...
Multiplex gastrointestinal PCR (GI-PCR) allows fast and simultaneous detection of 22 enteric pathogens (including Campylobacter, Salmonella, Shigella/enteroinvasive Escherichia coli (EIEC), among other bacteria, parasites viruses). However, its impact on the management children with infectious diarrhoea remains unknown.All eligible for stool culture from May to October 2018 were prospectively included in a monocentric study at Robert-Debré University-Hospital.A GI-PCR (BioFire FilmArray) was...
With the purpose of supporting scientific professionals and helping them to better integrate expertise users in their work, a users' relatives' panel (URP) was set up at National Institute for Excellence Health Social Services Quebec (INESSS), Canada social services mental health directorate. URPs are advisory structures that mobilise experiential knowledge people affected by various issues.
Community-acquired and nosocomial lower-respiratory-tract infections in critically ill pediatric patients require early appropriate antibiotic therapy to optimize outcomes. Using blind bronchial samples, we assessed the diagnostic performance of rapid-multiplex polymerase chain reaction (PCR) assay BioFire Pneumonia plus Panel vs. reference standard culturing with antimicrobial susceptibility testing.
Abstract Background A public health student service was set up by the French government in 2018 with aim of increasing awareness primary promotion among 47,000 students medicine and other professions. It is an annual program involving community-based actions on nutrition, physical activity, addiction or sexuality. Our objective to evaluate its implementation at local level different experiences stakeholders. Methods quasi-experimental study using process evaluation performed a Faculty...
Increasing numbers of young people with perinatally acquired HIV are surviving to adulthood. When they come age, leave pediatric services in which were followed and have be transferred the adult health care system. Difficulties adaptation lost follow up after transfer been reported. This transition phase their retention crucial maintaining clinical status these Our study aimed explore how professionals working perceive adapt practices transition.Qualitative interviews conducted 18 social...
International guidelines are published to provide standardized information and fertility preservation (FP) care for adults children. The purpose of the study was conduct a modified Delphi process generating FP BGD. A steering committee identified 42 potential practices Then 114 key stakeholders were asked participate in via two online survey rounds final meeting. Consensus reached 28 items. Among them, rated age-specific concerning risk diminished ovarian reserve after surgery as important...
Peripheral (or small) airway obstruction (PAO) is considered a marker of childhood asthma but the techniques able to directly measure it are rarely used in routine. Usual spirometry and plethysmography can detect certain degree PAO when reduced forced vital capacity (FVC) associated normal expiratory volume 1 s (FEV1 ) FVC ratio, total lung (TLC). The frequency this functional pattern has never been studied different pediatric respiratory conditions. To assess prevalence outcome children...
Introduction Gabapentin is currently used ‘off-label’ in children and adolescents with chronic neuropathic pain, reliable evidence of its effects optimal dosing are lacking. Objectives The GABA-1 trial aims to compare the efficacy safety gabapentin liquid formulation relative tramadol explore pharmacokinetics both drugs treatment chronic, or mixed pain paediatric population. Methods analysis a multicentre, double-blind, double-dummy, randomised, active-controlled, non-inferiority trial....
The majority of hospitalizations patients with sickle cell disease (SCD) are related to painful vaso-occlusive crises (VOCs). Although the pain VOC is classically nociceptive, neuropathic (NP) has also been demonstrated in SCD patients. aim our study specify prevalence NP during VOCs children using a dedicated scale and measure its characteristics. We performed prospective that included hospitalized for an acute VOC. presence was sought DN4 on second fourth days hospitalization. A total 54...