A5061580051- Radiomics and Machine Learning in Medical Imaging
- Medical Imaging Techniques and Applications
- MRI in cancer diagnosis
- Glioma Diagnosis and Treatment
- Advanced MRI Techniques and Applications
- Advanced Neuroimaging Techniques and Applications
- Lung Cancer Diagnosis and Treatment
- Bone and Joint Diseases
- Medical Imaging and Pathology Studies
- Adipose Tissue and Metabolism
- Atomic and Subatomic Physics Research
- Adipokines, Inflammation, and Metabolic Diseases
- Cerebrospinal fluid and hydrocephalus
- Intraperitoneal and Appendiceal Malignancies
- Cancer Diagnosis and Treatment
- Hepatocellular Carcinoma Treatment and Prognosis
- Fetal and Pediatric Neurological Disorders
- Radiopharmaceutical Chemistry and Applications
- Neuroblastoma Research and Treatments
- Exercise and Physiological Responses
- MicroRNA in disease regulation
- Advanced X-ray and CT Imaging
- Neurological Complications and Syndromes
- Lung Cancer Research Studies
- Oral and Maxillofacial Pathology
University of Tübingen
2012-2021
Universitätsklinikum Tübingen
2012-2021
University Children's Hospital Tübingen
2021
Bernstein Center for Computational Neuroscience Tübingen
2020
University Radiology
2015
Siemens (Germany)
2013
Klinik und Poliklinik für Strahlentherapie und Radioonkologie
2012
To compare the performance of magnetic resonance (MR)/positron emission tomography (PET) imaging in staging lung cancer with that PET/computed (CT) as reference standard and to quantification accuracy a new whole-body MR/PET system corresponding PET/CT data sets.Institutional review board approval informed consent were obtained. Ten patients whom bronchial carcinoma was proven or clinically suspected underwent indicated fluorine 18 fluorodeoxyglucose (FDG) and, immediately thereafter, hybrid...
Hybrid PET/MR combines the exceptional molecular sensitivity of PET with high resolution and versatility MR imaging. Simultaneous data acquisition additionally promises use to enhance quality images, for example, by respiratory motion correction. This advantage is especially relevant in thoracic abdominal areas improve visibility small lesions low radiotracer uptake quantification. In this work, applicability performance an MR-based method correction tumor imaging was evaluated phantom...
Hybrid whole-body magnetic resonance/positron emission tomography (MR/PET) systems are a new diagnostic tool enabling the simultaneous acquisition of morphologic and multiple functional data thus allowing for diversified characterization oncological diseases.The aim this study was to investigate image alignment quality MR/PET in patients with pulmonary lesions compare congruency 2 measurements diffusion-weighted imaging (DWI) MR 2-deoxy-[18F] fluoro-2-D-glucose (FDG) uptake PET.A total 15...
To compare anatomic alignment between morphologic and positron emission tomography (PET) images acquired in the abdomen pelvis by using simultaneous magnetic resonance (MR)/PET, PET/computed (CT), retrospective MR/PET fusion to MR PET sequential thoracic different breathing, registration, gating protocols.Informed consent institutional review board approval were obtained. The misalignment 28 abdominal patient datasets was analyzed MR/PET, PET/CT, fusion. In seven datasets, effect of...
Hybrid PET/MR systems have recently entered clinical practice. Thus, the accuracy of MR-based attenuation correction in simultaneously acquired data can now be investigated. We assessed 4 methods lesions within soft tissue, bone, and MR susceptibility artifacts: 2 segmentation-based (SEG1, provided by manufacturer, SEG2, a method with atlas-based artifact correction); an atlas- pattern recognition–based (AT&PR), which also used correction; new combining AT&PR SEG2 (SEG2wBONE)....
The 6th annual meeting to address key issues in positron emission tomography (PET)/magnetic resonance imaging (MRI) was held again Tübingen, Germany, from March 27 29, 2017. Over three days of invited plenary lectures, round table discussions and dialogue board deliberations, participants critically assessed the current state PET/MRI, both clinically as a research tool, attempted chart future directions. addressed use PET/MRI workflows oncology, neurosciences, infection, inflammation chronic...
The objective of this study was to evaluate the frequency and characteristics artifacts in segmentation-based attenuation correction maps (μ-maps) positron emission tomography/magnetic resonance (PET/MR) their impact on PET interpretation standardized uptake value (SUV) quantification normal tissue lesions.The approved by local institutional review board. Attenuation 100 patients with PET/MR preceding PET/computed tomography examination were retrospectively inspected for (tracers:...
Multiparametric PET/MRI with the amino-acid analog O-(2-18F-fluoroethyl)-l-tyrosine (18F-FET) enables simultaneous assessment of molecular, morphologic, and functional brain tumor characteristics. Although it is considered most accurate noninvasive approach in tumors, its relevance for patient management still under debate. Here, we report diagnostic performance 18F-FET impact on clinical a retrospective cohort. Methods: We retrospectively analyzed patients who underwent between 2017 2018....
Purpose To characterize peritoneal carcinomatosis (PC) of different histologically proven primary tumors based on diffusion‐weighted imaging (DWI) and 18 F‐FDG positron emission tomography (PET). Materials Methods Forty‐one patients underwent simultaneous MR/PET after clinically indicated F‐FDG‐PET/CT. For all patients, histology the tumor was obtained. MR protocol comprised anatomical axial DWI. Apparent diffusion coefficient (ADC) maps FDG‐PET were co‐registered for evaluation ADC standard...
To enable fast and flexible high-resolution four-dimensional (4D) MRI of periodic thoracic/abdominal motion for visualization or motion-corrected imaging.We proposed a Cartesian three-dimensional k-space sampling scheme that acquires random combination lines in the ky/kz plane. A partial Fourier-like constraint compacts space to one half k-space. The central line is periodically acquired allow an extraction self-navigated respiration signal used populate multiple breathing positions....
Many radiological signs are known for the diagnosis of idiopathic normal pressure hydrocephalus (iNPH). However, there is little information about these in pre-symptomatic phase. For pathophysiological investigative purposes we conducted a descriptive image analysis study on patients.
Objective: First, to investigate the diagnostic performance of fast T1-weighted sequences for lung nodule evaluation in oncologic magnetic resonance (MR)/positron emission tomography (PET).Second, evaluate influence image acquisition inspiration and expiration breath-hold on performance. Materials Methods:The study was approved by local Institutional Review Board.PET/CT MR/PET 44 cancer patients were evaluated 2 readers.PET/CT included computed (CT) scans (CTin, CTex).MR/PET Dixon sequence...