A5072059396- Retinal Diseases and Treatments
- Retinal Imaging and Analysis
- Retinal and Optic Conditions
- Ophthalmology and Visual Impairment Studies
- Intraocular Surgery and Lenses
- Ocular Diseases and Behçet’s Syndrome
- Corneal surgery and disorders
- Protease and Inhibitor Mechanisms
- Biomedical Research and Pathophysiology
- Fibroblast Growth Factor Research
- Neurological Disorders and Treatments
- Blood Coagulation and Thrombosis Mechanisms
- Retinal and Macular Surgery
- Protein Kinase Regulation and GTPase Signaling
- Advanced biosensing and bioanalysis techniques
- Angiogenesis and VEGF in Cancer
- Ocular Infections and Treatments
- Proteoglycans and glycosaminoglycans research
- Hormonal and reproductive studies
- DNA Repair Mechanisms
- Genetic and Kidney Cyst Diseases
- DNA and Nucleic Acid Chemistry
- Health disparities and outcomes
- Health and Well-being Studies
- Hedgehog Signaling Pathway Studies
Miyata Eye Hospital
2018-2022
Jikei University School of Medicine
2020
MedStar Harbor Hospital
2020
Keio University
2020
Chukyo Hospital
2020
Aichi Medical University
2009-2012
Kobe University
2004
Tumor necrosis factor-alpha (TNF-α) may disrupt the extracellular matrix components comprising blood-retinal barrier (BRB) in patients with posterior uveitis, such as Behçet's disease. We investigated changes mRNA expression levels of metalloproteinases (MMPs) and tissue inhibitors (TIMPs) human BRB cells presence TNF-α vitro examined effect infliximab addition.Cells were cultured or absence TNF-α, TNF-α-exposed treated without infliximab. measured MMP-1, MMP-2, MMP-3, MMP-9, TIMP-1, TIMP-2...
To evaluate the safety and efficacy of a new toric intraocular lens (IOL) with anchor-wing haptics.The IOL haptics (NS60YT, NIDEK Co., Ltd.) was implanted in eligible patients age-related cataracts preoperative corneal astigmatism 1.0 D or greater at university hospital two private hospitals Japan. The following cylinder powers were evaluated: 1.50 (NS60YT3), 2.25 (NS60YT4), 3.00 (NS60YT5) 4.50 (NS60YT7). All assessed out to 12 months postoperatively. primary endpoint visual acuity (VA)...
Abstract Background and Objective We investigated the levels of matrix metalloproteinase‐2 (MMP‐2), which has been implicated in various vitreoretinal diseases, retina after laser photocoagulation (LPC). Materials Methods The time course MMP‐2 expression 2‐day‐old chicken retinas before 6 hours, 12 1 day, 2 days, 4 8 16 32 days LPC was determined by real‐time PCR gelatin zymography. basal level vitreous also measured localization examined immunohistochemistry. mRNA fluorescent situ...
AbstractThe accumulation of DNA damages by environmental stresses is represented the steady state level single strand breaks (SSBs) and double (DSBs). Terminal deoxynucleotidyl transferase (TdT) mediated end labeling suitable in detecting DSBs, but unsuitable for SSBs due to its catalyzing characteristics. However, sensitivity TdT detect may be significantly improved first denaturing strands expose all nicks as potential substrates TdT. By coupling denaturation slot blot southern...
<b><i>Background:</i></b> Differences in the efficacy of bevacizumab, an antivascular endothelial growth factor (VEGF) agent, against retinopathy with neovascularization when injected into vitreous cavity vitrectomized and nonvitrectomized eyes suggests involvement hyaluronan, a major component body. This study aimed to compare affinities hyaluronan for anti-VEGF agents vitro. <b><i>Methods:</i></b> We examined 3 (bevacizumab, pegaptanib...
Purpose: Bardet-Biedl Syndrome (BBS) is an autosomal recessive systemic disorder characterized by retinitis pigmentosa, polydactyly, obesity, intellectual disability, renal impairments, and hypogonadism. The purpose of this study was to determine the ocular characteristics a boy with BBS caused novel homozygous variant in ARL6 (alternative named BBS3 ) gene who had been originally diagnosed punctata albescens. Methods: This observational case study. patient underwent ophthalmological...
Abstract Background: To evaluate the safety and efficacy of a new toric intraocular lens (IOL) with anchor-wing haptics. Methods: The IOL haptics (NS60YT, NIDEK Co., Ltd.) was implanted in eligible patients age-related cataracts preoperative corneal astigmatism 1.0 D or greater at one university hospital two private hospitals Japan. Four cylinder powers were evaluated as follows: 1.50 (NS60YT3), 2.25 (NS60YT4), 3.00 (NS60YT5) 4.50 (NS60YT7). All assessed out to 12 months postoperatively....
Abstract Background: To evaluate the safety and efficacy of a new toric intraocular lens (IOL) with anchor-wing haptics. Methods: The IOL haptics (NS60YT, NIDEK Co., Ltd.) was implanted in eligible patients age-related cataracts preoperative corneal astigmatism 1.0 D or greater at university hospital two private hospitals Japan. following cylinder powers were evaluated: 1.50 (NS60YT3), 2.25 (NS60YT4), 3.00 (NS60YT5) 4.50 (NS60YT7). All assessed out to 12 months postoperatively. primary...