A5085265387- Liver Disease Diagnosis and Treatment
- Hepatocellular Carcinoma Treatment and Prognosis
- Epigenetics and DNA Methylation
- Liver Disease and Transplantation
- Abdominal Trauma and Injuries
- Heat shock proteins research
- Bone fractures and treatments
- thermodynamics and calorimetric analyses
- Preterm Birth and Chorioamnionitis
- Hepatitis B Virus Studies
- RNA modifications and cancer
- Ferroptosis and cancer prognosis
- Pharmacogenetics and Drug Metabolism
- Pregnancy-related medical research
- Cancer, Lipids, and Metabolism
- Abdominal vascular conditions and treatments
- Colorectal Cancer Treatments and Studies
- Physiological and biochemical adaptations
- Hepatitis C virus research
Beijing Ditan Hospital
2014-2023
Capital Medical University
2014-2023
Beijing Obstetrics and Gynecology Hospital
2023
Guangdong Ocean University
2015
Capital University
2014
Background. Early detection appears to be the most effective approach improve overall survival of patients with hepatocellular carcinoma (HCC). We evaluated potential performance plasma SEPT9 methylation (mSEPT9) as a noninvasive biomarker for diagnosis HCC. Methods. A total 373 subjects were included, and group consisted 104 HCC patients, 95 an at-risk disease, 174 healthy controls (HC). The mSEPT9 was determined using methylation-specific fluorescence quantitative PCR. diagnostic assessed...
Heat shock protein 90 (HSP90) is an important molecular chaperone required for proper folding of cellular proteins, and thus, it plays essential role in protecting cells from damage during stress.In this study, HSP90 cDNA designated PmHSP90 was cloned the mantle tissue pearl oyster Pinctada martensii using reverse transcription polymerase chain reaction (RT-PCR) coupled with rapid amplification ends (RACE) approach.PmHSP90 2584 bp length, including open reading frame 2160 bp, which encodes a...
CYP2W1 overexpression has been reported in a variety of human cancers. However, the role hepatocellular carcinoma (HCC) remains unclear. This study was designed to evaluate expression and prognostic significance HCC. Real-time quantitative reverse transcriptase-polymerase chain reaction (qRT-PCR) conducted detect messenger RNA (mRNA) 41 pairs fresh-frozen HCC tissues adjacent noncancerous tissues. In addition, analyzed by immunohistochemistry 133 clinicopathologically characterized cases....
Background To investigate the changes of human leukocyte antigen DR (HLA-DR) and CD38 coexpression subsets on T lymphocytes following interferon (IFN) therapy for those who have chronic hepatitis B (CHB). Methods A prospective cohort CHB patients participated in this study. without IFN treatment (including naïve nucleoside [nucleotide] analogs [NAs]-treated patients) were given pegylated alfa (Peg-IFNα) treatment. Peripheral blood samples taken at baseline, 4 weeks 12-24 Peg-IFNα For entered...
Abstract Objectives Angio-associated migratory cell protein (AAMP) is a that participates in migration and reported to be involved cancer progression. However, the molecular mechanism of AAMP pan-cancer not known. Methods We used multi-omics data, such as TIMER, TCGA, GTEx, CPTAC, HPA, cBioPortal analyze expression, gene alteration pan-cancer. Univariate Cox regression Kaplan–Meier were utilized explore prognostic significance expression level. applied Spearman analysis investigate...
Purpose: This study aimed to evaluate the safety and effectiveness of simultaneous radiofrequency ablation (RFA) combined with laparoscopic splenectomy (Lap-Sp) for patients hepatocellular carcinoma (HCC) complicated cirrhosis hypersplenism.Material methods: Between January 2013 June 2014, 42 primary HCC hypersplenism who underwent RFA Lap-Sp were enrolled at Department General Surgery, Beijing Di Tan Hospital. The median number tumors ablated using was one (range 1–3), sum maximum diameter...
To analyze the non-invasive indexes for predicting esophageal varices (EV) in liver cirrhosis, and to establish a model degree of EV.A total 294 patients with cirrhosis portal hypertension were divided into following groups according EV grade as assessed by endoscopy: non-EV I EV, II III EV. The predictive measures stiffness (LS), platelet (PLT) count, spleen thickness (ST), PLT/ST ratio, vein diameter, flow velocity Child-Pugh score (CPS) univariate analysis multivariate logistic regression...
Objective A randomized controlled trial to compare BiClamp forceps with conventional suture ligation in splenectomy and pericardial devascularization.Methods single-blind (RCT) was conducted on 60 patients hypersplenism esophageal varices who underwent devascularization using either (n =30) or =30).We compared the operation time,intraoperative blood loss,incisional wound infection rate hospital stay between two groups.Results The preoperative demographic data of groups were well matched.The...
Methods: This was a retrospective analysis.Pregnancy outcome, maternal characteristics, past and current medical history, previous history of preterm birth, PAPP-A MoM endocervical length South Asian women who underwent Down's syndrome screening at 11-13 weeks gestation the Apollo Centre for Fetal Medicine, Delhi, India were retrieved.Multivariate logistic regression used to develop model prediction sPTB using combination factors, cervical length.Model predictive performance assessed area...