A5086972634- Pediatric Urology and Nephrology Studies
- Renal and related cancers
- Renal Diseases and Glomerulopathies
- Urological Disorders and Treatments
- Urinary Tract Infections Management
- Urinary Bladder and Prostate Research
- Genetic and Kidney Cyst Diseases
- Cardiac, Anesthesia and Surgical Outcomes
- Vitamin D Research Studies
- Kidney Stones and Urolithiasis Treatments
- Bladder and Urothelial Cancer Treatments
- Genetic Syndromes and Imprinting
- Genomic variations and chromosomal abnormalities
- Regional Development and Management Studies
- Lymphatic Disorders and Treatments
- Infant Nutrition and Health
- Vascular Malformations and Hemangiomas
- Complement system in diseases
- Hedgehog Signaling Pathway Studies
- Blood Pressure and Hypertension Studies
- Coagulation, Bradykinin, Polyphosphates, and Angioedema
- Metabolism and Genetic Disorders
- Urinary and Genital Oncology Studies
- Congenital Anomalies and Fetal Surgery
- Bipolar Disorder and Treatment
University of Split
2011-2024
University of Genoa
2023
Istituto Giannina Gaslini
2023
Morgan Stanley Children's Hospital
2023
Klinički Bolnički Centar Split
2022
Children's Hospital Zagreb
2021
The DiGeorge syndrome, the most common of microdeletion syndromes, affects multiple organs, including heart, nervous system, and kidney. It is caused by deletions on chromosome 22q11.2; genetic driver kidney defects unknown.
Significance Statement Congenital obstructive uropathy (COU) is a prevalent human developmental defect with highly heterogeneous clinical presentations and outcomes. Genetics may refine diagnosis, prognosis, treatment, but the genomic architecture of COU largely unknown. Comprehensive screening study 733 cases three distinct subphenotypes revealed disease etiology in 10.0% them. We detected no significant differences overall diagnostic yield among subphenotypes, characteristic variable...
Background:We assessed prevalence and resistance of uropathogens on antimicrobial agents (AA) from urine cultures (UC) in children hospitalized with urinary tract infections (UTI) at University Hospital Split.Material/Methods:During the 7-year period, only once UTI alone were compared to those repeatedly hospitalized, who received long-term prophylaxis (LTAP), as well associated anomalies system (US).Results:E. coli was most frequent isolate (67.7%) ampicillin by 69.5%,...
Abstract Background Information about renal diseases in children is available from national registries of biopsies. Aim the study was to compare clinical presentation glomerular and tubulointerstitial space with pathohistological diagnosis indicated biopsies pediatric population Croatian region Dalmatia. Methods Out 231 patients suspected , 54 underwent ultrasound-guided biopsy at University Hospital Split. Kidney allograft biopsy, re-biopsy were excluded. The sections examined under light...
Purpose: The aim of this study was to analyze the incidence intrarenal reflux (IRR) among vesicoureteral refluxes (VURs), diagnosed by contrast-enhanced voiding urosonography (ceVUS), define VURs which are positive IRR and their locations in kidney. Materials Methods: Seventy patients with VURs, including 103 uretero-renal units (URUs) grades II–V (37 URUs were excluded because renal anomalies or absence VUR) examined ceVUS due recurrent febrile UTI first accompanied abnormalities on...
Vesicoureteral reflux (VUR) is defined as the urine backflow from urinary bladder to pyelo-caliceal system. In contrast, intrarenal (IRR) of renal calyces into tubulointerstitial space. VURs, particularly those associated with IRR can result in nephropathy when accompanied by tract infection (UTI). The prevalence patients diagnosed VUR 1-11% using voiding cystourethrography (VCUG), while 11.9-61% applying contrast-enhanced urosonography (ceVUS). presence VCUG often correlates parenchymal...
AIMTo investigate correlation of perinatal risk factors in newborns with gastrointestinal perforation (GIP).February 27, 2017|Volume 9|Issue 2| WJGS|www.wjgnet.comPrgomet S et al .Perinatal according to gestational age.Ponderal index was not differing between infants GIP and control subjects.In anemia more frequently found than group. CONCLUSIONGIP is mostly disease birth weight below 10 th percentile age.GIP occurs often anemia.
To describe the parenchymal defects in kidneys with intrarenal reflux (IRR) diagnosed using contrast-enhanced voiding urosonography (ceVUS) and 99mTc-DMSA scintigraphy (DMSA scan).A group of 186 uretero-renal units (URUs) was analyzed ceVUS DMSA scans: 47 without vesicoureteral (VUR) (group A) 139 VURs, comprising 73 VURs B), 66 IRR C). included non-dilating (grades I-II), mildly (grade III), IV-V) grades. The changes were a scan.The median age for VUR diagnosis 16.5 months girls, 8.5 boys...
BACKGROUND:Renal parenchymal damage and scarring usually is associated with urinary tract infection (UTI), whereas the impact of vesicoureteral reflux (VUR) on kidneys unclear. We aimed to compare all grades VUR (grades Io–V) those without by using direct radionuclide cystography, voiding cystourethrography, findings from 99mTc-DMSA scintigraphy (DMSA scan). MATERIAL AND METHODS:The present analysis included 253 renal ureteral units (RUU) 129 children recurrent UTI a single febrile abnormal...
Introduction Bardet-Biedl syndrome (BBS) is a rare genetic caused by mutation in one of 26 different genes responsible for normal structure and/or function primary cilia. The characterized multiorgan involvement with gradual onset occurrence clinical signs and symptoms resulting great phenotypic variability what more important, often difficulties establishing the timely diagnosis. Case report We case family three members BBS very mutation, compound heterozygosity BB12 gene. Even though all...
BACKGROUND:Thrombotic thrombocytopenic purpura (TTP) in children is a rare life-threatening syndrome, characterized by microangiopathic hemolytic anemia, thrombocytopenia with renal dysfunction, neurologic symptoms, and fever. TTP usually caused deficient activity of von Willebrand factor cleaving protease (ADAMTS13), due to either gene mutations or acquired via anti-ADAMTS13 autoantibodies. It can be triggered bone marrow solid organ transplantation, cardiothoracic-, abdominal-, orthopedic...
Lymphoscintigraphy is not considered as a first line diagnostic procedure in abdominal or thoracic lymphorrhea of various origin. We report patient with lymphangiectasia whom posttraumatic was diagnosed by lymphoscintigraphy only after third attempt when we applied pushups exercise the aim to raise venous pressure and thus provoke lymph backflow ductus thoracicus enteric lymphytics. Lymphorrhea clearly visible colon ascendens transversum on 9h planar scintigram. propose tailored individual...
Prikazom ove bolesnice naglašavamo kako udruživanje nefrotskog sindroma, mikrocefalije i cerebelarne atrofi je u ranoj životnojdobi može biti rijetko opisivani Galloway-Mowatov sindrom (GMS). GMS obično prati kongenitalni ili rani dojenački nefrotskisindrom te progresivno gubljenje djetetovih neuroloških funkcija, katkad uz postojanje hijatus hernije. Bolesnici imaju lošu prognozui umiru prvim godinama života. Iako se drži da prenosi autosomno recesivno, odgovorni gen geni još je/su...
Prikazom ove bolesnice naglašavamo kako udruživanje nefrotskog sindroma, mikrocefalije i cerebelarne atrofi je u ranoj životnojdobi može biti rijetko opisivani Galloway-Mowatov sindrom (GMS). GMS obično prati kongenitalni ili rani dojenački nefrotskisindrom te progresivno gubljenje djetetovih neuroloških funkcija, katkad uz postojanje hijatus hernije. Bolesnici imaju lošu prognozui umiru prvim godinama života. Iako se drži da prenosi autosomno recesivno, odgovorni gen geni još je/su...