A5040400409- Nanoplatforms for cancer theranostics
- Tea Polyphenols and Effects
- Polysaccharides and Plant Cell Walls
- Bacteriophages and microbial interactions
- Luminescence and Fluorescent Materials
- Marine and coastal ecosystems
- Tuberculosis Research and Epidemiology
- Gas Sensing Nanomaterials and Sensors
- Advanced biosensing and bioanalysis techniques
- Food Quality and Safety Studies
- Photoacoustic and Ultrasonic Imaging
- Enzyme Production and Characterization
- Analytical Chemistry and Sensors
- Plant Reproductive Biology
- Fuel Cells and Related Materials
- Supramolecular Self-Assembly in Materials
- Studies on Chitinases and Chitosanases
- Photodynamic Therapy Research Studies
- Water Quality Monitoring and Analysis
- Tryptophan and brain disorders
- Viral gastroenteritis research and epidemiology
- Hydraulic and Pneumatic Systems
- Remote-Sensing Image Classification
- Gold and Silver Nanoparticles Synthesis and Applications
- Nanoparticle-Based Drug Delivery
Hunan Agricultural University
2007-2025
Shanghai Pulmonary Hospital
2009-2025
Tongji University
2009-2025
Shandong Jianzhu University
2025
Ministry of Agriculture and Rural Affairs
2024-2025
Hunan University
2025
Guiyang Medical University
2025
Columbia University
2024
Henan University
2014-2024
Beijing University of Chemical Technology
2024
Abstract Extensive recent progress has been made on the design and applications of organic photothermal agents for biomedical because their excellent biocompatibility comparing with inorganic materials. One major hurdle further development is rarity high‐performance materials in second near‐infrared (NIR‐II) window, which allows deep tissue penetration causes minimized side effects. Up till now, there have few reported NIR‐II‐active conversion efficiencies are relatively low. Herein, optical...
An increasing amount of evidence suggests that the gut microbiota composition and structure contribute to pathophysiology metabolic syndrome (MS), which has been put forward as a new target in treatment diet-induced MS. In this work, we aimed investigate effects Fuzhuan brick tea polysaccharides (FBTPS) on MS dysbiosis high-fat diet (HFD) fed mice further whether its attenuation is related modulation microbiota. The results showed FBTPS intervention could significantly attenuate HFD-induced...
Adaptation to hypoxia is a major challenge for the survival of Mycobacterium tuberculosis (Mtb) in vivo. Interferon (IFN)-γ-producing CD8
We evaluated the effects of yellow tea extract on relieving constipation induced by loperamide and changes gut microbiota based 16S rRNA gene sequencing.
Rucheng Baimaocha (Camellia pubescens) black tea (RCBT) exhibits floral and sweet attributes with a unique minty-like aroma, distinguishing it from traditional other innovative teas. However, its key odorants remain unknown. In this study, gas chromatography-olfactometry (GC-O) combined aroma extraction dilution analysis detected 26 aroma-active compounds (ACCs), of which 20 ACCs were quantified as RCBT infusion. addition, recombination models well simulated the overall characteristics...
Abstract Based on the excitation fault mechanism model of marine synchronous generators, this paper builds a generator and simulates output waveforms voltage, current, speed under different operating conditions. With help simulation data, generators is analyzed, mathematical morphological features in are extracted using neural networks. A diagnosis for based ResNet-18 residual network established. Finally, test data input into to obtain F1 score model, which has been verified meet accuracy...
T cells are crucial in controlling Mycobacterium tuberculosis infection and disease progression. Nevertheless, the specific functions changes of lymphocyte subsets retreatment remain poorly understand. The study aims to identify immunoprotective effect TCM tuberculosis. We collected venous blood from participants assessed using flow cytometry. Univariate analysis regression model were used evaluate key In study, while frequencies CD4 CD8 similar between primary patients, patients exhibited a...
The fluorescent quantum dots (QDs) delivered small interfering RNAs (siRNAs) targeting β-secretase (BACE1) to achieve high transfection efficiency of siRNAs and reduction β-amyloid (Aβ) in nerve cells. CdSe/ZnS QDs with the conjugation amino-polyethylene glycol (PEG) were synthesized. Negatively charged electrostatically adsorbed surface develop QD-PEG/siRNA nanoplexes. QD-PEG/siRNAs nanoplexes significantly promote siRNA, from non-packaged widely distributed cell bodies processes...
Abstract Lung cancer, especially lung adenocarcinoma, is one of the most common neoplasms worldwide. However, mechanisms underlying its initiation, development, and metastasis are still poorly understood. Destrin (DSTN) a member ADF/cofilin family. Its detailed biological function remains unknown, although it reported that DSTN involved in cytoskeleton remodeling regulation actin filament turnover. Recent evidence has shown high expression cofilin-1 associated with invasion poor prognosis...
Abstract The systemic use of pharmaceutical drugs for cancer patients is a compromise between desirable therapy and side effects because the intrinsic shortage organ‐specific drug. Design construction drug to achieve delivery thus desperately desirable. We herein regulate perylene skeleton effect organ‐specificity present an example lung‐specific distribution on basis bay‐twisted PDIC‐NC. further demonstrate that PDIC‐NC can target into mitochondria act as cellular respiration inhibitor,...
Countries have formulated different transformation plans due to differences in resource endowments, energy strategies, and technological levels. Among them, the Chinese government has proposed continuing increase proportion of renewable generation field power supply, especially wind power, achieve transition. Northern China is rich resources, demand for heating autumn winter high, providing favorable conditions promoting from perspective supply demand. However, costs benefits each...
Tuberculosis (TB) remains a major health problem affecting millions of people worldwide. One-third the world's population is infected with Mycobacterium tuberculosis, etiologic agent TB. A simple and rapid method to diagnose TB urgently needed be developed. The procedure systematic evolution ligands by exponential enrichment (SELEX) in which single-stranded oligonucleotides (called aptamers) are selected from wide variety sequences, based on their interaction target molecule. Aptamers have...
Autolysis of Coprinopsis cinerea fruiting bodies affects its commercial value. In this study, a mutant C. that exhibits pileus expansion without autolysis was obtained using ultraviolet mutagenesis. This suggests and involve different enzymes or proteins. Among the detected hydrolytic enzymes, only β-1,3-glucanase activity increased with pilei in wild-type strain, but increase abolished mutant. β-1,3-glucanases plays major role autolysis. Although there are 43 possible β-1,3-glucoside...
Two perylene conductometric sensors with excellent selectivity and low detection limit towards ethylenediamine vapor have been developed by ionic self-assembly.
We purified a chitinase from pilei extractions of Coprinopsis cinerea fruiting bodies by ammonium sulfate precipitation and CM Sepharose cation exchange chromatography. MALDI-TOF/TOF MS analysis characterized this as putative class V chitinase, ChiB1. ChiB1 hydrolyzed colloidal chitin chitosan, whereas it did not hydrolyze powder. cleaved only pNP-(GlcNAc)2, rather than pNP-GlcNAc or pNP-(Glc-NAc)3, to release nitrophenol. preferably progressively released (GlcNAc)2 (GlcNAc)6 digested two...
A putative class III endochitinase (ChiIII) was reported previously to be expressed dominantly in fruiting bodies of Coprinopsis cinerea, and its expression levels increased with the maturation bodies. This paper further reports that ChiIII is a novel chitinase exo- endoactivities. When substrate (GlcNAc)3-5, exhibited exoactivity, releasing GlcNAc processively from reducing end (GlcNAc)3-5; when (GlcNAc)6-7, activity shifted an endoacting enzyme, randomly splitting chitin oligosaccharides...
This work presents an efficient method of accessing <bold>DPP-SO</bold> that not only possess excellent anti-tumour property but also regulates the photothermal performance DPP-conjugated polymers by changing heteroatom in molecular skeleton.
The supramolecular helicity and gas response of perylene dyes can be well modulated by chalcogen atoms in the core.
Abstract High‐performance photothermal theranostics is urgently desired for cancer therapy because of their good controllability and noninvasive features. The relatively low conversion efficiency still at the drawbacks absence efficient extraneous carriers. Herein, a carrier‐free nanomedicine developed to in vivo self‐deliver organic agents phototheranostics. By facile self‐assembly strategy, near‐infrared (NIR)‐absorbing conjugated oligomer IDIC‐4F fabricated into nanoparticle (DCF‐P),...