Li Tuo

ORCID: 0000-0002-3005-9287
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About
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Research Areas
  • Genomics and Phylogenetic Studies
  • Microbial Natural Products and Biosynthesis
  • Microbial Community Ecology and Physiology
  • Microbial Metabolism and Applications
  • Bacteriophages and microbial interactions
  • Plant Disease Resistance and Genetics
  • Actinomycetales infections and treatment
  • Plant-Microbe Interactions and Immunity
  • Plant Pathogens and Fungal Diseases
  • Landfill Environmental Impact Studies
  • Biofuel production and bioconversion
  • Aquaculture disease management and microbiota
  • Metabolomics and Mass Spectrometry Studies
  • Plant Pathogenic Bacteria Studies
  • Fungal and yeast genetics research
  • S100 Proteins and Annexins
  • RNA modifications and cancer
  • Geotechnical Engineering and Soil Stabilization
  • Insect symbiosis and bacterial influences
  • Traumatic Brain Injury and Neurovascular Disturbances
  • Mycotoxins in Agriculture and Food
  • Selenium in Biological Systems
  • Enzyme Production and Characterization
  • Legume Nitrogen Fixing Symbiosis
  • Plant biochemistry and biosynthesis

Zunyi Medical University
2016-2025

Graz University of Technology
2023-2025

Nanjing Agricultural University
2017-2024

Beijing National Laboratory for Molecular Sciences
2018-2024

Chinese Academy of Sciences
2018-2024

University of Chinese Academy of Sciences
2018-2024

Zhejiang Sci-Tech University
2022-2024

Soil and Fertilizer Institute of Hunan Province
2024

Yulin University
2022-2023

Austrian Centre of Industrial Biotechnology (Austria)
2023

Exploiting a pure culture strategy to investigate the composition of human gut microbiota, two novel anaerobes, designated strains AF52-21T and CM04-06T, were isolated from faeces healthy Chinese donors characterized using polyphasic approach. The observed be gram-negative, non-motile, rod-shaped. Both grew optimally at 37 °C pH 7.0. Phylogenetic analysis based on 16S rRNA gene sequences revealed that clustered with species genus Faecalibacterium most closely related prausnitzii ATCC 27768T...

10.1038/s41598-021-90786-3 article EN cc-by Scientific Reports 2021-05-31

A novel actinomycete, designated strain CA15-2(T), was isolated from a soil sample collected the rhizosphere of tamarisk in Lop Nor region, Xinjiang, China, and characterized by using polyphasic taxonomic approach. Optimal growth occurred at 37 °C pH 7.5-8.0 with 5% (w/v) NaCl. Strain CA15-2(T) formed white to pale-yellow branched substrate mycelium without fragmentation sparse aerial wavelike curves. Whole-cell hydrolysates isolate contained meso-diaminopimelic acid as diagnostic diamino...

10.1099/ijs.0.055160-0 article EN INTERNATIONAL JOURNAL OF SYSTEMATIC AND EVOLUTIONARY MICROBIOLOGY 2014-10-21

Traumatic brain injury often causes poor outcomes and has few established treatments. Neuroinflammation ferroptosis hinder therapeutic progress in this domain. Annexin A5 (A5) anticoagulant, anti-apoptotic anti-inflammatory bioactivities. However, its protective effects on traumatic remain unclear. Thus, we explored whether inhibiting neuroinflammation using could ameliorate injury. We injected recombinant (50 µg/kg) the tail vein of mice 30 min after fluid percussion then assessed modified...

10.1016/j.intimp.2022.109619 article EN cc-by-nc-nd International Immunopharmacology 2022-12-21

A Gram-stain-positive, aerobic and non-motile actinobacterium, designated strain MR15.9 T , was isolated from sediment collected a mangrove ecosystem in Semarang city, Indonesia. Strain grew at 4–37 °C (optimum 30 °C), pH 6.0–11.0 7.0–8.0), with 0–10% (w/v) NaCl 0–3%). The genome of 3.67 Mbp 71.7 mol% G+C content. Phylogenetic analysis based on 16S rRNA gene sequence directed that formed well-supported clade Tersicoccus solisilvae CGMCC 1.15480 phoenicis 1P05MA shared the highest similarity...

10.1099/ijsem.0.006669 article EN INTERNATIONAL JOURNAL OF SYSTEMATIC AND EVOLUTIONARY MICROBIOLOGY 2025-02-03

The structural motif of hetero-di-C-glycosyl compound is prominent in plant polyphenol natural products and involves two different glycosyl residues (e.g., β-d-glucosyl, β-d-xylosyl) attached to carbons the same phenolic ring. Polyphenol hetero-di-C-glycosides attract attention as specialized ingredients herbal medicines their tailored synthesis by enzymatic C-glycosylation promising overcome limitations low availability expand molecular diversity new-to-nature glycoside structures. However,...

10.1002/bit.28948 article EN cc-by Biotechnology and Bioengineering 2025-02-07

A rod- or coccus-shaped, non-spore-forming actinobacterium, designated strain SC8A-24(T), was isolated from a soil sample collected the rhizosphere of Alhagi sparsifolia on southern edge Taklimakan desert, Xinjiang, China, and examined by polyphasic approach to clarify its taxonomic position. This actinobacterium Gram-staining-positive aerobic. Substrate aerial mycelia were not observed, no diffusible pigments observed media tested. Strain SC8A-24(T) grew optimally without NaCl at 28-30 °C...

10.1099/ijs.0.000147 article EN INTERNATIONAL JOURNAL OF SYSTEMATIC AND EVOLUTIONARY MICROBIOLOGY 2015-02-26

Acinetobacter baumannii (A. baumannii) has emerged as one of the most troublesome pathogens in health care institutions. A. can cause a wide range diseases humans, including pneumonia and septicemia. Phage therapy drawn great interest from medical researchers potential way to control infections by antibiotic-resistant . Using pandrug-resistant clinical isolate AB ZY 9 an indicator, we isolated lytic phage Abp9 hospital sewage. belongs myoviridae family shows wider host 12%. contains linear...

10.3389/fmicb.2020.506068 article EN cc-by Frontiers in Microbiology 2020-09-08

Trichoderma spp. is a cosmopolitan group of soil fungi which plays remarkable role in stimulating plant growth after interacting with roots and has good application prospects intensive agriculture. In this study, rice straw amino acids improved the population guizhouense NJAU4742 under solid-state fermentation helped us develop new type organic fertilizer. The effects biological fertilizer were evaluated peppers (Capsicum annuum L.) for two seasons sandy mountain soils. first season, yields...

10.3390/microorganisms8091296 article EN cc-by Microorganisms 2020-08-25

The cardiac transcription factor Tbx20 has a critical role in the proper morphogenetic development of vertebrate heart, and its misregulation been implicated human congenital heart disease. Although it is established that exerts function embryonic through positive negative regulation distinct gene programs, unclear how mediates transcriptional target genes. Here, using combinatorial proteomic bioinformatic approach, we present first characterization protein complexes. We have systematically...

10.1021/pr400818c article EN Journal of Proteome Research 2013-09-12

Close relationships between ticks and microbial communities are important for tick fitness pathogen colonization transmission. Haemaphysalis longicornis, distributed widely in China, can carry transmit various pathogens pose serious damages to public health economics. However, little is known about the broader array of symbionts H. longicornis under natural conditions. In present study, we investigated composition bacterial associated with evaluated putative symbionts. The eubacterial 16S...

10.1186/1756-3305-6-310 article EN cc-by Parasites & Vectors 2013-10-28

The combination of microdialysis and mass spectrometry (MS) provides the potential for rapidly monitoring diverse metabolites in vivo. Unfortunately, high concentration salt biological microdialysates hindered sensitive online detection these small molecular compounds. In this study, we synthesized Co-incorporated mesoporous carbon material (Co-NC) developed a Co-NC-assisted laser desorption/ionization (LDI) ion source as an interface vivo coupled with MS direct analysis microdialysates....

10.1021/acs.analchem.0c00227 article EN Analytical Chemistry 2020-03-17

A novel endophytic actinobacterium, designated strain 8BXZ-J1T, was isolated from surface-sterilized branches of Thespesia populnea collected Beilun Estuary Mangrove Forest National Nature Reserve in Guangxi, China, and examined by a polyphasic approach to determine its taxonomic position. Cells the isolate were Gram-stain-positive, aerobic, non-spore-forming, non-motile short rod-shaped. Phylogenetic analysis based on 16S rRNA gene sequences suggested that 8BXZ-J1T belonged genus...

10.1099/ijsem.0.002297 article EN INTERNATIONAL JOURNAL OF SYSTEMATIC AND EVOLUTIONARY MICROBIOLOGY 2017-09-18

Abstract Docosahexaenoic acid (DHA) is verified to have neuroprotective effects on traumatic brain injury (TBI) rats by activating Nrf2 signaling pathway, but the role of NOX 2 in this effect has not been illuminated. So study explored TBI models treated with DHA, aiming complete mechanism DHA. rat were constructed or without DHA treatment, and H O -induced hippocampal neurons pretreated alone combination inhibitor brusatol. The neurological function, cognitive ability, cerebral edema degree...

10.1007/s11064-020-03078-z article EN cc-by Neurochemical Research 2020-07-16

Abstract Glycosylated derivatives of natural product polyphenols display a spectrum biological activities, rendering them critical for both nutritional and pharmacological applications. Their enzymatic synthesis by glycosyltransferases is frequently constrained the limited repertoire characterized enzyme-catalyzed transformations. Here, we explore glycosylation capabilities substrate preferences newly identified plant uridine diphosphate (UDP)-dependent (UGTs) within UGT72 UGT84 families,...

10.1038/s42004-024-01231-1 article EN cc-by Communications Chemistry 2024-06-28

A Gram-positive, aerobic, coccus-shaped, non-spore-forming actinobacterium, designated strain M1HQ-2T, was isolated from a surface-sterilized bark of Scutellaria baicalensis Georgi collected Guizhou, China and tested using polyphasic approach to determine its taxonomic position. Strain M1HQ-2T grew at 4-37 °C (optimum, 30 °C), pH 5.0-11.0 (pH 8.0) in the presence 0-15 % (w/v) NaCl (1-3 %). Substrate mycelia aerial were not formed, diffusible pigments observed on any media tested....

10.1099/ijsem.0.003032 article EN INTERNATIONAL JOURNAL OF SYSTEMATIC AND EVOLUTIONARY MICROBIOLOGY 2018-09-19

An alkaliphilic and moderately halophilic actinobacterium, designated strain GP10-3(T), was isolated from Populus euphratica collected the southern edge of Taklimakan desert, Xinjiang, China. Cells this were Gram-stain-positive, non-motile non-spore-forming short rods. Strain GP10-3(T) grew optimally at 37 °C on LB agar media in presence 5-10% (w/v) NaCl pH 9.0. The menaquinones MK-7, MK-8 MK-9. major fatty acids (>10%) anteiso-C17 : 0, anteiso-C15 0 iso-C16 0. peptidoglycan type variation...

10.1099/ijs.0.000123 article EN INTERNATIONAL JOURNAL OF SYSTEMATIC AND EVOLUTIONARY MICROBIOLOGY 2015-02-26

A Gram-stain-positive, aerobic, coccus-shaped, non-spore-forming actinobacterium, designated strain 2Q3S-4-2T, was isolated from the surface-sterilized bark of Kandelia candel, collected Cotai Ecological Zones in Macao, PR China. It tested using a polyphasic approach to determine its taxonomic position. Strain 2Q3S-4-2T grew optimally without NaCl at 28-30 °C and pH 7.0. Substrate mycelia aerial were not formed no diffusible pigments observed on media tested. Phylogenetic analysis, based 16S...

10.1099/ijsem.0.000923 article EN INTERNATIONAL JOURNAL OF SYSTEMATIC AND EVOLUTIONARY MICROBIOLOGY 2016-01-26

A Gram-negative, motile, aerobic and coccoid rod-shaped bacterium, designated strain 2T4P-2-4T, was isolated from a piece of surface-sterilized bark Aegiceras corniculatum collected Cotai Ecological Zones in Macao, China, tested by polyphasic approach to clarify its taxonomic position. Strain 2T4P-2-4T grew optimally without NaCl at 28–30 °C, pH 7.0–8.0. The 16S rRNA gene sequence had the highest similarity (96.2 %) Aureimonas rubiginis CC-CFT034T. Phylogenetic analysis showed that grouped...

10.1099/ijsem.0.002046 article EN INTERNATIONAL JOURNAL OF SYSTEMATIC AND EVOLUTIONARY MICROBIOLOGY 2017-08-01

A novel endophytic actinobacterium, designated strain IP6SC6T, was isolated from surface-sterilized bark of Bruguiera gymnorhiza collected Zhanjiang Mangrove Forest National Nature Reserve in Guangdong, China. Cells IP6SC6T were Gram-stain-positive, aerobic, non-spore-forming, non-motile rods. Strain grew at 20-42 °C (optimum, 37 °C), pH 6.0-9.0 7.0) and the presence 0-8 % (w/v) NaCl 0-2 %). Chemotaxonomic analyses showed that isolate possessed meso-diaminopimelic acid as diamino...

10.1099/ijsem.0.000842 article EN INTERNATIONAL JOURNAL OF SYSTEMATIC AND EVOLUTIONARY MICROBIOLOGY 2015-12-13

A Gram-stain-positive, aerobic, coccoid, non-motile, non-spore-forming bacterium, designated strain S3Af-1T, was isolated from surface-sterilized bark of Bruguiera sexangula collected Dongzhaigang National Nature Reserve in Hainan, China, and examined using a polyphasic approach to clarify its taxonomic position. This bacterium did not produce substrate mycelia or aerial hyphae, no diffusible pigments were observed on the media tested. Strain S3Af-1T grew optimally without NaCl, at 28-30 °C...

10.1099/ijsem.0.000779 article EN INTERNATIONAL JOURNAL OF SYSTEMATIC AND EVOLUTIONARY MICROBIOLOGY 2015-11-19
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