- Traumatic Brain Injury and Neurovascular Disturbances
- Trauma and Emergency Care Studies
- Traumatic Brain Injury Research
- Cardiac Arrest and Resuscitation
- Cerebrospinal fluid and hydrocephalus
- Neurosurgical Procedures and Complications
- Glioma Diagnosis and Treatment
- Meningioma and schwannoma management
- Head and Neck Surgical Oncology
- Sepsis Diagnosis and Treatment
- Neurobiology of Language and Bilingualism
- Spinal Dysraphism and Malformations
- Neurological disorders and treatments
- Advanced Neuroimaging Techniques and Applications
- Pituitary Gland Disorders and Treatments
- Spinal Fractures and Fixation Techniques
- Spine and Intervertebral Disc Pathology
- Adrenal and Paraganglionic Tumors
- Parkinson's Disease Mechanisms and Treatments
- Acute Ischemic Stroke Management
- Intracerebral and Subarachnoid Hemorrhage Research
- Radiation Dose and Imaging
- Botulinum Toxin and Related Neurological Disorders
- Brain Metastases and Treatment
- Functional Brain Connectivity Studies
BioCruces Health research Institute
2020-2025
University of the Basque Country
1995-2025
Hospital de Cruces
2012-2025
University of Groningen
2022
University Hospital Heidelberg
2021
Heidelberg University
2021
Charité - Universitätsmedizin Berlin
2020
Humboldt-Universität zu Berlin
2020
Freie Universität Berlin
2020
The incidence of Traumatic Brain Injury (TBI) is increasingly common in older adults aged ≥65 years, forming a growing public health problem. However, are underrepresented TBI research. Therefore, we aimed to provide an overview health-care utilization, and six-month outcomes after their determinants who sustained TBI.We used data from the prospective multi-center Collaborative European NeuroTrauma Effectiveness Research (CENTER-TBI) study. In-hospital post-hospital care utilization were...
In this article we investigate the changes observed in scales that quantify quality of life (PDQ-39) patients have already completed 1 and 2 years bilateral subthalamic stimulation (DBS-STN). Fourteen were evaluated year after DBS-STN; evaluation was repeated on 11 them, surgery. All them suffered from Parkinson's disease with a 14.3 (+/-5.7) history motor complications. Patients selected according to CAPSIT criteria. implanted electrodes nucleus. The parameters applied UPDRS II, III,...
Delayed radiation-induced complications after stereotactic radiosurgery (SRS) for arteriovenous malformations (AVM) have scarcely been described in the literature, and their incidence, pathophysiology, treatment remain unclear. Additionally, literature regarding these is confusing. The authors present a well-documented case report describing late complications, adding evidence to possible common pathophysiological mechanism underlying them, illustrating an effective modality when they occur....
<title>Abstract</title> Are an individual’s first (L1) and second (L2) languages represented in shared or distinct brain territories? Using intraoperative electrical stimulation mapping (ESM) two Basque-Spanish bilinguals with non-growing lesions—thus avoiding confounding effects of adaptive plasticity—this study identified language representations within the left temporal lobe. Stimulation posterior anterior superior gyri induced language-selective aphasias, whereas mid-temporal region...
CSF leaks due to anterior skull base defects, particularly those involving the posterior wall of frontal sinus, are complex and often require surgical intervention. The endoscopic transorbital approach provides a direct, minimally invasive method with enhanced access improved working angles. authors present video 41-year-old female spontaneous leak sinus encephalocele who underwent repair. This effectively controlled defect, resulting in resolution no recurrence at 1-year follow-up. is...
Although most pituitary neoplasms are benign, some grow rapidly, spreading to extrasellar tissues. Definition of these 'giant' adenomas (PAs) is not clear. In order clarify this question, we studied all macroadenomas operated in our hospital during the last 20 years, differentiating those with diameter > or = 3 cm (n 43) and attempting identify their typical features prognosis. The reason for consultation was local 58.3% giant PAs, hormonal 22.9% tumour recurrence 16.7%. Surgery performed...
OBJECTIVE Recently, the endoscopic superior eyelid transorbital approach (SETA) has emerged as a potential alternative to access cavernous sinus (CS). Several previous studies have attempted quantitatively compare traditional open anterolateral skull base approaches with exposure; however, these comparisons been limited area of exposure provided by bone opening and trajectory, fail account for main avenues subsequent requisite surgical maneuvers. The authors frontotemporal-orbitozygomatic...
Picture naming tasks are currently the gold standard for identifying and preserving language-related areas during awake brain surgery. With multilingual populations increasing worldwide, patients frequently need to be tested in more than one language. There is still no reliable testing instrument, as available batteries have been developed specific languages. Heterogeneity selection criteria stimuli leads differences, example, size, color, image quality, even names associated with pictures,...
We report a retrospective observational study of 185 cases with spontaneous supratentorial intracerebral haemorrhage, in which, by univariate and multivariate analysis, the main clinical CT findings influencing patient outcome were studied. Forty (22%) patients died 77 (41%) remained very disabled state. Using logistic regression analysis we found that volume haematoma, its deep location, surgical treatment preictal status relation to activities daily living (ADL) independent factors for...
Abstract Recent evidence suggests that damage to the language network triggers its functional reorganization. Yet, spectro‐temporal fingerprints of this plastic rearrangement and relation anatomical changes is less well understood. Here, we combined magnetoencephalographic recordings with a proxy measure white matter investigate oscillatory activity supporting plasticity structural reshaping. First, cortical dynamics were acquired in group healthy controls during object action naming....
To understand the pathogenesis of glioblastoma multiforme (GBM) we used high-resolution comparative genomic hybridization arrays and gene expression microarrays to identify DNA copy number alterations changes in comparable sets GBM samples. Gains were detected at chromosomes 1, 2, 7, 9, 12, 19, 20 losses 6, 10. Gene analyses identified specific genes overexpressed mapping amplified chromosomal regions. Among these found involved angiogenesis, extracellular matrix remodeling several...
Abstract Research on the neural imprint of dual-language experience, crucial for understanding how brain processes dominant and non-dominant languages, remains inconclusive. Conflicting evidence suggests either similarity or distinction in processing, with implications bilingual patients tumors. Preserving functions after surgery requires considering pre-diagnosis neuroplastic changes. Here, we combine univariate multivariate fMRI methodologies to test a group healthy Spanish-Basque...