Ernest van Veen
A5089108782- Traumatic Brain Injury and Neurovascular Disturbances
- Traumatic Brain Injury Research
- Trauma and Emergency Care Studies
- Cardiac Arrest and Resuscitation
- Palliative Care and End-of-Life Issues
- Sepsis Diagnosis and Treatment
- COVID-19 and healthcare impacts
- Cardiac, Anesthesia and Surgical Outcomes
- Neurosurgical Procedures and Complications
- Cerebrospinal fluid and hydrocephalus
- Clinical practice guidelines implementation
- Health Systems, Economic Evaluations, Quality of Life
- Radiation Dose and Imaging
- Spinal Fractures and Fixation Techniques
- S100 Proteins and Annexins
- Autopsy Techniques and Outcomes
- Frailty in Older Adults
- Hip and Femur Fractures
- Ethics in Clinical Research
- Healthcare Decision-Making and Restraints
- Anesthesia and Neurotoxicity Research
- Trauma, Hemostasis, Coagulopathy, Resuscitation
- Organ Donation and Transplantation
- Machine Learning in Healthcare
- Emergency and Acute Care Studies
Erasmus MC
2018-2025
University of Cambridge
2022
Addenbrooke's Hospital
2022
University of Groningen
2022
Erasmus University Rotterdam
2020-2022
University of Antwerp
2022
Antwerp University Hospital
2022
Karolinska Institutet
2022
University of Maryland, College Park
2021
University of York
2021
In patients with severe brain injury, withdrawal of life-sustaining measures (WLSM) is common in intensive care units (ICU). WLSM constitutes a dilemma: instituting too early could result death despite the possibility an acceptable functional outcome, whereas delaying unnecessarily burden patients, families, clinicians, and hospital resources. We aimed to describe occurrence timing WLSM, factors associated European ICUs traumatic injury (TBI). The CENTER-TBI Study prospective multi-center...
The incidence of Traumatic Brain Injury (TBI) is increasingly common in older adults aged ≥65 years, forming a growing public health problem. However, are underrepresented TBI research. Therefore, we aimed to provide an overview health-care utilization, and six-month outcomes after their determinants who sustained TBI.We used data from the prospective multi-center Collaborative European NeuroTrauma Effectiveness Research (CENTER-TBI) study. In-hospital post-hospital care utilization were...
Background Following traumatic brain injury (TBI), the clinical focus is often on disability. However, patients’ perceptions of well-being can be discordant with their disability level, referred to as ‘disability paradox’. We aimed examine relationship between and health-related quality life (HRQoL) following TBI, while taking variation in personal, injury-related environment factors into account. Methods used data from Collaborative European NeuroTrauma Effectiveness Research Traumatic...
Increased intracranial pressure (ICP) is one of the most important modifiable and immediate threats to critically ill patients suffering from traumatic brain injury (TBI). Two hyperosmolar agents (HOAs), mannitol hypertonic saline (HTS), are routinely used in clinical practice treat increased ICP. We aimed assess whether a preference for mannitol, HTS, or their combined use translated into differences outcome. The Collaborative European NeuroTrauma Effectiveness Research Traumatic Brain...
Traumatic brain injury (TBI) poses a huge public health and societal problem worldwide. Uncertainty exists on how care system treatment approaches for TBI worked in China may differ from those Europe. Better knowledge this is important to facilitate interpretation of findings reported by Chinese researchers inform opportunities collaborative studies. We aimed investigate concordance variations between European neurotrauma centers. Investigators 52 centers 68 Europe involved the Collaborative...
We aimed to study variation regarding specific end-of-life (EoL) practices in the intensive care unit (ICU) traumatic brain injury (TBI) patients. Respondents from 67 hospitals participating The Collaborative European NeuroTrauma Effectiveness Research Traumatic Brain Injury (CENTER-TBI) completed several questionnaires on management of TBI In 60% centers, ≤50% all patients with severe neurological damage dying ICU, die after withdrawal life-sustaining measures (LSM). decision...
We aimed to investigate the extent of agreement on practices around brain death and postmortem organ donation. Investigators from 67 Collaborative European NeuroTrauma Effectiveness Research in Traumatic Brain Injury (CENTER-TBI) study centers completed several questionnaires (response rate: 99%). Regarding death, we found clinical evaluation (prerequisites neurological assessment) for determination (BDD) 100% centers. However, ancillary tests were required BDD 64% nondonor patients was...
Coronavirus disease 2019 has put unprecedented pressure on healthcare systems worldwide, leading to a reduction of the available capacity. Our objective was develop decision model estimate impact postponing semielective surgical procedures health, support prioritization care from utilitarian perspective.A cohort state-transition developed and applied 43 nonpediatric commonly performed in academic hospitals. Scenarios delaying surgery 2 weeks were compared with up 1 year no at all. Model...
Abstract Background The European Union (EU) aims to optimize patient protection and efficiency of health-care research by harmonizing procedures across Member States. Nonetheless, further improvements are required increase multicenter efficiency. We investigated IRB in a large prospective study on traumatic brain injury (TBI), aiming inform stimulate initiatives improve Methods reviewed relevant documents regarding submission approval from neurotrauma centers participating the Collaborative...
Sedation, administration of mannitol or hypertonic saline, mild hyperventilation, moderate hypothermia and high-dose barbiturate therapy are all strategies in the treatment intracranial hypertension traumatic brain injury (TBI). Intracranial pressure (ICP) >20 mmHg not responding to conservative caries a bad prognosis, mortality exceeding 80%. A final option refractory might be decompressive (hemi)craniectomy.
ABSTRACT Introduction Older age is associated with worse outcome after traumatic brain injury (TBI). Whether this association entirely driven by frailty, or clinicians’ reluctance to give specific treatments older patients unclear. Therefore, we aimed confirm the between and outcome, assess received high-intensity treatment (HIT). Methods We included TBI aged 16 from CENTER-TBI study. The HIT, (the Glasgow Outcome Scale Extended (GOSE) at 6 months), was analyzed using multivariable ordinal...
Abstract Background COVID-19 has put unprecedented pressure on healthcare systems worldwide, leading to a reduction of the available capacity. Our objective was develop decision model that supports prioritization care from utilitarian perspective, which is minimize population health loss. Methods A cohort state-transition developed and applied 43 semi-elective non-paediatric surgeries commonly performed in academic hospitals. Scenarios delaying surgery two weeks were compared with up one...
Abstract Background The European Union (EU) aims to optimize patient protection and efficiency of health-care research by harmonizing procedures across Member States. Nonetheless, further improvements are required increase multicenter efficiency. We investigated IRB in a large prospective study on traumatic brain injury (TBI), aiming inform stimulate initiatives improve efficiency.Methods reviewed relevant documents regarding submission approval from neurotrauma centers participating the...
Abstract Background:The European Union (EU) aims to optimize patient protection and efficiency of health-care research by harmonizing procedures across Member States. Nonetheless, further improvements are required increase multicenter efficiency. We investigated IRB in a large prospective study on traumatic brain injury (TBI), aiming inform stimulate initiatives improve Methods: reviewed relevant documents regarding submission approval from neurotrauma centers participating the Collaborative...
Previously, we published a decision model to guide prioritization of semielective surgeries in times operation room scarcity across disciplines from utilitarian perspective.1Gravesteijn B. Krijkamp E. Busschbach J. et al.Minimizing population health loss scarce surgical capacity during the coronavirus disease 2019 crisis and beyond: modeling study.Value Health. 2021; 24: 648-657Abstract Full Text PDF PubMed Scopus (5) Google Scholar The estimates expected because delay surgery for these...
Abstract Introduction: Increased intracranial pressure (ICP) is one of the most important modifiable and immediate threats to critically ill patients suffering from traumatic brain injury (TBI). Two hyperosmolar agents (HOA), mannitol hypertonic saline (HTS) are routinely used in clinical practice treat increased ICP. We aimed assess whether a preference for mannitol, HTS or their combined use translated into differences (functional) outcome. Methods: The CENTER-TBI Study prospective...