A5102843192- Asthma and respiratory diseases
- Chronic Obstructive Pulmonary Disease (COPD) Research
- Extracellular vesicles in disease
- Airway Management and Intubation Techniques
- Pneumonia and Respiratory Infections
- Tracheal and airway disorders
- Cholangiocarcinoma and Gallbladder Cancer Studies
- Esophageal and GI Pathology
- Respiratory viral infections research
- Chromatography in Natural Products
- RNA modifications and cancer
- Voice and Speech Disorders
- IL-33, ST2, and ILC Pathways
- Acute Myeloid Leukemia Research
- Immune cells in cancer
- Inflammatory Biomarkers in Disease Prognosis
- Respiratory Support and Mechanisms
- Adipose Tissue and Metabolism
- Algal biology and biofuel production
- Phytochemistry and Biological Activities
- Inhalation and Respiratory Drug Delivery
- Machine Learning in Healthcare
- Proteins in Food Systems
- S100 Proteins and Annexins
- Cancer-related gene regulation
Shanghai Jiao Tong University
2013-2024
Dalian University of Technology
2023
Shanghai Children's Medical Center
2022-2023
Second Affiliated Hospital of Zhejiang University
2022-2023
Dalian University
2023
This is the first and largest prospective, multicenter, active, population-based surveillance study of epidemiology Mycoplasma pneumoniae among outpatient children with mild respiratory tract infections (RTIs) during COVID-19 pandemic. Nationwide measures like strict face mask wearing restrictions on population movement implemented to prevent spread might also effectively M. .
The distribution of allergens has geographic characteristics. Local epidemiological data provides evidence-based strategies for the prevention and management allergic diseases. Age sex differences may exist in prevalence sensitivity to various allergens. We investigated common children Shanghai, southeastern China. 39,926 1 month 18 years age diagnosed with diseases were tested presence serum-specific Immunoglobulins E (sIgE) 17 this region, using a reversed enzyme allergosorbent test....
Chlorella oil nanoliposomes (CO-NLP) were synthesized through ultrasonic injection with ethanol, and their physicochemical properties hypolipidemic efficacy systematically investigated. The results revealed that the mean particle size of CO-NLP was 86.90 nm encapsulation efficiency (EE) 92.84%. Storage conditions at 4 °C conducive to stability CO-NLP, maintaining an EE approximately 90% even after 10 days storage. release profile adhered more closely first-order kinetic model during in vitro...
Angelica keiskei contains a variety of bioactive compounds including chalcone, coumarin, and phytochemicals, endowing it with pharmacological effects such as lipid-lowering activity, antitumor liver protection, nerve protection. This study aims to the hypoglycemic hypolipidemic flavonoid-rich extract from (FEAK) in an effort exploit new applications FEAK increase its commercial value. In this paper, flavonoid were extracted using 50% ethanol, contents analyzed by UPLC-MS/MS. Then, activities...
The microRNAs (miRNAs) in cancer-derived exosomes have the ability to change tumor microenvironment. This study aims investigate role of miRNA pancreatic cancer (PC).Based on analysis PC-derived and healthy by bioinformatics quantitative real-time PCR validation, miR-3960 was identified be most significantly different miRNA, TFAP2A proved as its potential target gene. Besides, were isolated from PANC-1 cells identified. After that, treated with or transfected mimics si-TFAP2A, effect...
(1) Background: The relationship between obesity and asthma is still uncertain. This study aimed to investigate the effect of overweight/obesity on pulmonary function patients with new-onset pediatric explore possible causative factors related concomitant asthma. (2) Methods: Patients aged 5 17 years old newly diagnosed mild moderate were recruited from June 2018 May 2019, a respiratory clinic in Shanghai, China. Participants categorized into three groups: normal weight, overweight, obese A...
Central airway stenosis (CAS) in infants is characterized by dysphonia, dyspnea, cyanosis, repeated apnea, and infection. This case series study aimed to evaluate the safety efficacy of holmium laser, cryoablation budesonide inhalation treating with severe CAS.This retrospective reviewed medical records data 28 CAS who underwent laser treatment and/or balloon dilatation therapy at Shanghai Children's Medical Center between June 2014 May 2020. Outcomes were defined as success when stenotic...
This study aimed to establish a pediatric lower respiratory tract infections (PLRTIs) database based on the structured electronic medical records (SEMRs), provide brief overview and usage process of SEMRs database.All information is recorded by clinical system developed Eureka Systems Company. A plugin software was used set properties items SEMR. Children with (LRTIs) who were admitted department medicine our hospital from May 2020 included. PostgreSQL 13.1 construct PLRTIs database.Seven...
e16153 Background: Biliary tract cancers are clinically heterogenous with poor prognosis. The traditional location-based classification of biliary is helpful while the boundary between subtypes still ambiguous. We hereby analyzed comprehensive molecular characterizations across different types among and further to identify similarities differences help individualized treatment. Methods: Tumor tissue samples from 219 Chinese cancer patients were profiled by next generation sequencing a 539...
In this paper, the main content is to investigate which experimental methods are needed in study of case mechanism aortic dissection and how analyze results by analyzing methods. The researchers used RNA sequencing, ChIP-Seq technology, transcription factor prediction, dual-luciferase reporter assay, immunohistochemical staining, immunofluorescent matrix metalloproteinases (MMP) activity western blot statistical analysis. quantitative RT-PCR, In-Gel zymography, oxidant measurement...
Abstract Objective : To establish the predicted value of pulmonary function determined by Impulse Oscillometry (IOS) in children (4~17 years old) China. Methods A total 6270 healthy aged 4 to 17 Shanghai were included. The Master Screen IOS device (Jaeger Co, Germany) was used detect respiratory impedance (Zrs), resonant frequency (Fres)), viscosity resistance (Rrs) and elastic (Xrs) at various oscillation frequencies, indexes above analyzed. stepwise multivariate regression equation related...