A5009038954- Nasal Surgery and Airway Studies
- Plant Molecular Biology Research
- Plant Stress Responses and Tolerance
- Synthesis and Biological Activity
- Facial Rejuvenation and Surgery Techniques
- Reconstructive Facial Surgery Techniques
- Cleft Lip and Palate Research
- Asthma and respiratory diseases
- Obstructive Sleep Apnea Research
- Photosynthetic Processes and Mechanisms
- Sinusitis and nasal conditions
- Anesthesia and Pain Management
- Dermatologic Treatments and Research
- Chemical synthesis and alkaloids
- Olfactory and Sensory Function Studies
- Respiratory viral infections research
- Pneumonia and Respiratory Infections
- Carbohydrate Chemistry and Synthesis
- Health and Lifestyle Studies
- Food Allergy and Anaphylaxis Research
- Allergic Rhinitis and Sensitization
- Plant biochemistry and biosynthesis
- Body Contouring and Surgery
- Spine and Intervertebral Disc Pathology
- Microbial Natural Products and Biosynthesis
Peking University
2022-2024
Peking University Third Hospital
2022-2024
Shanghai Children's Medical Center
2012-2024
Shanghai Jiao Tong University
2018-2024
Chinese Academy of Medical Sciences & Peking Union Medical College
2011-2023
Northeast Forestry University
2019-2023
Peking Union Medical College Hospital
2011-2023
Anhui Normal University
2018
Southern Medical University
2014
General Hospital of Guangzhou Military Command
2014
This is the first and largest prospective, multicenter, active, population-based surveillance study of epidemiology Mycoplasma pneumoniae among outpatient children with mild respiratory tract infections (RTIs) during COVID-19 pandemic. Nationwide measures like strict face mask wearing restrictions on population movement implemented to prevent spread might also effectively M. .
Multifaceted non-pharmaceutical interventions during the COVID-19 pandemic have not only reduced transmission of SARS-CoV2, but had an effect on prevalence other pathogens. This retrospective study aimed to compare and analyze changes respiratory pathogens in hospitalized children with community-acquired pneumonia.From January 2019 December 2020, pneumonia were selected from Department Respiratory Medicine, Shanghai Children's Medical Center. On first day hospitalization, sputum, throat...
The salt overly sensitive (SOS) signal transduction pathway is one of the most highly studied tolerance pathways in plants. However, molecular mechanism stress response Tamarix hispida has remained largely unclear. In this study, five SOS genes ( ThSOS1 – ThSOS5 ) from T. were cloned and characterized. expression levels ThSOS significantly changed after NaCl, PEG 6000 , abscisic acid (ABA) treatment at least organ. Notably, ThSOS3 was downregulated 6 h under stress. To further analyze...
The asymmetric total synthesis of (-)-saframycin A, a natural antitumor product the tetrahydroisoquinoline antibiotics family, has been accomplished by employing L-tyrosine as starting chiral building block in 24 steps for longest linear sequence an overall yield 9.7%. key involve stereoselective intermolecular and intramolecular Pictet-Spengler reactions, which induced correct stereochemistry at C-1 C-11, respectively. selective protection-deprotection protocol amino group two-step...
This was a cross-sectional survey to investigate the relationship of age, parent education, sleep duration, physical activity, and dietary habits with overweight or obesity in school-age children Shanghai.The gathered information from 13,001 grades 1 through 5 (age 6 10 years) among 26 elementary schools 7 districts. Activity level evaluated using International Children's Leisure Activities Study Survey Questionnaire (CLASS-C). The definitions normal, overweight, obese were adjusted for each...
Objective: Lung auscultation plays an important role in the diagnosis of pulmonary diseases children. The objective this study was to evaluate use artificial intelligence (AI) algorithm for detection breath sounds a real clinical environment among children with diseases. Method: auscultations were collected respiratory department Shanghai Children's Medical Center (SCMC) by using electronic stethoscope. discrimination results all chest locations respect gold standard (GS) established 2...
Abstract Background Peroxiredoxins (Prxs) are a large family of antioxidant enzymes that respond to biotic and abiotic stress by decomposing reactive oxygen species (ROS). In this study, the tolerance function Th2CysPrx gene was further analysed. It lays foundation for studies on salt molecular mechanism T. hispida improved via transgenic plants. Results The results tobacco showed higher seed germination rates, root lengths, fresh weight under than wild-type tobacco. Simultaneously,...
Glycine-rich RNA-binding proteins (GRPs) have been implicated in the responses of plants to environmental stresses, but function GRP genes involved salt stress and underlying mechanism remain unclear. In this study, we identified BpGRP1 (glycine-rich protein), a Betula platyphylla gene that is induced under stress. The physiological molecular tolerance were investigated both BpGRP1-overexpressing suppressed conditions. BpGRF3 (growth-regulating factor 3) was as regulatory upstream BpGRP1. We...
Abstract Background Excessive accumulation of long‐chain fatty acids in the pancreatic islets is associated with beta cell dysfunction and ultimately contributes to pathogenesis type 2 diabetes. It has been well proved that death‐inducing DFF45‐like effector b (Cideb) involved apoptosis lipid metabolism. However, expression function Cideb endocrine pancreas remain be investigated. Methods By using reverse transcript polymerase chain reaction, immunohistochemistry Western blot, we observed...
Objective: To compare the effectiveness of an intercostal nerve block after costal cartilage harvest when a multimodal cocktail or ropivacaine plus patient-controlled analgesia is used, as measured by visual analog scale (VAS) scores, rescue analgesic consumption, and related complications. Materials Methods: Eligible patients who underwent were equally randomized to receive (multimodal group) (ropivacaine group). Results: Of 112 assessed, 12 (10.7%) excluded 100 (89.3%) enrolled assigned...
Abstract Ulcer in radiation‐damaged tissue is a dilemma with limited treatment strategies. The study aimed to evaluate the safety and efficacy of regional flaps for patients post‐radiation ulcers through 10‐year experience. A retrospective consecutive at single institute from 2012 2022 was conducted. Reconstruction included complete excision irradiated coverage well‐vascularised tissue, including local flaps, free flaps. Study outcomes complications, reoperation rates, overall flap success...
Abstract The microRNAs, which are small RNAs of 18–25 nt in length, act as key regulatory factors posttranscriptional gene expression during plant growth and development. However, little is known about their roles response to stressful environments birch (Betula platyphylla). Here, we characterized further explored miRNAs from osmotic- salt-stressed birch. Our analysis revealed a total 190 microRNA (miRNA) sequences, were classified into 180 conserved 10 predicted novel based on sequence...