Xinling Zhang

ORCID: 0000-0003-3783-0465
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About
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Research Areas
  • Pelvic floor disorders treatments
  • CRISPR and Genetic Engineering
  • Metal-Organic Frameworks: Synthesis and Applications
  • Galectins and Cancer Biology
  • Glycosylation and Glycoproteins Research
  • Viral Infectious Diseases and Gene Expression in Insects
  • Plant Virus Research Studies
  • Reconstructive Surgery and Microvascular Techniques
  • Ultrasound and Hyperthermia Applications
  • Wound Healing and Treatments
  • Covalent Organic Framework Applications
  • Pregnancy-related medical research
  • Carbohydrate Chemistry and Synthesis
  • Anorectal Disease Treatments and Outcomes
  • Gynecological conditions and treatments
  • Spine and Intervertebral Disc Pathology
  • Magnesium Oxide Properties and Applications
  • Advancements in Battery Materials
  • Advanced Battery Materials and Technologies
  • Postharvest Quality and Shelf Life Management
  • Diverticular Disease and Complications
  • Advanced Nanomaterials in Catalysis
  • Textile materials and evaluations
  • MicroRNA in disease regulation
  • Maternal and Perinatal Health Interventions

Zhejiang Shuren University
2022-2025

Changzhou University
2025

Hunan Normal University
2025

Hunan Provincial People's Hospital
2025

Third Affiliated Hospital of Zhengzhou University
2024-2025

Northeast Agricultural University
2025

Third Affiliated Hospital of Sun Yat-sen University
2012-2024

Sun Yat-sen University
2013-2024

China University of Mining and Technology
2020-2024

Inner Mongolia Agricultural University
2023-2024

10.1016/j.bbadis.2011.01.009 article EN Biochimica et Biophysica Acta (BBA) - Molecular Basis of Disease 2011-01-20

Abstract: The fabrication and initial applications of nanobubbles (NBs) have shown promising results in recent years. A small particle size is a basic requirement for ultrasound contrast-enhanced agents that penetrate tumor blood vessel pores to allow targeted imaging therapy. However, the nanoscale particles used has disadvantage weakening ability clinical diagnostic ultrasound. In this work, we fabricated lipid NBs agent evaluated its passive targeting vivo. showed were (436.8 ± 5.7 nm),...

10.2147/ijn.s28830 article EN cc-by-nc International Journal of Nanomedicine 2012-02-01

Constructed through relatively weak noncovalent forces, the stability of organic supramolecular materials has shown to be a challenge. Herein, designing linear conjugated polymer is proposed creating chain connected via bridging covalent bonds in one direction and retaining π-stacked aromatic columns its orthogonal direction. Specifically, three analogs polymers tuning core covalently linked moiety (bridging group) within building block monomer are prepared. Cooperatively supported by strong...

10.1002/adma.202300655 article EN Advanced Materials 2023-03-31

Abstract SIRT1 is the most evolutionarily conserved mammalian sirtuin, and it plays a vital role in regulation of metabolism, stress responses, genome stability, ageing. As sensor, deacetylase activity significantly increased during stresses, but molecular mechanisms are not yet fully clear. Here, we show that dynamically modified with O-GlcNAc at Ser 549 its carboxy-terminal region, which directly increases both vitro vivo. The O-GlcNAcylation elevated genotoxic, oxidative, metabolic...

10.1038/s41467-017-01654-6 article EN cc-by Nature Communications 2017-11-08

Objectives Statins and calcium channel blockers have been proven beneficial toward improvement of endothelial function. The aim this study was to compare the effect combination therapy statin blocker with solo treatment in patients cardiac syndrome X. Methods results Sixty-eight X were divided randomly into three groups: fluvastatin (40 mg/day, n=23), diltiazem (90 n=22), mg/day) n=23). At end 90 days, coronary flow reserve improved groups (fluvastatin-treated group: 23.2%; diltiazem-treated...

10.1097/mca.0000000000000054 article EN Coronary Artery Disease 2013-11-20

10.1016/j.colsurfa.2022.128421 article EN Colloids and Surfaces A Physicochemical and Engineering Aspects 2022-01-26

The fabrication of photocatalysts with preferable degradation ability is critical to purify wastewater. MIL-53(Fe), as a representative Fe-based metal–organic framework (Fe-MOF), has been widely used in photocatalysis due its excellent intrinsic characteristics. However, the inadequate electron number MIL-53(Fe) restricted photodegradation organic pollutants. Herein, desirable, energy-efficient, and environmentally friendly MIL-53(Fe)/Sn3O4 nanosheet were first constructed by solvothermal...

10.1021/acsanm.3c00400 article EN ACS Applied Nano Materials 2023-05-26

Abstract To investigate whether human umbilical cord mesenchymal stem cell‐derived exosomes combined with gelatin methacryloyl (GelMA) hydrogel are beneficial in promoting healing of laser‐injured skin wounds mice. Supernatants cultured cells (HUC‐MSCs) were collected to obtain MSC‐derived (HUC‐MSCs‐Exos), which GelMA complex treat a mouse fractional laser injury model. The study was divided into PBS group, EX (HUC‐MSCs‐Exos) GEL (GelMA hydrogel) group and EX+GEL (HUC‐MSCs‐Exos group. each...

10.1111/iwj.14295 article EN cc-by-nc-nd International Wound Journal 2023-07-10

Systematic and in-depth explorations of the effects side-chain modulation on molecular assembly, optoelectronic properties, photocatalytic properties supramolecular systems, as well kinetics charge separation migration in these are rare. In this study, a novel photocatalyst with an alkoxy side chain (S-EPDI) was successfully developed through subtle design short linear alkoxyl chains, affording phenol degradation efficiency approximately four times that counterpart alkyl (S-APDI). Notably,...

10.1016/j.greenca.2024.05.006 article EN cc-by-nc-nd Green Carbon 2024-07-01

In this study, we compared the effects of various doses dexmedetomidine on incidence atrial fibrillation following cardiac surgery in adults. 224 adult patients who underwent elective were randomly assigned to two groups. The DEX0.5 group received a continuous infusion at rate 0.5 μg·kg⁻1·h⁻1, while DEX1 it 1 μg·kg⁻1·h⁻1 during induction anesthesia, which was maintained for 24 hours. primary outcome fibrillation, secondary outcomes included other tachyarrhythmias, bradycardia, hypotension,...

10.1097/fjc.0000000000001674 article EN Journal of Cardiovascular Pharmacology 2025-01-23

Background: Intrahepatic cholangiocarcinoma (ICC) is a poor prognosis of malignant cancer with high lymph node metastasis and resistance to systemic therapies. Recent studies suggested that the involvement IL-8 could promote ICC through epithelial–mesenchymal transition while ICC-ALDH1A1 subtype clarified by multi-omics study. The correlation between ALDH1A1 in remains elusive. This study aims further explore roles regulatory mechanisms ICC. Methods: We analyzed expression patients cells....

10.1097/hc9.0000000000000664 article EN cc-by-nc-nd Hepatology Communications 2025-02-26

ACS (1-aminocyclopropane-1-carboxylic acid synthase) is a member of the aminotransferase superfamily and pyridoxal phosphate-dependent enzyme. also rate-limiting enzyme for biosynthesis ethylene has been linked with plant development, growth, stress responses. However, information on genes in soybean genome limited. In this study, we identified through phylogenetic trees conserved motifs analyzed their cis-acting elements, subcellular localization, expression patterns. Twenty-two members...

10.3390/ijms26062526 article EN International Journal of Molecular Sciences 2025-03-12
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