A5101699778- interferon and immune responses
- Neurological Disease Mechanisms and Treatments
- Neuroinflammation and Neurodegeneration Mechanisms
- Plant Gene Expression Analysis
- Cancer, Lipids, and Metabolism
- Plant biochemistry and biosynthesis
- Phytochemicals and Antioxidant Activities
- Invertebrate Immune Response Mechanisms
- RNA modifications and cancer
- Ferroptosis and cancer prognosis
- Muscle Physiology and Disorders
- Inflammasome and immune disorders
- Plant Disease Resistance and Genetics
- Traditional Chinese Medicine Analysis
- Aquaculture disease management and microbiota
- Marine Invertebrate Physiology and Ecology
- Chromosomal and Genetic Variations
- Extracellular vesicles in disease
- Composting and Vermicomposting Techniques
- Cancer Cells and Metastasis
- Axon Guidance and Neuronal Signaling
- Genetics and Physical Performance
- Muscle metabolism and nutrition
- Biomarkers in Disease Mechanisms
- Galectins and Cancer Biology
Institute of Apiculture Research
2024-2025
Chinese Academy of Agricultural Sciences
2024-2025
Shenyang Pharmaceutical University
2021-2024
Shanghai University of Traditional Chinese Medicine
2020-2023
Weifang Medical University
2021-2022
Tianjin Medical University Cancer Institute and Hospital
2019-2021
Shanghai Academy of Agricultural Sciences
2008-2021
Shandong Normal University
2015-2016
Baylor College of Medicine
1988-1991
Anthocyanins are secondary metabolites that contribute to red, blue, and purple colors in plants affected by light, but the effects of low light on physiological responses pak-choi plant leaves still unclear. In this study, seedlings were exposed shading with white gauze black a phytotron. The terms photosynthetic properties, carbohydrate metabolism, antioxidant enzyme activity, anthocyanin biosynthetic relative chlorophyll content measured. results showed b, intracellular CO2 content,...
Abstract Tumor metastasis induced by drug resistance is a major challenge in successful cancer treatment. Nevertheless, the mechanisms underlying pro-invasive and metastatic ability of remain elusive. Exosome-mediated intercellular communications between cells stromal tumor microenvironment are required for initiation progression. Recent reports have shown that also promote aggression. However, little attention has been regarded on this aspect. Herein, we demonstrated drug-resistant...
In this study, the full‐length complementary (c)DNA of interleukin‐1 receptor‐associated kinase 1 gene ( irak1 ) was cloned from common carp Cyprinus carpio . The complete open reading frame contained 2109 bp encoding a protein 702 amino acid residues that comprised death domain, ProST region, serine–threonine‐specific catalytic domain and C‐terminal domain. amino‐acid sequence C. Irak1 shared homology with grass Ctenopharyngodon idellus (84·5%). phylogenetic tree IRAKs separated...
In this study, the full‐length complementary (c) DNA of common carp Cyprinus carpio melanoma differentiation‐associated gene 5 ( mda5 ) was cloned. The complete open reading frame C. contained 2982 bp and encodes 993 amino acids. deduced acids six functional domains: two caspase activation recruitment domains CARD ), a conserved restriction domain bacterial type III enzyme ResIII DExD /H box‐containing DEXDc helicase super family C‐terminal HELICc regulatory RD ). expressed in all tested...
Clubroot is one of the most serious diseases affecting Brassicaceae plants worldwide. However, there no effective control method for clubroot. Salicylic acid (SA) a plant hormone that plays critical role in defense. In our study, we found disease severity clubroot-sensitive cultivar pakchoi, Xinxiaqing, was reduced with 0.6mM exogenous SA after infection P . brassicae To investigate mechanism SA-reduced against clubroot, then analyzed growth, alteration antioxidant enzyme system, and related...
Lespedeza bicolor Turcz. (L. bicolor) honey, a monofloral has garnered increased attention due to its origin in the L. plant. A previous study shown that honey can ameliorate inflammation. In this study, we aimed investigate effects of extract and biomarker (Trifolin) on DSS-induced ulcerative colitis (UC). Our results demonstrated Trifolin significantly expression levels tight junction cytokines Claudin-1 ZO-1. Additionally, they decreased pro-inflammatory factors TNF-α IL-6 enhanced...
Chronic exposure of differentiated avian skeletal muscle cells in culture to the phorbol ester, 12-O-tetradecanoyl phorbol-13-acetate (PMA), results selective disassembly sarcomeric structures and loss muscle-specific contractile proteins, leaving cytoskeletal their associated proteins intact. We demonstrate here that these morphological biochemical changes are accompanied by dramatic decreases level mRNAs encode proteins. measured effects PMA on transcriptional activity mRNA stability four...
Specific DNA fragments complementary to the 3' untranslated regions of beta-, alpha-cardiac, and alpha-skeletal actin mRNAs were used as in situ hybridization probes examine differential expression distribution these primary myogenic cultures. We demonstrated that prefusion bipolar-shaped cells derived from day 3 dissociated embryonic somites equivalent myoblasts 11-12 pectoral tissue with respect alpha-cardiac gene. Fibroblasts present muscle cultures not labeled by gene probe. Since...
Microcalcification is a very important diagnostic information in breast cancer. The purpose of this study was to determine the relationship clinicopathological features and prognosis cancer with microcalcification detect biomarkers related possible mechanisms microcalcifications.All 529 subjects microcalcifications were selected from patients who had been examined using mammography. control group did not have detectable microcalcifications, matched ratio 1:3. factors, progression-free...
ATP-binding cassette (ABC) transporter family are major contributors to the drug resistance establishment of breast cancer cells. Breast resistant protein (BCRP), one ABC transporters, has long been recognized as a pump that effluxes therapeutic drugs against concentration gradient. However, recent studies suggest biological function BCRP is not limited in its activity. Herein, role proliferation and survival drug-resistant cells was investigated. We found efflux epirubicin express multiple...
Hypopharyngeal squamous cell carcinoma (HSCC) is highly malignant and extremely aggressive, making it one of the worst prognoses among all kinds head neck (HNSCC); therefore, gaining insight into molecular mechanisms HSCC profound significance. In current manuscript, we revealed elevated expression long noncoding RNA (lncRNA) LEF1-AS1 in HNSCC which was associated with poor prognosis by bioinformatic analysis. Moreover, noticed that dramatically accelerated proliferation, migration,...
Myosin superfamily, a large and diverse family of molecular motors important for cell motility migration, has been illustrated to play contradictory roles during the development several kinds tumors. However, function prognostic values MYOs in head neck squamous carcinoma (HNSCC) still remain largely unknown. In current manuscript, expression levels clinical data HNSCC were investigated by online databases, including Oncomine, GEPIA, GEO, TCGA, HPA, UALCAN, Kaplan-Meier plotter, CancerSEA;...
DL‑3‑n‑butylphthalide (NBP) is commonly used to treat ischemic strokes due its antioxidative and anti‑inflammatory effects. The present study aimed examine the protective effects of NBP on myocardial ischemia‑reperfusion injury (MIRI) by establishing a MIRI model in H9c2 cells. Cell viability assay using Counting Kit‑8, lactate dehydrogenase (LDH) cytotoxicity lipid peroxidation malondialdehyde (MDA) content were assessed detect cell activity, degree oxidative stress reaction. Reverse...
Temperature is a main environmental factor that affects anthocyanin biosynthesis and accumulation in purple pakchoi (Brassica campestris ssp. Chinensis Makino.). Purple one of the most popular vegetables with high content China. Recently, we found color cultivar, "ziyi", deepened after 10-day low temperature(5°C, LT) treatment increased compared to plants 20°C (normal temperature, NT, control) treatment. Contractly, treated heat temperature (35°C, HT) became lighter...
Small gourd ( Lagenaria siceraria var . microcarpa (Naud.) Hara), a cultivar of family, is an important medicinal and ornamental plants. However, there are few studies on its chloroplast (cp) genome. In this study, we characterized complete genome with high throughput sequencing. The circular cp determined to be 157, 121 bp in length, long sing-copy small separated by pair of inverted repeat regions. A total 132 genes were annotated, including 86 protein-coding...