A5063305363- Bioactive natural compounds
- Nitric Oxide and Endothelin Effects
- Bladder and Urothelial Cancer Treatments
- Advanced X-ray and CT Imaging
- Cardiac Ischemia and Reperfusion
- Nanoplatforms for cancer theranostics
- Neuroscience and Neuropharmacology Research
- Drug Transport and Resistance Mechanisms
- Radiomics and Machine Learning in Medical Imaging
- Radiation Dose and Imaging
- Estrogen and related hormone effects
- Receptor Mechanisms and Signaling
- Advanced Nanomaterials in Catalysis
- Eicosanoids and Hypertension Pharmacology
- Traditional Chinese Medicine Analysis
- Pharmacogenetics and Drug Metabolism
- Medical Imaging Techniques and Applications
- Pulmonary Hypertension Research and Treatments
- Cell death mechanisms and regulation
- Innovative Microfluidic and Catalytic Techniques Innovation
- Cardiovascular Function and Risk Factors
- Sulfur Compounds in Biology
- Functional Brain Connectivity Studies
- Tryptophan and brain disorders
- Cancer-related gene regulation
Affiliated Hospital of Southwest Medical University
2020-2024
Anshun University
2022
Kaili University
2014-2021
Yinchuan First People's Hospital
2013-2014
Ningxia Medical University
2008-2014
Nanjing Medical University
2003-2006
High-entropy nanomaterials (HEMs) are a hot topic in the fields of energy and catalysis. However, terms promising biomedical applications, potential therapeutic studies involving HEMs unprecedented. Herein, we demonstrated high entropy two-dimensional layered double hydroxide (
Two-dimensional transition metal carbides and nitrides (MXenes) nanosheets with high photothermal conversion efficiency as well stability can efficiently generate remarkable hyperthermia for therapy (PTT) of cancer. However, mono-MXenes cannot exhibit precise diagnosis treatment to complete ablation cancer cells in the PTT process. To overcome this dilemma, an "all-in-one" nanoplatform titanium carbide (Ti
Abstract Objectives This study was designed to explore the effect and mechanism of matrine, an active component Chinese traditional medicine, on isoproterenol-induced acute cardiotoxicity in rats. Methods Acute myocardial injury induced rats by daily subcutaneous injection isoproterenol (85 mg/kg) for two days. Haemodynamic biochemical parameters were measured histopathological examination performed. Key findings Chronic oral administration matrine (50, 100 or 200 mg/kg per day 10 days)...
Abstract Objectives This study was designed to investigate the cardioprotective effects of matrine on regulation endothelial nitric oxide synthase (eNOS) and asymmetric dimethylarginine (ADMA) in isoproterenol-induced acute myocardial ischaemic rats. Methods Male Sprague–Dawley rats were pretreated with (200, 100 50 mg/kg) orally for 10 days. Acute injury induced by subcutaneous injection isoproterenol. Serum haemodynamic parameters, histopathological variables expression protein levels...
Background: Development of versatile nanoplatform still remains a great challenge due to multistep synthesis and complicated compositions. Therefore, it is significant develop facile method synthesize nanocomposite achieve multimodal imaging even imaging-guided cancer therapeutics. Methods Results: In our study, hyaluronic acid-functionalized iron (II) tungstate nanoparticles (HA-FeWO 4 NPs) were successfully synthesized as by one-pot hydrothermal procedure. The formed multifunctional...
Objectives It is necessary to develop a high-performance and biocompatible contrast agent accurately diagnose various diseases via in vivo computed tomography (CT) imaging. Here, we synthesized small molecular Bi-DOTA complex as for vitro CT bioimaging. Materials Methods In our study, was fabricated through facile one-pot synthesis strategy. The formed characterized different techniques. Furthermore, used bioimaging verify its X-ray attenuation ability, especially kidney imaging,...
Non-intrusive imaging of gastrointestinal (GI) tract using computed tomography (CT) contrast agents is the most significant issues in diagnosis and treatment GI diseases. Moreover, spectral CT, which can generate monochromatic images to display X-ray attenuation characteristics agents, provides a better sensitivity for diagnose inflammatory bowel disease (IBD) than convention CT imaging.Herein, convenient one-pot synthesis method provided fabrication small-molecule lanthanide complex...
The present study was designed to investigate the cardioprotective effects of betaine on acute myocardial ischemia induced experimentally in rats focusing regulation signal transducer and activator transcription 3 (STAT3) apoptotic pathways as potential mechanism underlying drug effect. Male Sprague Dawley were treated with (100, 200, 400 mg/kg) orally for 40 days. Acute ischemic injury by subcutaneous injection isoproterenol (85 mg/kg), two consecutive Serum cardiac marker enzyme,...
In this study, we aimed to utilize computed tomography (CT)-derived radiomics and various machine learning approaches differentiate between invasive mucinous adenocarcinoma (IMA) non-mucinous (INMA) preoperatively in solitary pulmonary nodules (SPN) ≤3 cm.