A5086835862- Gene Regulatory Network Analysis
- Bioinformatics and Genomic Networks
- Microbial Metabolic Engineering and Bioproduction
- Robotic Locomotion and Control
- Computational Drug Discovery Methods
- Modular Robots and Swarm Intelligence
- Robotic Path Planning Algorithms
- Robotics and Automated Systems
- Reinforcement Learning in Robotics
- Evolutionary Algorithms and Applications
- Natural Language Processing Techniques
- Multi-Agent Systems and Negotiation
- Gene expression and cancer classification
- Fungal and yeast genetics research
- Speech and Audio Processing
- Genetics, Bioinformatics, and Biomedical Research
- AI-based Problem Solving and Planning
- Embedded Systems Design Techniques
- Cell Image Analysis Techniques
- Topic Modeling
- Robot Manipulation and Learning
- Single-cell and spatial transcriptomics
- Prosthetics and Rehabilitation Robotics
- Speech and dialogue systems
- Influenza Virus Research Studies
Systems Biology Institute
2015-2024
Okinawa Institute of Science and Technology Graduate University
2015-2024
Sony Corporation (United States)
2001-2024
InteraXon (Canada)
2024
University of Toronto
2024
Seoul National University
2024
Sony Computer Science Laboratories
2011-2023
Sony (Japan)
2023
The Alan Turing Institute
2021-2023
RIKEN Center for Integrative Medical Sciences
2013-2022
This study describes comprehensive polling of transcription start and termination sites analysis previously unidentified full-length complementary DNAs derived from the mouse genome. We identify 5' 3' boundaries 181,047 transcripts with extensive variation in arising alternative promoter usage, splicing, polyadenylation. There are 16,247 new protein-coding transcripts, including 5154 encoding proteins. Genomic mapping transcriptome reveals transcriptional forests, overlapping on both...
PANTHER is a large collection of protein families that have been subdivided into functionally related subfamilies, using human expertise. These subfamilies model the divergence specific functions within families, allowing more accurate association with function (ontology terms and pathways), as well inference amino acids important for functional specificity. Hidden Markov models (HMMs) are built each family subfamily classifying additional sequences. The latest version, 5.0, contains 6683...
Article Free Access Share on RoboCup: The Robot World Cup Initiative Authors: Hiroaki Kitano Sony Computer Science Lab., 3-14-13 Higashi-Gotanda, Shinagawa, Tokyo 141 Japan JapanView Profile , Minoru Asada Dept. of Mechanical Engineering, Osaka University, Suita, 565 Yasuo Kuniyoshi Electrotechnical laboratory, 1-1-4 Umezono, Tsukuba, 305 Itsuki Noda Eiichi Osawa Authors Info & Claims AGENTS '97: Proceedings the first international conference Autonomous agentsFebruary 1997 Pages...
Understanding of the logic and dynamics gene-regulatory biochemical networks is a major challenge systems biology. To facilitate this research topic, we have developed modeling/simulating tool called CellDesigner. CellDesigner primarily has capabilities to visualize, model, simulate networks. Two characteristics embedded in boost its usability create/import/export models: 1) solidly defined comprehensive graphical representation (systems biology notation) network models 2) markup language...
Increased availability of bioinformatics resources is creating opportunities for the application network pharmacology to predict drug effects and toxicity resulting from multi-target interactions. Here we present a high-precision computational prediction approach that combines two elaborately built machine learning systems multiple molecular docking tools assess binding potentials test compound against proteins involved in complex network. One re-scoring function evaluate modes generated by...
The Robot World-Cup Soccer (RoboCup) is an attempt to foster AI and intelligent robotics research by providing a standard problem where wide range of technologies can be integrated examined. first RoboCup competition will held at the Fifteenth International Joint Conference on Artificial Intelligence in Nagoya, Japan. A robot team must actually perform soccer game, incorporating various technologies, including design principles autonomous agents, multiagent collaboration, strategy...
Lenvatinib is a multiple receptor tyrosine kinase inhibitor targeting mainly vascular endothelial growth factor (VEGF) and fibroblast (FGF) receptors. We investigated the immunomodulatory activities of lenvatinib in tumor microenvironment its mechanisms enhanced antitumor activity when combined with programmed cell death-1 (PD-1) blockade. Antitumor was examined immunodeficient immunocompetent mouse models. Single-cell analysis, flow cytometric immunohistochemistry were used to analyze...