A5067765950- Mitochondrial Function and Pathology
- Genetic Neurodegenerative Diseases
- Veterinary Equine Medical Research
- Biochemical effects in animals
- Veterinary Pharmacology and Anesthesia
- Reproductive Biology and Fertility
- Animal Diversity and Health Studies
- Corneal surgery and disorders
- Sperm and Testicular Function
- Animal Nutrition and Physiology
- Muscle Physiology and Disorders
- Animal Behavior and Welfare Studies
- Tendon Structure and Treatment
- Ocular Surface and Contact Lens
- Inflammatory Bowel Disease
- Gut microbiota and health
- Vector-borne infectious diseases
- Selenium in Biological Systems
- Rabbits: Nutrition, Reproduction, Health
- Probiotics and Fermented Foods
- ATP Synthase and ATPases Research
- Ureteral procedures and complications
- Environmental Toxicology and Ecotoxicology
- Reproductive System and Pregnancy
- Cancer, Hypoxia, and Metabolism
Mansoura University
2018-2025
Auburn University
2014-2015
Abstract Promising therapy is needed for treating inflammatory bowel diseases (IBD) to overcome current treatment that inefficient and associated with unnecessary health risks. Recently, the concept of incorporating natural products into nanocarriers has been intended as a promising IBD via modulating their stability bioavailability. Thus, we aimed explore potential alleviating effects dietary nano-supplement combined bacillus strains ( Bacillus amyloliquefaciens ; BANPs) in colitis model....
Previous studies have demonstrated the protective signaling of hypoxia-inducible factor (HIF)-1 α against ischemia-reperfusion (I/R) injury in heart. In present study, we provide further evidence for a cardioprotective mechanism by HIF-1α I/R exerted via mitochondrial protein frataxin, which regulates Fe-S cluster formation. Disruption frataxin has been found to induce iron overload and subsequent ROS production. We observed that expression was elevated mice hearts subjected injury, this...
Background: We investigated the anti-cancer effect of carnosine-loaded niosomes (Car-NIO) and melittin-loaded (Mel-NIO) with olaparib in breast cancer cell lines (MCF-7 MDA-MB-231). Methods: The thin film method was used for preparing characterized terms morphology, size, polydispersity index (PDI). further evaluated impact these peptides on cells viability, RT-qPCR assays, malondialdehyde (MDA) activity, cycle progression, to determine if are linked carnosine melittin's anti-proliferative...
This study investigated the potential neuroprotective role of Moringa oleifera leaf powder (MOLP) dietary supplementation on imidacloprid (IMD)-induced neurobehavioral disturbances, oxidative stress, and apoptosis in broiler chicken brains. In a 6 week trial, 150 day-old commercial meat-type Ross 308 chicks were randomly divided into five equal groups 30 each. The control MOLP fed basal diet containing 25 g MOLP/kg, respectively, for weeks. IMD group was 2 weeks, followed by 50 mg IMD/kg 4 +...
Doxorubicin (DOX) is a highly effective anti-neoplastic agent; however, its cumulative dosing schedules are clinically limited by the development of cardiotoxicity. Previous studies have attributed cause DOX-mediated cardiotoxicity to mitochondrial iron accumulation and ensuing reactive oxygen species (ROS) formation. The present study investigates role frataxin (FXN), iron-sulfur biogenesis protein, in dysfunction. Athymic mice treated with DOX (5 mg/kg, 1 dose/wk treatments, followed 2-wk...
Appropriate skeletal muscle development in poultry is positively related to increasing its meat production. Synthetic peptides with growth hormone-boosting properties can intensify the effects of endogenous hormones. However, their on mRNA and miRNA expression profiles that control post-hatching broiler chicks unclear. Thus, we evaluated possible synthetic peptide (GHBP) inclusion a chicken’s rate, development-related genes myomiRs, serum biochemical parameters, myofiber characteristics. A...
Buffaloes represent a major source of milk production, especially in developing countries including Egypt. The buffalo foot is frequently involved large proportion lameness cases. relatively small size and complexity its structures often render the radiographic evaluation challenging. Magnetic resonance imaging (MRI) noninvasive technique that regarded as both safe accurate for assessment disorders man animals. purpose current investigation was to describe MRI anatomy using cadaveric hind...
The molecular identification and antigenic characterization of P0 protein in Babesia divergens , a blood parasite veterinary zoonotic importance, were carried out this study for use developing subunit vaccines against B. infection. Recombinant encoding (BdP0) was developed Escherichia coli its antiserum generated mice further characterization. Anti-rBdP0 serum had specific interaction with the corresponding legitimate protein, as confirmed by Western blotting indirect fluorescent antibody...
Understanding the clinical anatomy of head is essential for performing proper inferior alveolar nerve (IAN) block anesthesia to facilitate invasive dental procedures in camels. However, osteometric data related IAN camels are lacking. This study was carried out accurately locate mandibular foramen (MF) and course camel establish an approach its localization practice. To achieve these aims, eight measurements were used determine location MF relation surrounding structures six cadaveric skulls...
It is likely that superficial corneal epithelial cells (SCECs) of the dromedary camels have a significant role in their survival at arid and semiarid regions. To best our knowledge, SCECs camels' eyes not been characterized previously using scanning electron microscopy (SEM), combined with morphometric analysis. Therefore, current study, we aim to describe shape, topographical distribution, density associated analysis SEM. Twelve healthy adult corneas were obtained immediately after...
Background: Diabetes is at epidemic proportions, with the major form of fatality due to congestive heart failure triggered by myocardial infarction (MI). The impaired insulin signalling in diabetic leads energy dysregulation that compromises cardioprotective mechanism against ischemic injury. Therefore understanding how mitochondrial energetics altered would greatly advance knowledge base for improving outcomes from patients. Methods/Findings: We observed db/db mice (leptin deficient, type 2...
Abstract Increased reactive oxygen species (ROS) generation may disrupt the oocytes function and their competence. In this study, we introduced BTZO‐1, a new supplement that can regulate oxidative stress. Addition of BTZO‐1 during IVM bovine improved developmental competence in term improvement blastocyst rates. addition, quality produced embryos was by decreasing apoptosis level showing decreased number TUNNEL positive cells.