- Vascular Anomalies and Treatments
- Sharing Economy and Platforms
- Gastric Cancer Management and Outcomes
- Eosinophilic Esophagitis
- COVID-19 and healthcare impacts
- Telemedicine and Telehealth Implementation
- Microscopic Colitis
- Inflammatory Bowel Disease
- Esophageal and GI Pathology
- Gastrointestinal Bleeding Diagnosis and Treatment
- Gastroesophageal reflux and treatments
- Colorectal Cancer Screening and Detection
- Healthcare Systems and Technology
- COVID-19 Clinical Research Studies
- Colorectal Cancer Treatments and Studies
- Helicobacter pylori-related gastroenterology studies
- Tracheal and airway disorders
- Infection Control and Ventilation
- Anorectal Disease Treatments and Outcomes
- Respiratory Support and Mechanisms
- Mobile Health and mHealth Applications
- Occupational and environmental lung diseases
- COVID-19 diagnosis using AI
- Infectious Aortic and Vascular Conditions
- Abdominal vascular conditions and treatments
Azienda Ospedaliera Ospedale Maggiore
2020-2025
Fondazione IRCCS Ca' Granda Ospedale Maggiore Policlinico
2019-2021
Azienda Socio Sanitaria Territoriale Grande Ospedale Metropolitano Niguarda
2021
University of Milan
2019-2020
Abstract Background and Aims A similar course of COVID-19 in patients with inflammatory bowel diseases [IBD] the general population has been reported. However, disease prevalence IBD is presently unknown. In this prospective observational study, we aimed at determining SARS-CoV2 infection treated biologic therapy. Methods From under therapy recruited from three different locations Italy Germany, 354 sera were evaluated for antibody presence by RBD ELISA. Control groups were: i] age-matched...
Telehealth refers to the opportunity provide healthcare remotely by telecommunication technologies, including personal computers, telephones and smartphones. The fundamental aim of telehealth is increase access care, despite physical distances, lack transportation or shortage medical staff. It allows patient assistance, clinical monitoring potentially some interventions [[1]Dorsey E.R. Topol E.J. State telehealth.N Engl J Med. 2016; 375: 154-161Crossref PubMed Scopus (743) Google Scholar]....
Abstract Background and study aim Pre-endoscopic use of a preparation with tensioactive mucolytic agents improved gastric mucosa visualization in Eastern studies. Data on Western population are scanty. Patients methods This prospective, endoscopist-blinded, randomized enrolled patients who underwent esophagogastroduodenoscopy single center. Before endoscopy patients, were to receive or not an oral simethicone N-acetylcysteine water. A pretested score (Crema Stomach Cleaning Score [CSCS]) for...
Objective SARS-CoV-2 outbreak is spreading worldwide. As a consequence of the new circumstances, almost all endoscopic units underwent in-depth reorganization involving patients’ selection. We analyzed efficacy newly adopted triage. Methods In March 2020, we monitored endoscopies to evaluate effects novel selective triage aimed reduce number investigations and viral spread/contagions. Clinical-demographic data patients, indications, type endoscopy, findings (subtyped in major minor), finding...
Intestinal metaplasia (IM) is the point of no return in gastric carcinogenesis, and patients with extensive (antrum plus corpus) IM are at high risk developing cancer. We evaluated impact improved gastroscopy quality on detection an Italian area for cancer.Data consecutive biopsies according to updated Sydney System observed 2013, 2016 2019 resulting diagnosis were retrieved. In first period, endoscopy was performed standard white light instruments. second preendoscopic preparation...
Background and study aims This longitudinal prospective evaluated the long-term outcome of endoscopic treatment gastrointestinal bleeding in hereditary hemorrhagic telangiectases (HHT), its safety predictors. Patients methods Consecutive patients with HHT either anemia disproportionate to epistaxis or overt received argon plasma coagulation (APC). Hemoglobin levels transfusion requirements were before after treatment. Treatment effectiveness was classified as: 1) complete: hemoglobin level...
4068 Background: Treatment options for advanced or metastatic gastric cancer (A/MGC) are limited and therefore inclusion of novel substances is necessary. Few studies have confirmed the activity tolerability combination oxaliplatin (OXA) 5-fluorouracil (5-FU) modulated with leucovorin (LV) administered to patients (pts) A/MGC. Methods: Thirty-five A/MGC treated FOLFOX-4 regimen. All had a pathologically at least one measurable lesion, 14 pts (40%) were previously untreated 21 (60%) received...
Abstract Background Hereditary hemorrhagic telangiectasia (HHT) is a multisystemic inherited vascular disease characterized by heterogeneous clinical presentation and prognosis. Dietary evaluation relevant in HHT patients to provide adequate iron nutrient intake. Additionally, different dietary items have been reported precipitate epistaxis this setting. Our primary aim was investigate the habits of through food-frequency questionnaire (FFQ) evaluate presence precipitants and/or protective...
Metastatic/advanced colorectal cancer is considered a resistant disease and oncologic emergencies secondary to advanced may be regarded with nihilistic attitude. The objective of this report emphasize the efficacy oxaliplatin/5-fluorouracil/leucovorin regimen (FOLFOX-4) in three patients presenting colon cancer. first case was 40-year-old man severe respiratory insufficiency due massive carcinomatous lymphangitis; subsequently cecal adenocarcinoma diagnosed. patient's conditions became...
Abstract Background Tofacitinib is an oral janus kinase inhibitor (JAK) approved for patients with moderate to severe ulcerative colitis (UC) and either inadequate response or loss of intolerance conventional biologic therapy. The 5-year 10-year cumulative risk colectomy in UC 10%–15%.1 Due the increasing number anti tumor necrosis factor (TNF)-alfa non responders, tofacitinib seems a valuable therapeutic alternative. This study aims assess effectiveness preventing moderate-to-severe...
Results A 71 years-old woman referred to our Endoscopy Unit for recurrent post-prandial epigastric pain.She was a smoker (40 packs/year) with history of systemic hypertension and breast cancer. Since 2019, the patient had undergone several esophagogastroduodenoscopies (EGDs), which showed patchy erosions gastric antrum. The histological report evidenced mild gastritis (OLGA score I). previous abdominal CT scan (without contrast medium) no pathological features. During last three weeks, she...
Eosinophilic gastroenteritis (EG) is a rare condition characterized by patchy eosinophilic inflammation of one or more layers the gastrointestinal tract with no secondary causes eosinophilia. EG treatable disease and, generally, patients show positive response to steroid therapy. Sometimes can present as acute abdomen, and appendicular involvement has seldom been described in course EG. In our case report we aimed emphasize how useful ultrasound valuable tool for diagnosing monitoring...
Aims During esophagogastroduodenoscopy (EGDS) bubbles, bile and mucus often compromise the endoscopic visualization. Consensus about importance of tensioactive mucolytic drugs such as symetichone (SIM) N-acetylcysteine (NAC) is lacking in Western world.
Abstract Background: Hereditary hemorrhagic telangiectasia (HHT) is a multisystemic inherited vascular disease characterized by heterogeneous clinical presentation and prognosis. Dietary evaluation relevant in HHT patients to provide adequate iron nutrient intake. Additionally, different dietary items have been reported precipitate epistaxis this setting. Our primary aim was investigate the habits of through food-frequency questionnaire (FFQ) evaluate presence precipitants and/or protective...