- Global Maternal and Child Health
- Malaria Research and Control
- Vaccine Coverage and Hesitancy
- Mosquito-borne diseases and control
- Child Nutrition and Water Access
- Climate Change and Health Impacts
- Global Cancer Incidence and Screening
- Global Health Care Issues
- Global Public Health Policies and Epidemiology
- Health disparities and outcomes
- SARS-CoV-2 and COVID-19 Research
- Viral Infections and Outbreaks Research
- HIV/AIDS Impact and Responses
- HIV/AIDS Research and Interventions
- COVID-19 epidemiological studies
- Influenza Virus Research Studies
- COVID-19 and healthcare impacts
- Cervical Cancer and HPV Research
- Colorectal Cancer Screening and Detection
- Virology and Viral Diseases
- Health Systems, Economic Evaluations, Quality of Life
- COVID-19 Clinical Research Studies
- Adolescent and Pediatric Healthcare
- Injury Epidemiology and Prevention
- Advances in Oncology and Radiotherapy
Malaria Consortium
2023-2025
University of Cape Town
2018-2024
South African Medical Research Council
2018-2024
Institute for Health Metrics and Evaluation
2019-2024
University of Washington
2020-2024
Women's Health Research Institute
2022
Western Cape Department of Health
2021-2022
University College London
2021
Background Over the last 30 years, South Africa has experienced four ‘colliding epidemics’ of HIV and tuberculosis, chronic illness mental health, injury violence, maternal, neonatal, child mortality, which have had substantial effects on health well-being. Using data from 2019 Global Burden Diseases, Injuries Risk Factors Study (GBD 2019), we evaluated national provincial trends progress towards important Sustainable Development Goal targets 1990 to 2019. Methods We analysed GBD estimates...
Differences between urban and rural contexts in terms of sociodemographic characteristics, geographical features risk perceptions may lead to disparities coverage related outcomes community-based preventive interventions, such as seasonal malaria chemoprevention (SMC). This study investigated urban-rural differences SMC other programme outcomes, well child caregiver characteristics target populations nine implementing states Nigeria during the 2022 round.
Abstract Background Seasonal malaria chemoprevention (SMC) is an effective intervention to prevent in children locations where the burden of high and transmission seasonal. There growing evidence suggesting that SMC with sulfadoxine–pyrimethamine amodiaquine can retain its level effectiveness East Southern Africa despite resistance concerns. This study aims generate on when delivered under programmatic conditions area unknown anti-malarial drug profile Northern Bahr el-Ghazal region South...
Abstract Background Seasonal malaria chemoprevention (SMC) is a highly effective intervention for prevention in high burden areas with seasonal transmission, historically implemented the Sahel. Mozambique contributes to 4% of global cases. Malaria Consortium, partnership National Control Programme, conducted two-year phased SMC study Nampula province using sulfadoxine-pyrimethamine (SP) plus amodiaquine (AQ), or SPAQ, children under five. Phase one results presented here highlight...
Vaccine hesitancy, a growing global problem which is aggravated by vaccine related rumors and (mis)information, has the potential to reverse gains from vaccination. Areas covered: We describe selection of vaccine-related events that have made headlines highlight effects these had on acceptance. Drawing cases, an adaptation epidemiological modeling spread ideas, we propose hesitancy can be grouped into two categories: 'baseline' 'reactive' hesitancy. 'Baseline' refers level refusal or delay...
Socioeconomic and health inequalities remain a huge problem in post-apartheid South Africa. Despite substantial efforts at ensuring universal access to vaccines, many children under-vaccinated the country. This study aimed assess prevalence factors associated with incomplete vaccination first year of life, among aged 12-23 months The is secondary analysis 2016 African Demographic Health Survey. A multivariable logistic regression model was applied data on 708 months. outcome, completeness,...
Missed opportunities for vaccination (MOV) may be among the factors responsible suboptimal coverage in South Africa. However, magnitude and determinants of MOV country are not known. Thus, this study seeks to assess prevalence country. Africa is sub-divided into nine administrative provinces. We used nationally representative data from 2016 African Demographic Health Survey. considered have occurred if a child aged 12-23 months old had taken all scheduled basic vaccine doses despite having...
Despite South Africa’s substantial investments in and efforts at ensuring universal access to immunisation services, progress has stalled remains suboptimal across provinces districts. An additional challenge is posed by the ongoing coronavirus disease 2019 (COVID-19) pandemic, which disrupted services globally, including Africa. While there growing evidence that missed opportunities for vaccination (MOV) are a major contributor not much known about burden determinants of MOV African...
Despite the substantial efforts at ensuring universal access to routine immunisation services among children in South Africa, major gaps coverage remain. This study assessed magnitude of missed opportunities for vaccination (MOV) and associated factors aged 0-23 months attending primary health care (PHC) facilities Cape Town. We used multilevel binomial logistic regression models explore individual contextual with MOV, Level 1, nested within PHC (Level 2). A total 674 their caregivers were...
Abstract Background As part of implementation quality standards, community distributors are expected to ensure that only age-eligible children (aged 3–59 months) receive seasonal malaria chemoprevention (SMC) medicines during monthly campaigns. There is uncertainty about the extent which SMC administered ineligible children. This study aimed assess magnitude this occurrence, while exploring factors associated with it across nine states where was delivered in Nigeria 2022 round. Methods...
Malaria Consortium supports delivery of seasonal malaria chemoprevention (SMC) to children ages 3-59 months using sulfadoxine-pyrimethamine plus amodiaquine. Lot quality assurance sampling (LQAS) was adapted as a cost-efficient method for end-of-cycle SMC monitoring surveys across supported countries and an implementation challenges reporting system established in Nigeria. We present case study its application Nasarawa State. LQAS facilitated timely local performance assessment 16...