A5109781798- MicroRNA in disease regulation
- Cancer-related molecular mechanisms research
- Circular RNAs in diseases
- Cancer, Hypoxia, and Metabolism
- RNA modifications and cancer
- Advanced biosensing and bioanalysis techniques
- Phytochemistry and Biological Activities
- Tissue Engineering and Regenerative Medicine
- Plant Molecular Biology Research
- Virus-based gene therapy research
- Neonatal Respiratory Health Research
- Nanoplatforms for cancer theranostics
- Immunotherapy and Immune Responses
- Nerve injury and regeneration
- Flavonoids in Medical Research
- Plant Gene Expression Analysis
- RNA Research and Splicing
- Electrospun Nanofibers in Biomedical Applications
- Cancer Research and Treatments
- RNA Interference and Gene Delivery
- Traditional Chinese Medicine Analysis
- Photosynthetic Processes and Mechanisms
Zhengzhou University
2024-2025
Peking University People's Hospital
2024
Peking University
2024
Southwest University
2024
Zhujiang Hospital
2024
Southern Medical University
2024
Sichuan Animal Science Academy
2021
Jingzhou Central Hospital
2020
Hebei Medical University
2015
Fourth Hospital of Hebei Medical University
2015
Previous research has demonstrated the feasibility of repairing nerve defects through acellular allogeneic grafting with bone marrow mesenchymal stem cells. However, adult tissue–derived cells encounter various obstacles, including limited tissue sources, invasive acquisition methods, cellular heterogeneity, purification challenges, senescence, and diminished pluripotency proliferation over successive passages. In this study, we used induced pluripotent cell-derived cells, known for their...
Abstract The efficacy of in situ cancer vaccines (ISCVs) is hindered by the poor immunogenicity tumor cells. Here, PRIZE, a P53‐repair nanosystem based on virus‐mimicking nanostructure to deliver p53 mRNA and Zn (II) into cells, domesticating cells restoring intracellular P53 levels bolster their immunogenicity, designed. PRIZE ensures precise delivery sites, stabilizes with its biomineralized structure, extends half‐life P53. This research highlights that can efficiently repair...
Abstract Acute lung injury (ALI) is a severe disease with high mortality and poor prognosis, characterized by excessive uncontrolled inflammatory response. Vascular endothelial growth factor A (VEGF‐A) contributes to the development progression of ALI. The aim this study was evaluate role glucose transporter 1 (GLUT1) in alveolar epithelial VEGF‐A production lipopolysaccharide (LPS)‐induced An ALI mouse model induced LPS oropharyngeal instillation. Mice were challenged then treated WZB117,...
MicroRNA (miR)‑130a has been reported to promote cancer growth; however, its role during acute myeloid leukemia (AML) is not completely understood. In the present study, effects of miR‑130a on sensitivity AML cells Adriamycin (Adr) were investigated. 5‑Aza‑2'‑deoxycytidine (5‑Aza‑dC) was used stimulate Adr resistance in cells, and cell viability expression determined using Cell Counting Kit‑8 (CCK‑8) assay reverse transcription‑quantitative PCR, respectively. overexpression knockdown...
To compare the chemical differences in 4 commercial specifications of Scutellaria Radix, research affection decayed central xylem part on crude drug's composition and provide scientific data for production, processing, sale clinical applications Scutellariae Radix.Macroscopical identification method was used observation different including Qinwang, Tiaoqin both 1st class 2nd inferior samples. HPLC fingerprint to analyze chemically non-decayed as well complete sample, results were described...
Gene expression profiles of blood can reflect the physiopathologic status immune system. The dynamic microRNA (miRNA) peripheral from pigs at different developmental stages, and how differential miRNAs might relate to system development, are unknown. In this study, samples taken five stages were used construct 15 miRNA libraries (three biological replicates/stage): 0 days (newborn), 30 (weaning), 60 (weaned), 180 360 (puberty). We identified 295 known mature miRNAs. Hierarchical clustering...